- Must visit
The Getty Center
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Omio recommends booking the train as it is the most popular option from Depew, NY to Los Angeles, CA among Omio's users. If you are prioritising price take the flight with prices starting from $210. For those with little time consider booking a flight which can get you there in 10h 14m. The ticket price range depends on the travel mode: a flight costs an average of $210, and a train costs an average of $418.
Distance: 2202 miles (3545 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$418 Average price | $220 Average price | $210 Average price Cheapest | $515 Average price (fuel + tolls) |
54h 35m Average total duration 54h 5m Onboard + 30m Additional time* | 78h 0m Average total duration 77h 30m Onboard + 30m Additional time* | 13h 14m Average total duration Fastest 10h 14m Onboard + 3h 0m Additional time* | 37h 0m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Depew, NY to Los Angeles, CA:
A flight is $10 less than a bus for this route with tickets for a bus from Depew, NY to Los Angeles, CA costing on average $220.
A flight is $208 less than a train for this route with tickets for a train from Depew, NY to Los Angeles, CA costing on average $418.
Other travel options to Los Angeles, CA take longer:
Train takes on average 54h 5m.
Bus takes on average 77h 30m.
Tickets start at around $418 compared to roughly $515 in fuel and tolls — a saving of about $97. The journey takes 54h 5m versus 37h 0m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Trains from Depew, NY to Los Angeles, CA run on average 3 times per day, taking around 54h 5m. Cheap train tickets for this journey start at $418 but you can travel from only $210 by flight.
The earliest train runs at 17:19, the last at 22:00. The fastest train covers the 2202 miles (3545 km) distance in 79h 56m.
Distance 2202 miles (3545 km) |
Average train duration 54h 5m |
Cheapest ticket price $418 |
Trains per day 3 |
Fastest train 79h 56m |
First train 5:19 PM |
Last train 10:00 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Apr - Jun |
Best time to book 7 days |
Discover the best of Los Angeles, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles, CA trip today.
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Major contemporary art museum in Downtown LA, known for broad collections, special shows, and bold architecture.
World-class encyclopedic museum on Wilshire Boulevard, famous for diverse collections and the Urban Light installation.
Legendary boulevard known for the Walk of Fame, theaters, neon, and classic Hollywood atmosphere mixed with tourist energy.
Lively beachside promenade with street performers, Muscle Beach, and easy access to the Venice Boardwalk scene.
Major urban park with trails, the observatory, picnic areas, and some of the best public views in Los Angeles.
A bacon-wrapped hot dog grilled on a street cart and topped with peppers, onions, mustard, ketchup, and mayo. A late-night Los Angeles street food classic.
A French dip sandwich of thin-sliced roast beef on a roll, often dipped in meat jus. Los Angeles claims the original and locals still debate the best version.
Double corn tortillas filled with stewed beef, birria broth, onions, and cilantro. A beloved Los Angeles Mexican staple, especially popular from trucks and taquerias.
Acclaimed fine-dining restaurant serving a seasonal California tasting menu. Refined, intimate, and one of Los Angeles's most respected special-occasion venues.
Legendary taqueria known for charcoal-grilled carne asada tacos. Casual, fast-paced, and widely considered one of Los Angeles's essential taco stops.
Historic downtown deli linked to the French dip. Old-school counter service and classic sandwiches in a landmark Los Angeles setting.
Los Angeles is pricier than many U.S. cities for hotels, dining, parking, and rides. Budget options exist, but tourist areas and transport costs raise daily spend.
Tip 18-20% in restaurants, 15-20% for taxis or rideshares, and $1-2 at cafes for counter service or coffee.
Find answers to the most common questions about traveling from Depew, NY to Los Angeles, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

Most Depew, NY to Los Angeles, CA trains use the Depew Amtrak Station to Union Station station pair. Use this guide to compare Depew, NY and Los Angeles, CA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Depew Amtrak Station is 2 km from Depew city centre. Public transport options include:
Depew Amtrak Station has practical services for this route, including Lockers, Parking, Taxis, Accessibility, WC, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Ticket office support is available at Depew Amtrak Station. Information desks are located in the main hall.
Luggage storage is available at Depew Amtrak Station. Lost and found is available at the station.
Available at Depew Amtrak Station: Parking, Taxis, WC.
Accessibility facilities are available at Depew Amtrak Station: Ramps, restrooms.
Union Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Traxx Restaurant, Union Station Cafe, Philippe The Original
Free. ATMs are available in the train station.
Ticket office support is available at Union Station. Information desks are located in the main hall.
Luggage storage is available at Union Station. Lost and found is available at the station.
Available at Union Station: Parking, Taxis, WC.
Available at Union Station: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Union Station: Elevators, restrooms.
Nearby hotels include DoubleTree by Hilton Los Angeles Downtown, Miyako Hotel Los Angeles, Omni Los Angeles Hotel at California Plaza.
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