Journey information
Overview: Bus from Calexico, CA to San Francisco, CA
Buses from Calexico, CA to San Francisco, CA run on average 4 times per day, taking around 12h 5m. Cheap bus tickets for this journey start at $64 (€51) if you book in advance.
The earliest bus runs at 16:20, the last at 16:20. The fastest bus covers the 525 miles (846 km) distance in 21h 20m.
Distance 525 miles (846 km) |
Average bus duration 12h 5m |
Cheapest ticket price $64 (€51) |
Buses per day 4 |
Fastest bus 21h 20m |
First bus 16:20 |
Last bus 16:20 |
Bus providers: FlixBus from Calexico, CA to San Francisco, CAYou can travel by bus between Calexico, CA to San Francisco, CA with FlixBus for as low as $64 (€51). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Calexico, CA to San Francisco, CA
Find answers to the most common questions about traveling from Calexico, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Calexico, CA to San Francisco, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Calexico, CA to San Francisco, CA
Most popular bus connections from Calexico, CA
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