- Must visit
Galleria degli Uffizi
World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. One of Florence’s essential art museums and often requires advance booking.
Cheapest price
$32
Average price
$32
Fastest journey
4 h 49 m
Average duration
4 h 49 m
Trains per day
1
Distance
241 km
The best way to find a cheap train ticket from San Donato Milanese to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Donato Milanese to Florence Santa Maria Novella will cost around $32 if you buy it on the day, but the cheapest tickets can be found for only $32.
Of the 1 trains that leave San Donato Milanese for Florence Santa Maria Novella on Mon, May 25, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct trains cover the 241 km distance in an average of 4 h 49 m but if you time it right, some trains will get you there in just 4 h 49 m .
On Mon, May 25 the slowest trains will take 4 h 49 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from San Donato Milanese to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $12. For those with little time consider booking a train which can get you there in 3h 33m. The ticket price range depends on the travel mode: a bus costs an average of $12, and a train costs an average of $23.
Distance: 149 miles (241 km)
| Train | Most popular Bus | Driving |
|---|---|---|
$32 Average price | $18 Average price Cheapest | $58 Average price (fuel + tolls) |
4h 3m Average total duration Fastest 3h 33m Onboard + 30m Additional time* | 4h 41m Average total duration 4h 11m Onboard + 30m Additional time* | 3h 3m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Donato Milanese to Florence Santa Maria Novella:
A bus is $14 (€12) less than a train for this route with tickets for a train from San Donato Milanese to Florence Santa Maria Novella costing on average $32 (€26).
Other travel options to Florence Santa Maria Novella take longer:
Bus takes on average 4h 11m.
Tickets start at around $32 (€26) compared to roughly $58 (€47) in fuel and tolls — a saving of about $26 (€21). The journey takes 3h 33m versus 3h 3m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for San Donato Milanese to Florence Santa Maria Novella trains for tomorrow, Monday, May 25. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:21 PM San Donato Milanese | 4h49 | 9:10 PM Florence Santa Maria Novella | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from San Donato Milanese to Florence Santa Maria Novella run on average 7 times per day, taking around 3h 33m. Cheap train tickets for this journey start at $23 (€19) but you can travel from only $12 (€10) by bus.
There are 2 trains per day. The earliest train runs at 04:40, the last at 16:21. The fastest train covers the 149 miles (241 km) distance in 4h 35m.
Distance 149 miles (241 km) |
Average train duration 3h 33m |
Cheapest ticket price $23 (€19) |
Trains per day 7 |
Direct trains 2 |
Fastest train 4h 35m |
First train 4:40 AM |
Last train 4:21 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sun |
Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.
World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. One of Florence’s essential art museums and often requires advance booking.
Best known for Michelangelo’s David, plus important Florentine paintings and sculpture. Extremely popular and commonly booked in advance.
Outstanding museum of original works from Florence Cathedral, Baptistery, and Giotto’s Bell Tower, including sculptures by Michelangelo and Donatello.
Florence’s monumental heart, surrounded by the cathedral, baptistery, and bell tower. Constantly lively and essential for first-time visitors.
Historic political square lined with sculptures and dominated by Palazzo Vecchio. One of the city’s most iconic public spaces.
The classic panoramic viewpoint over Florence, highly popular for sunset photos and sweeping skyline views.
Thick-cut T-bone steak from Chianina beef, grilled rare over coals. It is the city’s signature dish and a classic of Florentine cooking.
A hearty Tuscan bread and vegetable soup, usually made with cavolo nero, beans, and stale bread. It is one of Florence’s most traditional comfort foods.
Rustic tomato and bread soup flavored with garlic, basil, and olive oil. A beloved Tuscan staple with simple, local ingredients.
Established Michelin-starred restaurant offering refined Tuscan cuisine in an elegant contemporary setting not far from central Florence.
Historic, no-frills Florentine trattoria popular for traditional daily dishes, ribollita, and hearty meat plates in a classic local atmosphere.
Well-known traditional restaurant with a rustic dining room, famous for Tuscan antipasti and Bistecca Alla Fiorentina served in generous portions.
Moderate by Italian standards. Coffee and casual meals are reasonable, but hotels and tourist-area dining near the station cost more.
Service is often included or covered by coperto. Tipping is not required; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Florence Santa Maria Novella, Florence -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from San Donato Milanese to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

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