The cheapest and fastest buses from Bethesda, MD to Chicago, IL
Cheapest price
$188
Average price
$188
Fastest journey
17 h 33 m
Average duration
18 h 39 m
Buses per day
3
Distance
948 km
The best way to find a cheap bus ticket from Bethesda, MD to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Bethesda, MD to Chicago, IL will cost around $188 if you buy it on the day, but the cheapest tickets can be found for only $188.
It's difficult to get from Bethesda, MD to Chicago, IL without transferring at least once.






Travel Information
Compare bus, train, and flight for Bethesda, MD to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Bethesda, MD to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $111. For those with little time consider booking a flight which can get you there in 2h 31m. The ticket price range depends on the travel mode: a bus costs an average of $111, and a flight costs an average of $399.
Distance: 589 miles (948 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$111 Average price Cheapest | $399 Average price | $158 Average price |
25h 0m Average total duration 24h 30m Onboard + 30m Additional time* | 5h 31m Average total duration Fastest 2h 31m Onboard + 3h 0m Additional time* | 17h 54m Average total duration 17h 24m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Bethesda, MD to Chicago, IL bus times
The table below shows live departures for Bethesda, MD to Chicago, IL buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:32 PM Bethesda, MD | 17h28 | 10:00 AM Chicago, IL | 1 transfer | |
![]() | 4:37 PM Bethesda, MD | 17h23 | 10:00 AM Chicago, IL | 2 transfers | |
| Monday, March 23 | |||||
![]() | 12:46 AM Bethesda, MD | 19h19 | 8:05 PM Chicago, IL | 1 transfer | |
![]() | 1:01 AM Bethesda, MD | 19h04 | 8:05 PM Chicago, IL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Bethesda, MD to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
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Mar 29
Why should you book Bethesda, MD to Chicago, IL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Washington Metropolitan Area Transit Authority to find the best option for your trip from Bethesda, MD to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Bethesda, MD to Chicago, IL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Bethesda, MD to Chicago, IL.
Journey information
Overview: Bus from Bethesda, MD to Chicago, IL
Buses from Bethesda, MD to Chicago, IL run on average 4 times per day, taking around 24h 30m. Cheap bus tickets for this journey start at $111 (€90) if you book in advance.
The earliest bus runs at 10:00, the last at 21:30. The fastest bus covers the 589 miles (948 km) distance in 17h 25m.
Distance 589 miles (948 km) |
Average bus duration 24h 30m |
Cheapest ticket price $111 (€90) |
Buses per day 4 |
Fastest bus 17h 25m |
First bus 10:00 |
Last bus 21:30 |
Bus providers: Greyhound, Washington Metropolitan Area Transit Authority from Bethesda, MD to Chicago, ILYou can travel by bus between Bethesda, MD to Chicago, IL with Greyhound, Washington Metropolitan Area Transit Authority for as low as $111 (€90). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Washington Metropolitan Area Transit Authority
FAQs: Bus from Bethesda, MD to Chicago, IL
Find answers to the most common questions about traveling from Bethesda, MD to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Bethesda, MD to Chicago, IL
Most popular bus connections from Bethesda, MD
More options for your journey from Bethesda, MD to Chicago, IL
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