- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Flights from Atlanta, GA to Florence, SC depart on average 21 times per day, taking around 5h 10m. Cheap flight tickets for this journey start at $421 but you can travel from only $39 by bus.
The fastest flight covers the 266 miles (429 km) distance in 2h 32m. May is the cheapest month to fly.
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Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Atlanta, GA to Florence, SC.
Flights from Atlanta, GA to Florence, SC with American Airlines, psa airlines, and Republic Airlines. Flights with a stop available on this route with American Airlines, psa airlines, and Republic Airlines. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.
Find answers to the most common questions about traveling from Atlanta, GA to Florence, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Atlanta, GA to Florence, SC flights use the Hartsfield-Jackson International Airport to Florence Regional Airport airport pair. Use this guide to compare Atlanta, GA and Florence, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Hartsfield-Jackson International Airport is 1 km from Atlanta city centre. Public transport options include:
Hartsfield-Jackson International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are located in all concourses, offering a variety of cuisines including fast food, American, and intertiol options. Top picks include One Flew South and Paschal's.
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport, in all terminals and concourses.
Lost and found is available at the station.
Available at Hartsfield-Jackson International Airport: Parking, Taxis, WC.
Available at Hartsfield-Jackson International Airport: Car Rental.
Accessibility facilities are available at Hartsfield-Jackson International Airport: Elevators, ramps.
Nearby hotels include Several hotels within walking distance, including the Atlanta Airport Marriott Gateway and Reissance Atlanta Airport Gateway Hotel..
Florence Regional Airport is 3 km from Florence city centre. Public transport options include:
Florence Regional Airport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi is available throughout the terminal. ATMs are aTM available inside the terminal.
Ticket office support is available at Florence Regional Airport.
Available at Florence Regional Airport: Parking, Taxis, WC.
Accessibility facilities are available at Florence Regional Airport: Facilities are accessible to passengers with reduced mobility.
See which airports are used for flights between Atlanta, GA and Florence, SC, including airport details.