The cheapest and fastest buses from Kansas City, MO to Tupelo, MS
Cheapest price
$118
Average price
$118
Fastest journey
14 h 25 m
Average duration
16 h 38 m
Buses per day
2
Distance
751 km
The best way to find a cheap bus ticket from Kansas City, MO to Tupelo, MS is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Kansas City, MO to Tupelo, MS will cost around $118 if you buy it on the day, but the cheapest tickets can be found for only $118.
It's difficult to get from Kansas City, MO to Tupelo, MS without transferring at least 2 times.
FlixBus+
· 8:40 AM14h25Kansas City, Jefferson Lines11:05 PMTupelo, S Eason Blvd (Brothers Quick Stop), MS$1181One-way2 transfers
· · 3:50 PM18h50Kansas City, Jefferson Lines10:40 AMTupelo, S Eason Blvd (Brothers Quick Stop), MS$1181One-way2 transfers
FlixBus+
· 8:40 AM14h25Kansas City, Jefferson Lines11:05 PMTupelo, S Eason Blvd (Brothers Quick Stop), MS$1181One-way2 transfers
· · 3:50 PM18h50Kansas City, Jefferson Lines10:40 AMTupelo, S Eason Blvd (Brothers Quick Stop), MS$1181One-way2 transfers
Kansas City, MO to Tupelo, MS Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:40AM | Arrival Time 11:05PM | Duration 14h25 | Departure days Thu | Cheapest price $118 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 10:40AM | Duration 18h50 | Departure days Thu | Cheapest price $118 |
Live departures
Kansas City, MO to Tupelo, MS bus times
The table below shows live departures for Kansas City, MO to Tupelo, MS buses for tomorrow, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus+![]() | 8:40 AM Kansas City, Jefferson Lines | 14h25 | 11:05 PM Tupelo, S Eason Blvd (Brothers Quick Stop), MS | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Kansas City, MO to Tupelo, MS buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Kansas City, MO to Tupelo, MS
Take a bus from Kansas City, MO to Tupelo, MS and enjoy the approximately 466 miles (751 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Distance 466 miles (751 km) |
Average bus duration 11h 10m |
Buses per day 2 |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Sun |
Bus providers: Greyhound from Kansas City, MO to Tupelo, MSYou can travel by bus between Kansas City, MO to Tupelo, MS with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Kansas City, MO to Tupelo, MS
Find answers to the most common questions about traveling from Kansas City, MO to Tupelo, MS by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tupelo, MS, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Kansas City, MO to Tupelo, MS
Most Kansas City, MO to Tupelo, MS buses use the Kansas City, Jefferson Lines to Tupelo, S Eason Blvd (Brothers Quick Stop) station pair. Use this guide to compare Kansas City, MO and Tupelo, MS bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Kansas City, Jefferson Lines from Kansas City city centre
Most popular bus connections from Kansas City, MO
More options for your journey from Kansas City, MO to Tupelo, MS
Here are some other resources that might have the information you need
