Travel Information
Compare bus, train, and flight for Prague to Wuppertal
Omio recommends booking the train as it is the most popular option from Prague to Wuppertal among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €78 For those with little time, consider booking a flight, which has an average total journey time of 5h 1m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €78, while a flight costs an average of €391.
Distance: 328 miles (528 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
€164 Average price | €391 Average price | €78 Average price Cheapest | €113 Average price (fuel + tolls) |
9h 10m Average total duration 8h 40m Onboard + 30m Additional time* | 5h 1m Average total duration Fastest 3h 1m Onboard + 2h 0m Additional time* | 14h 1m Average total duration 13h 31m Onboard + 30m Additional time* | 6h 32m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Wuppertal:
A bus is €86 less than a train for this route with tickets for a train from Prague to Wuppertal costing on average €164.
A bus is €313 less than a flight for this route with tickets for a flight from Prague to Wuppertal costing on average €391.
Other travel options to Wuppertal take longer:
Train takes on average 9h 10m.
Bus takes on average 14h 1m.
Tickets start at around €164 compared to roughly €113 in fuel and tolls — a saving of about €-51.57. The journey takes 8h 40m versus 6h 32m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Prague to Wuppertal
How to get from Prague to Wuppertal by train, bus or flight.
Our recommendation
The best way to travel from Prague to Wuppertal is by taking a bus because it’s the best combination of price and speed.
3:10 PM14h40Prague5:50 AMWuppertal€541One-way0 transfers
Cheapest
3:10 PM14h40Prague5:50 AMWuppertal€541One-way0 transfers
Fastest
3:10 PM14h40Prague5:50 AMWuppertal€541One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Prague to Wuppertal
Travel to Wuppertal easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Wuppertal.

This is compared to other travel options from Prague to Wuppertal:
A bus is €86 less than a train for this route with tickets for a train from Prague to Wuppertal costing on average €164.
A bus is €313 less than a flight for this route with tickets for a flight from Prague to Wuppertal costing on average €391.
Other travel options to Wuppertal take longer:
Train takes on average 9h 10m.
Bus takes on average 14h 1m.
- Around 58 flights per day.
- Around 16 buses per day.
- Around 9 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Wuppertal as scheduled services by bus, train, and flight can vary by season or day of the week.
- Buses mostly depart from Prague, Central Train Station and arrive in Wuppertal, Oberbarmen Bahnhof.
- Trains mostly depart from Prague hlavní nádraží and arrive in Wuppertal Hbf.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Dusseldorf Airport.
- Travel with FlixBus to go to Wuppertal by bus.
- Travel with Lufthansa Cityline, KLM Cityhopper, Swiss, Eurowings, Lufthansa City Airlines, Air France, KLM, Qatar Airways, Air Dolomiti, Austrian Airlines, Lufthansa, Smartwings, Air Baltic, Turkish Airlines, Helvetic Airways, Lot Polish Airlines, Egypt Air, TAP Portugal, British Airways, Edelweiss Air to go to Wuppertal by flight.
- Travel with České dráhy, Deutsche Bahn to go to Wuppertal by train.
- 2 direct flights per day with Eurowings, Smartwings.
Travelling from Prague to Wuppertal: related information
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