- Must visit
Everson Museum Of Art
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
Omio recommends booking the train as it is the most popular option from Depew, NY to Syracuse, NY among Omio's users. If you are prioritising price take the train with prices starting from $30. For those with little time consider booking a train which can get you there in 2h 14m. The ticket price range depends on the travel mode: a train costs an average of $30, and a flight costs an average of $124.
Distance: 129 miles (208 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$31 Average price Cheapest | $342 Average price | $33 Average price | $29 Average price (fuel + tolls) |
2h 44m Average total duration Fastest 2h 14m Onboard + 30m Additional time* | 11h 0m Average total duration 8h 0m Onboard + 3h 0m Additional time* | 3h 18m Average total duration 2h 48m Onboard + 30m Additional time* | 2h 8m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Depew, NY to Syracuse, NY:
A train is $3 (€2) less than a bus for this route with tickets for a bus from Depew, NY to Syracuse, NY costing on average $33 (€27).
A train is $312 (€255) less than a flight for this route with tickets for a flight from Depew, NY to Syracuse, NY costing on average $342 (€280).
Other travel options to Syracuse, NY take longer:
Bus takes on average 2h 48m.
Flight takes on average 8h 0m.
Tickets start at around $31 (€25) compared to roughly $29 (€24) in fuel and tolls — a saving of about $-1.82 (€-1.49). The journey takes 2h 14m versus 2h 8m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Depew, NY to Syracuse, NY run on average 7 times per day, taking around 2h 14m. Cheap train tickets for this journey start at $30 (€25) if you book in advance.
There are 5 trains per day. The earliest train runs at 04:35, the last at 22:05. The fastest train covers the 129 miles (208 km) distance in 2h 10m.
Distance 129 miles (208 km) |
Average train duration 2h 14m |
Cheapest ticket price $30 (€25) |
Trains per day 7 |
Direct trains 5 |
Fastest train 2h 10m |
First train 4:35 AM |
Last train 10:05 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 3 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
A local history museum in the last remaining weighlock building in the United States, focusing on the Erie Canal’s impact on Syracuse and New York State.
A hands-on science museum in downtown Syracuse with interactive exhibits and a planetarium, popular with families and visitors interested in STEM.
Syracuse’s best-known historic district, filled with restored warehouses, lively streets, and a strong mix of shopping, architecture, and nightlife.
A popular waterfront recreation area with trails, lake views, and sunset spots that are frequently featured in local social media posts.
A central downtown square known for historic buildings, events, and seasonal programming, including its popular winter ice rink.
Small potatoes boiled in very salty water until the skins wrinkle, then served with melted butter. They are a signature Central New York dish with roots in the region's salt industry.
A spicy pasta dish with chicken, rigatoni, peppers, and a creamy tomato sauce. Though more closely tied to nearby Utica, it is widely loved across Central New York and commonly found in Syracuse.
A bakery-style rectangular pizza served at room temperature with thick crust, tomato sauce, and little or no cheese. It is a classic Upstate New York snack and party food.
A long-running Syracuse favorite known for handmade pasta, spicy hot tomato oil, and a lively downtown atmosphere.
An established Italian restaurant on the north side, appreciated for classic pasta dishes, warm service, and a cozy neighborhood feel.
A famous casual barbecue restaurant and roadhouse-style venue known for smoked meats, classic sides, and a bustling, iconic setting.
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and fine dining cost more during peak dates.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Depew, NY to Syracuse, NY by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

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