- Recommended
Oren Dunn City Museum
Main local history museum with exhibits on Tupelo, the region, music heritage, and changing community life.
Buses from Kansas City, MO to Tupelo, MS run on average 2 times per day, taking around 11h 44m. Cheap bus tickets for this journey start at $128 if you book in advance.
The earliest bus runs at 13:40, the last at 20:50. The fastest bus covers the 466 miles (751 km) distance in 10h 45m.
Distance 466 miles (751 km) |
Average bus duration 11h 44m |
Cheapest ticket price $128 |
Buses per day 2 |
Fastest bus 10h 45m |
First bus 1:40 PM |
Last bus 8:50 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sun |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:40AM | Arrival Time 11:05PM | Duration 14h25 | Departure days Sun | Cheapest price $85 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 10:40AM | Duration 18h50 | Departure days Sun | Cheapest price $85 |
Discover the best of Tupelo, MS — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tupelo, MS trip today.
Main local history museum with exhibits on Tupelo, the region, music heritage, and changing community life.
Hands-on museum for children with interactive exhibits that make it a practical family stop in Tupelo.
Compact memorial museum at Elvis Presley Birthplace with artifacts and displays about his youth and family in Tupelo.
Major city park with trails, ponds, playgrounds, and event space; ideal for walking and relaxed outdoor time.
Downtown main street area with historic storefronts, local shops, murals, and a pleasant walkable atmosphere.
Lakeside park with walking paths, open lawns, and a calm setting for short strolls near central Tupelo.
Slow-smoked pork shoulder or ribs with a tangy, tomato-based sauce. Barbecue is central to North Mississippi gatherings and roadside dining.
Crisp catfish fillets, usually cornmeal-coated and fried. A staple across Mississippi, often served at family meals with hushpuppies and slaw.
Small fried cornmeal dumplings served with fish and barbecue. They are a classic Southern side found at many casual Mississippi restaurants.
Long-running bakery and cafe known for sandwiches, sweets, and a relaxed local vibe. Good for lunch, coffee, or dessert.
Popular local barbecue spot serving smoked meats, ribs, and Southern sides in a casual, family-friendly setting.
Refined Southern restaurant with steaks, seafood, and regional dishes in an intimate downtown atmosphere.
Moderate for U.S. travelers. Hotels and meals are usually cheaper than major cities, but car travel is common and adds fuel or rental costs.
Tip 15-20% at restaurants. Round up or tip 10-15% for taxis. Cafes often have tip jars or checkout prompts; small tips are optional.
Find answers to the most common questions about traveling from Kansas City, MO to Tupelo, MS by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tupelo, MS, this guide helps you travel smarter and with confidence.

Most Kansas City, MO to Tupelo, MS buses use the Kansas City, Jefferson Lines to Tupelo, S Eason Blvd (Brothers Quick Stop) station pair. Use this guide to compare Kansas City, MO and Tupelo, MS bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Kansas City, Jefferson Lines has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Kansas City, Jefferson Lines.
Ticket office support is available at Kansas City, Jefferson Lines.
Available at Kansas City, Jefferson Lines: Parking, Taxis, WC.
Accessibility facilities are available at Kansas City, Jefferson Lines: Wheelchair accessible.
Tupelo, S Eason Blvd (Brothers Quick Stop) is 2 km from Tupelo city centre. Public transport options include:
Tupelo, S Eason Blvd (Brothers Quick Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tupelo, S Eason Blvd (Brothers Quick Stop). ATMs are available at Tupelo, S Eason Blvd (Brothers Quick Stop).
Ticket office support is available at Tupelo, S Eason Blvd (Brothers Quick Stop).
Available at Tupelo, S Eason Blvd (Brothers Quick Stop): Parking, Taxis, WC.
Accessibility facilities are available at Tupelo, S Eason Blvd (Brothers Quick Stop): No dedicated facilities for disabled access.
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