Why should you book Kansas City, MO to Tupelo, MS buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Kansas City, MO to Tupelo, MS
Buses from Kansas City, MO to Tupelo, MS run on average 2 times per day, taking around 11h 44m. Cheap bus tickets for this journey start at $98 if you book in advance.
The earliest bus runs at 13:40, the last at 20:50. The fastest bus covers the 466 miles (751 km) distance in 10h 45m.
Distance 466 miles (751 km) |
Average bus duration 11h 44m |
Cheapest ticket price $98 |
Buses per day 2 |
Fastest bus 10h 45m |
First bus 1:40 PM |
Last bus 8:50 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sun |
Bus providers: Greyhound, FlixBus from Kansas City, MO to Tupelo, MSYou can travel by bus between Kansas City, MO to Tupelo, MS with Greyhound, FlixBus for as low as $98. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Kansas City, MO to Tupelo, MS
Find answers to the most common questions about traveling from Kansas City, MO to Tupelo, MS by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tupelo, MS, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Kansas City, MO to Tupelo, MS
Most Kansas City, MO to Tupelo, MS buses use the Kansas City, Jefferson Lines to Tupelo, S Eason Blvd (Brothers Quick Stop) station pair. Use this guide to compare Kansas City, MO and Tupelo, MS bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Kansas City, MO station do buses to Tupelo, MS leave from?
Getting to Kansas City, Jefferson Lines from Kansas City city centre
Kansas City, Jefferson Lines bus station facilities and services
Kansas City, Jefferson Lines has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Kansas City, Jefferson Lines.
Tickets and information
Ticket office support is available at Kansas City, Jefferson Lines.
Parking, taxis and toilets
Available at Kansas City, Jefferson Lines: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Kansas City, Jefferson Lines: Wheelchair accessible.
Which Tupelo, MS station do buses from Kansas City, MO arrive at?
Getting to Tupelo, S Eason Blvd (Brothers Quick Stop) from Tupelo city centre
Tupelo, S Eason Blvd (Brothers Quick Stop) is 2 km from Tupelo city centre. Public transport options include:
Tupelo, S Eason Blvd (Brothers Quick Stop) bus station facilities and services
Tupelo, S Eason Blvd (Brothers Quick Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tupelo, S Eason Blvd (Brothers Quick Stop). ATMs are available at Tupelo, S Eason Blvd (Brothers Quick Stop).
Tickets and information
Ticket office support is available at Tupelo, S Eason Blvd (Brothers Quick Stop).
Parking, taxis and toilets
Available at Tupelo, S Eason Blvd (Brothers Quick Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tupelo, S Eason Blvd (Brothers Quick Stop): No dedicated facilities for disabled access.
Most popular bus connections from Kansas City, MO
More options for your journey from Kansas City, MO to Tupelo, MS
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