Chicago, IL to Tupelo, MS bus

Wed, Aug 05
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Chicago, IL to Tupelo, MS Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
09:45AM
Arrival Time
11:05PM
Duration
13h20
Departure days
Mon, Fri
Cheapest price
80
Operator
Greyhound
Departure Time
10:40PM
Arrival Time
10:40AM
Duration
12h00
Departure days
Mon, Fri
Cheapest price
79

FAQs: Bus from Chicago, IL to Tupelo, MS

Find answers to the most common questions about traveling from Chicago, IL to Tupelo, MS by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tupelo, MS, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Chicago, IL to Tupelo, MS leaves at 5:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to Tupelo, MS leaves at 11:15 PM.
When departing from Chicago, IL , you have various bus station options to start your journey from including Chicago, Greyhound Bus Station, Chicago, Union Station (Amtrak), IL . When arriving in Tupelo, MS , you can end your journey in bus stations like Tupelo, S Eason Blvd (Brothers Quick Stop), MS .Passengers board the bus most frequently from Chicago, Greyhound Bus Station, which is located around 1 miles (2 km) away from the city centre, and they get off the bus at Tupelo, S Eason Blvd (Brothers Quick Stop), MS, located 2 away from the city centre.
Yes, you can take a between Chicago, IL and Tupelo, MS.
No, the bus from Chicago, IL to Tupelo, MS has no accessibility options.
No, there are no bathrooms on board the bus from Chicago, IL to Tupelo, MS.
No, bikes are not allowed on board the bus from Chicago, IL to Tupelo, MS.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Chicago, IL to Tupelo, MS.
No, luggage for the bus from Chicago, IL to Tupelo, MS needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to Tupelo, MS.
Unfortunately, pets are not allowed on the bus from Chicago, IL to Tupelo, MS.
No, there are no USB plugs on board the bus from Chicago, IL to Tupelo, MS.
No, there is no WiFi on board the bus from Chicago, IL to Tupelo, MS.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tupelo, MS, travelers should be cautious of common safety concerns such as petty theft and vehicle break-ins, especially in crowded or tourist-heavy areas. It is advisable to keep valuables secure and be aware of surroundings. Scams are relatively uncommon but travelers should remain vigilant against overcharging or misleading offers from unofficial vendors. Staying in well-populated areas and using trusted transportation options helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Chicago, IL to Tupelo, MS

Most Chicago, IL to Tupelo, MS buses use the Chicago, Greyhound Bus Station to Tupelo, S Eason Blvd (Brothers Quick Stop) station pair. Use this guide to compare Chicago, IL and Tupelo, MS bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Chicago
Arrival bus stations in Tupelo

Which Chicago, IL station do buses to Tupelo, MS leave from?

Buses from Chicago, IL to Tupelo, MS leave from Chicago, Greyhound Bus Station. The station is 1 miles (3 km) from Chicago, IL city centre at 630 W Harrison St, Chicago, IL 60607, USA.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Chicago, Greyhound Bus Station from Chicago city centre

Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:

Bus7 · 8m · €3 · every ~6 min

Chicago, Greyhound Bus Station bus station facilities and services

Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Snack shop and vending machines available

Wi-Fi and ATMs

Free Wi-Fi in waiting area. ATMs are located near entrance.

Tickets and information

Ticket office support is available at Chicago, Greyhound Bus Station.

Parking, taxis and toilets

Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.

Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Chicago, Union Station (Amtrak) from Chicago city centre

Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:

Bus28, 151 · 7m · €3 · every ~13 min

Chicago, Union Station (Amtrak) bus station facilities and services

Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Multiple dining options are available inside the station.

Wi-Fi and ATMs

Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.

Tickets and information

Ticket office support is available at Chicago, Union Station (Amtrak).

Parking, taxis and toilets

Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.

More options for your journey from Chicago, IL to Tupelo, MS

Here are some other resources that might have the information you need

HomeBusesBuses in USAChicago, IL to Tupelo, MS bus

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