- Must visit
Everson Museum of Art
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Omio recommends booking the train as it is the most popular option from Depew, NY to Syracuse, NY among Omio's users. If you are prioritising price, take the train, with an average ticket price of $42 For those with little time, consider booking a train, which has an average total journey time of 2h 44m. Average ticket prices depend on the travel mode: a train costs an average of $42, while a flight costs an average of $817.
Distance: 129 miles (208 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$42 Average price Cheapest | $817 Average price | $42 Average price | $29 Average price (fuel + tolls) |
2h 44m Average total duration Fastest 2h 14m Onboard + 30m Additional time* | 5h 40m Average total duration 3h 40m Onboard + 2h 0m Additional time* | 3h 29m Average total duration 2h 59m Onboard + 30m Additional time* | 2h 8m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Depew, NY to Syracuse, NY:
A train is $0.31 less than a bus for this route with tickets for a bus from Depew, NY to Syracuse, NY costing on average $42.
A train is $775 less than a flight for this route with tickets for a flight from Depew, NY to Syracuse, NY costing on average $817.
Other travel options to Syracuse, NY take longer:
Bus takes on average 2h 59m.
Flight takes on average 3h 40m.
Tickets start at around $42 compared to roughly $29 in fuel and tolls — a saving of about $-12.66. The journey takes 2h 14m versus 2h 8m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Depew, NY to Syracuse, NY run on average 4 times per day, taking around 2h 14m. Cheap train tickets for this journey start at $30 if you book in advance.
There are 4 trains per day. The earliest train runs at 04:35, the last at 22:05. The fastest train covers the 129 miles (208 km) distance in 2h 4m.
Distance 129 miles (208 km) |
Average train duration 2h 14m |
Cheapest ticket price $30 |
Trains per day 4 |
Direct trains 4 |
Fastest train 2h 4m |
First train 4:35 AM |
Last train 10:05 PM |
Cheapest Month Mar |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 2 days |
Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.
Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.
Historic downtown square and year-round gathering place, known for festivals, fountains, and winter skating. A central stop for city atmosphere.
Scenic waterfront park with long trails, lake views, and birdlife. Popular for walking, cycling, and relaxing near Syracuse's restored shoreline.
Compact downtown district filled with galleries, murals, and restored warehouse buildings. Best explored on foot for arts culture and architecture.
Salt potatoes are small potatoes boiled in heavily salted water, creating a crusty skin and creamy center. They are a Central New York summer staple, often served with butter.
Chicken riggies is a spicy Utica pasta dish popular across Central New York, made with chicken, rigatoni, peppers, and a creamy tomato sauce.
Utica greens are escarole sautéed with hot peppers, garlic, breadcrumbs, and often prosciutto. This Italian American side is beloved throughout the Syracuse area.
Long running market cafe and bakery known for tomato pie, sandwiches, pastries, and a classic Syracuse neighborhood feel.
Established Italian restaurant known for homemade pasta, regional Italian American dishes, and a polished but welcoming atmosphere.
Upscale downtown dining with seasonal American cuisine, thoughtful plating, and a refined setting popular for special occasions.
Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Find answers to the most common questions about traveling from Depew, NY to Syracuse, NY by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Most Depew, NY to Syracuse, NY trains use the Depew Amtrak Station to Syracuse Station station pair, with some services arriving at New York State Fair. Use this guide to compare Depew, NY and Syracuse, NY train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Depew Amtrak Station is 2 km from Depew city centre. Public transport options include:
Depew Amtrak Station has practical services for this route, including Lockers, Parking, Taxis, Accessibility, WC, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Ticket office support is available at Depew Amtrak Station. Information desks are located in the main hall.
Luggage storage is available at Depew Amtrak Station. Lost and found is available at the station.
Available at Depew Amtrak Station: Parking, Taxis, WC.
Accessibility facilities are available at Depew Amtrak Station: Ramps, restrooms.
Syracuse Station is 3 km from Syracuse city centre. Public transport options include:
Syracuse Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Car Rental, Information Desk, and Luggage Carts.
Food options include: Dinosaur Bar-B-Que, The Mission Restaurant
Ticket office support is available at Syracuse Station. Information desks are located in the main hall.
Luggage storage is available at Syracuse Station. Lost and found is available at the station.
Available at Syracuse Station: Parking, Taxis, WC.
Available at Syracuse Station: Car Rental.
Accessibility facilities are available at Syracuse Station.
Nearby hotels include Embassy Suites by Hilton Syracuse, Comfort Inn & Suites Airport, Best Western Syracuse Downtown Hotel and Suites.
New York State Fair is 7 km from Syracuse city centre. Public transport options include:
New York State Fair has practical services for this route, including Accessibility.
Accessibility facilities are available at New York State Fair.
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