Journey information
Overview: Santiago to Brussels flight
Flights from Santiago to Brussels depart on average 49 times per day, taking around 15h 41m. Cheap flight tickets for this journey start at $643 (€511) if you book in advance.
The earliest flight runs at 00:20, the last at 23:55. The fastest flight covers the 7388 miles (11890 km) distance in 21h 35m. November is the cheapest month to fly.
Distance 7388 miles (11890 km) |
Average flight duration 15h 41m |
Cheapest ticket price $643 (€511) |
Flights per day 49 |
Fastest flight 21h 35m |
Cheapest month to travel November |
First flight 00:20 |
Last flight 23:55 |
The cheapest and fastest flights from Santiago to Brussels
Cheapest price
$742
Average price
$742
Fastest journey
17 h 20 m
Average duration
17 h 20 m
Flights per day
1
Distance
11890 km
The best way to find a cheap flight ticket from Santiago to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santiago to Brussels will cost around $742 if you buy it on the day, but the cheapest tickets can be found for only $742.
Of the 1 flights that leave Santiago for Brussels onThu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct flights cover the 11890 km distance in an average of 17 h 20 m but if you time it right, some flights will get you there in just 17 h 20 m .
On Thu, Feb 05 the longest flights will take 17 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Live departures
Santiago to Brussels flight times
The table below shows live departures for Santiago to Brussels flights for today, Wednesday, February 4. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
LA2430 · LA2468+ SN502 | 11:50 PM Santiago | 30h50 | 6:40 AM Brussels Airport | 2 transfers | |
| Thursday, February 5 | |||||
LA706+ SN3728 | 12:00 AM Santiago | 18h55 | 6:55 PM Brussels Airport | 1 transfer | |
LA706+ IB601 | 12:00 AM Santiago | 18h00 | 6:00 PM Brussels Airport | 1 transfer | |
LA706+ IB603 | 12:00 AM Santiago | 21h35 | 9:35 PM Brussels Airport | 1 transfer | |
IB6585+ IB603 | 12:00 AM Santiago | 21h35 | 9:35 PM Brussels Airport | 1 transfer | |
LA706+ LA1566 | 12:00 AM Santiago | 18h00 | 6:00 PM Brussels Airport | 1 transfer | |
LA706+ LA1544 | 12:00 AM Santiago | 21h35 | 9:35 PM Brussels Airport | 1 transfer | |
IB6585+ IB601 | 12:00 AM Santiago | 18h00 | 6:00 PM Brussels Airport | 1 transfer | |
LA532+ SN502 | 2:30 AM Santiago | 28h10 | 6:40 AM Brussels Airport | 1 transfer | |
LA5413 · LA1544 | 2:55 AM Santiago | 18h40 | 9:35 PM Brussels Airport | 1 transfer | |
IB114 · IB603 | 2:55 AM Santiago | 18h40 | 9:35 PM Brussels Airport | 1 transfer | |
![]() | 2:25 PM Santiago | 17h20 | 7:45 AM Brussels | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santiago to Brussels by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Why should you book Santiago to Brussels flights with Omio?
Why book with Omio vs LATAM Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for LATAM Airlines, but also compare tickets for the likes of Iberia to find the best option for your trip from Santiago to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Kayak, Edreams or Trip?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Iberia to find the best option for your trip from Santiago to Brussels.
Airlines: LATAM Airlines, Iberia from Santiago to BrusselsFind the best flights between Santiago to Brussels with Omio's travel partners LATAM Airlines, Iberia from $643 (€511). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
LATAM Airlines
Iberia
FAQs: Santiago to Brussels Flight
Find answers to the most common questions about traveling from Santiago to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Ommegang, a historical pageant celebrating the medieval heritage of Brussels
- Brussels Flower Carpet, a stunning floral display in the Grand Place every two years
- Brussels Jazz Marathon, a weekend of free jazz performances across the city
- Belgian Beer Weekend, a festival showcasing Belgium's rich beer culture with tastings and workshops.
- New Year's Day, a time for fresh beginnings and local celebrations
- Easter Monday, a public holiday with family gatherings and spring festivities
- Ascension Day, a day off for locals to enjoy the early summer weather
- National Day, celebrating Belgium's independence with parades and fireworks
- All Saints' Day, a day for remembrance and autumn reflections.
popular airports
Popular airports from Santiago to Brussels
- Free Wi-Fi available throughout the airport.
- Shops include duty-free and local Chilean products, located in both terminals.
- Parking available in several lots, approximately 1.7€ (CLP 1,500) per hour.
- Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby include Holiday Inn Santiago Airport, within walking distance.
- Showers available in VIP lounges; access may require a lounge pass or fee.
- Several lounges available, including LATAM and American Airlines lounges.
- Lost and Found located in the arrivals area.
- Car rental services available from major companies like Hertz and Avis.
- Bus Centropuerto, Pajaritos Station, 19 km
- Free Wi-Fi available throughout the airport.
- Shops located in Pier A and Pier B, includes Duty-Free and fashion stores.
- Parking available at P1, P2, and P3, approximately 4€ per hour.
- Available outside the terminal.
- Elevators, ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in Pier A and Pier B, includes Brussels Airlines and Diamond Lounges.
- Located in the arrivals area.
- Bus: 272, 471
- Train: IC, S2, S4, S5, S9
Most popular flights from Santiago
More options for your journey from Santiago to Brussels
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