- Must visit
The Getty Center
Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.
Omio recommends booking the train as it is the most popular option from Depew, NY to Los Angeles, CA among Omio's users. If you are prioritising price take the flight with prices starting from $211. For those with little time consider booking a flight which can get you there in 10h 14m. The ticket price range depends on the travel mode: a flight costs an average of $211, and a train costs an average of $420.
Distance: 2202 miles (3545 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$420 Average price | $211 Average price Cheapest | $221 Average price | $517 Average price (fuel + tolls) |
54h 35m Average total duration 54h 5m Onboard + 30m Additional time* | 13h 14m Average total duration Fastest 10h 14m Onboard + 3h 0m Additional time* | 78h 0m Average total duration 77h 30m Onboard + 30m Additional time* | 37h 0m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Depew, NY to Los Angeles, CA:
A flight is $10 (€8) less than a bus for this route with tickets for a bus from Depew, NY to Los Angeles, CA costing on average $221 (€179).
A flight is $209 (€170) less than a train for this route with tickets for a train from Depew, NY to Los Angeles, CA costing on average $420 (€340).
Other travel options to Los Angeles, CA take longer:
Train takes on average 54h 5m.
Bus takes on average 77h 30m.
Tickets start at around $420 (€340) compared to roughly $517 (€419) in fuel and tolls — a saving of about $97 (€79). The journey takes 54h 5m versus 37h 0m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Trains from Depew, NY to Los Angeles, CA run on average 3 times per day, taking around 54h 5m. Cheap train tickets for this journey start at $420 (€340) but you can travel from only $211 (€171) by flight.
The earliest train runs at 17:19, the last at 22:00. The fastest train covers the 2202 miles (3545 km) distance in 79h 56m.
Distance 2202 miles (3545 km) |
Average train duration 54h 5m |
Cheapest ticket price $420 (€340) |
Trains per day 3 |
Fastest train 79h 56m |
First train 5:19 PM |
Last train 10:00 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Apr - Jun |
Best time to book 7 days |
Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.
Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.
The largest art museum in the western United States, known for broad global collections and the iconic Urban Light installation.
Popular contemporary art museum in Downtown Los Angeles with works by Kusama, Warhol, and other major postwar artists.
Vast urban park with trails, scenic overlooks, and access to major attractions; a classic Los Angeles outdoor destination.
Iconic oceanfront boardwalk area with classic California views and broad appeal for first-time visitors.
Famous beachfront promenade known for street culture, skate scenes, murals, and constant people-watching.
A Los Angeles classic of thinly sliced roast beef on a roll, served with rich jus for dipping. It is one of the city’s most iconic old-school sandwiches.
Street tacos are central to Los Angeles food culture, especially carne asada, al pastor, and grilled fish tacos served on corn tortillas with salsa, onion, and cilantro.
A signature Los Angeles meal shaped by Koreatown, featuring grilled marinated meats, banchan, and shared dining. The city is especially known for its strong Korean barbecue scene.
Acclaimed fine dining restaurant known for refined seafood tasting menus and elegant service. One of Los Angeles’s top special-occasion destinations.
Historic downtown institution famous for the French dip sandwich. Casual, old-school atmosphere and one of Los Angeles’s most iconic food stops.
Well-known Oaxacan restaurant celebrated for complex moles, tlayudas, and mezcal. Lively atmosphere and a landmark for regional Mexican cuisine in Los Angeles.
Los Angeles is expensive for visitors. Hotels, parking, and dining add up quickly, though casual food and some neighborhoods offer better value.
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected at fast-food spots.
Find answers to the most common questions about traveling from Depew, NY to Los Angeles, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

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