The cheapest and fastest trains from Lyon Part Dieu to Brussels-Central
Cheapest price
$182
Average price
$182
Fastest journey
3 h 51 m
Average duration
4 h 1 m
Trains per day
5
Distance
567 km
The best way to find a cheap train ticket from Lyon Part Dieu to Brussels-Central is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Part Dieu to Brussels-Central will cost around $182 if you buy it on the day, but the cheapest tickets can be found for only $182.
It's difficult to get from Lyon Part Dieu to Brussels-Central without transferring at least once.










Lyon Part Dieu - Brussels-CentralCompare TGV, TGV INOUI


Travel Information
Compare train, bus, and flight for Lyon Part Dieu to Brussels-Central
Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Brussels-Central among Omio's users. If you are prioritising price take the bus with prices starting from €17. For those with little time consider booking a flight which can get you there in 1h 20m. The ticket price range depends on the travel mode: a bus costs an average of €17, and a flight costs an average of €76.
Distance: 352 miles (567 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€161 Average price | €33 Average price Cheapest | €212 Average price |
4h 25m Average total duration 3h 55m Onboard + 30m Additional time* | 10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 4h 20m Average total duration Fastest 1h 20m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Lyon Part Dieu to Brussels-Central train times
The table below shows live departures for Lyon Part Dieu to Brussels-Central trains for today, Saturday, December 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:00 AM Lyon Part Dieu | 4h36 | 3:36 PM Brussels-Central | 1 transfer | |
![]() | 1:59 PM Lyon Part Dieu | 3h52 | 5:51 PM Brussels-Central | 1 transfer | |
![]() | 4:59 PM Lyon Part Dieu | 3h52 | 8:51 PM Brussels-Central | 1 transfer | |
![]() | 7:00 PM Lyon Part Dieu | 4h00 | 11:00 PM Brussels-Central | 1 transfer | |
| Sunday, December 21 | |||||
![]() | 8:25 AM Lyon Part Dieu | 3h54 | 12:19 PM Brussels-Central | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Lyon Part Dieu to Brussels-Central by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 20
Dec 23
Dec 24
Dec 28
Dec 29
Dec 30
Dec 31
Why should you book Lyon Part Dieu to Brussels-Central trains with Omio?
TGV as well as TGV INOUI offer trains services from Lyon Part Dieu to Brussels-Central. Omio is an official ticket reseller for all your travel options from Lyon Part Dieu to Brussels-Central.
Why book with Omio vs TGV?
- Compare with other providers: On Omio, you can not only buy tickets for TGV, but also compare tickets for the likes of TGV INOUI to find the best option for your trip from Lyon Part Dieu to Brussels-Central.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare TGV with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Brussels-Central.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While TGV tickets can be bought on TGV's website or third party sellers, Omio allows you to compare with the likes of TGV INOUI to help you choose the right option for your journey from Lyon Part Dieu to Brussels-Central.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon Part Dieu to Brussels-Central.
Journey information
Overview: Train from Lyon Part Dieu to Brussels-Central
Trains from Lyon Part Dieu to Brussels-Central run on average 4 times per day, taking around 3h 55m. Cheap train tickets for this journey start at $185 (€148) but you can travel from only $21 (€17) by bus.
There are 4 trains per day. The earliest train runs at 05:50, the last at 19:00. The fastest train covers the 352 miles (567 km) distance in 3h 44m.
Distance 352 miles (567 km) |
Average train duration 3h 55m |
Cheapest ticket price $185 (€148) |
Trains per day 4 |
Direct trains 4 |
Fastest train 3h 44m |
First train 05:50 |
Last train 19:00 |
Train companies: TGV, TGV INOUI from Lyon Part Dieu to Brussels-Central trainsTGV, TGV INOUI trains will get you between Lyon Part Dieu and Brussels-Central from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
TGV INOUI
FAQs: Trains from Lyon Part Dieu to Brussels-Central
Find answers to the most common questions about traveling from Lyon Part Dieu to Brussels-Central by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels-Central, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon Part Dieu to Brussels-Central
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
More options for your journey from Lyon Part Dieu to Brussels-Central
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