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Journey information
Overview: Rome to Mytilene flight
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 763 miles (1228 km) |
Average flight duration 2h 56m |
Cheapest ticket price $125 (€102) |
Flights per day 5 |
Fastest flight 10h 30m |
Cheapest month to travel March |
First flight 08:15 |
Last flight 23:00 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Rome to Mytilene start from as low as $125 (€102) if booked well in advance.
- Standard Fares: Typically, trains cost $144 (€118) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Airlines: Aegean Airlines from Rome to MytileneFind the best flights between Rome to Mytilene with Omio's travel partners Aegean Airlines from $125 (€102). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Aegean Airlines
About
Aegean Airlines is the flag carrier of Greece and a leading airline in Southeastern Europe, connecting travelers to destinations across Europe, the Middle East, and North Africa. Operating from its main hubs in Athens and Thessaloniki, Aegean offers a modern fleet and high-quality service. Passengers can enjoy comfortable seating, complimentary snacks and drinks on most flights, and additional perks in Business Class such as lounge access, premium dining, and extra comfort. With affordable fares and strong regional connectivity, Aegean Airlines is a trusted choice for exploring Greece and beyond.
Luggage & cancellation policy
Average Duration
12h 50m
Cheapest Price
$190 (€155)
Aegean Airlines frequency
5 a day
Luggage included
1 carry-on bag (max 8kg, 56x45x25cm) and 1 personal item (max 40x20x25cm)
Additional luggage
23kg checked baggage, additional fees apply for extra weight
Cancellation Policy
Refundable tickets available with flex fare option, non-refundable tickets can be changed for a fee
Pregnant on board
Pregnant women can travel up to the 36th week without medical certificate, after that requires doctor's approval
Unaccompagned minor
Children aged 5-11 can travel unaccompanied with mandatory assistance service. Ages 12-17 optional assistance
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets allowed in cabin, max 8kg including carrier. Must be booked in advance
Entertaiment on board
FAQs: Rome to Mytilene Flight
Find answers to the most common questions about traveling from Rome to Mytilene by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Mytilene, this guide helps you travel smarter and with confidence.

Cheap plane tickets from Rome to Mytilene can start from as little as $190 (€155) when you book in advance. The average flight ticket price for Rome to Mytilene is $190 (€155); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Rome to Mytilene flight time is 12 h 50 min covering the 761 mile (1227 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The earliest flight from Rome to Mytilene leaves at 7: 20AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Rome to Mytilene leaves at 11: 00PM.
Take the Rome to Mytilene flight with Aegean Airlines. However, it's always good to check out all possible airlines for the route from Rome to Mytilene as there might be differences in the amenities they offer.
The cheapest month to travel from Rome to Mytilene by plane is January.
Yes, you can take a flight between Rome and Mytilene.
Since both Rome and Mytilene are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
There is a time difference of 1 h between Rome and Mytilene all year round.
The best events to attend in Mytilene include:
- Mytilene International Film Festival, a vibrant celebration of cinema featuring screenings, workshops, and discussions with filmmakers
- Ouzo Festival, an annual event dedicated to the famous local spirit with tastings, music, and cultural activities
- Mytilene Carnival, a lively festival filled with parades, costumes, and traditional Greek festivities.
The best holidays to experience in Mytilene include:
- Ochi Day, commemorative events and parades celebrating Greek history
- Easter, vibrant local traditions and beautiful spring weather
- Assumption of Mary, lively festivities and cultural celebrations throughout the city.
The best seasons to visit Mytilene are Spring or Fall. The best weather to explore Mytilene is during April-June or September-October.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e. G. 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs).
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from Rome to Mytilene
Rome
Mytilene
The major airport for departures in Rome is Rome Leonardo da Vinci Fiumicino Airport. Find all the information you need to know about services, amenities and connections at Rome Leonardo da Vinci Fiumicino Airport for your trip from Rome to Mytilene.
Amenities at airport
information
Distance to city center
3 kmCar connection
A91, Exit Fiumicino AeroportoWifi
- Free Wi-Fi available throughout the airport for an unlimited duration.
Shopping
- Shops are located in all terminals, featuring brands like Gucci and Duty-Free stores.
Parking
- Parking available with options including short-term and long-term parking, approximately 3€ per hour.
Taxis
- Available outside the terminal.
Accessibility
- Ramps, assistance, toilets.
WC
- Available throughout the airport.
Shower
- Yes
Lounge
- Lounges available, including the Plaza Premium Lounge, with amenities like food, drinks, and showers.
Lost and Found Office
- Located in Terminal 3, with a dedicated office for inquiries.
Public transit options for Rome Leonardo da Vinci Fiumicino Airport
- Bus: Terravision, SIT Bus Shuttle
- Train: Leonardo Express, FL1
The major airport for arrivals in Mytilene is Mytilene International Airport. Find all the information you need to know about services, amenities and connections at Mytilene International Airport for your journey to Mytilene from Rome.
Amenities at airport
information
Distance to city center
3 kmCar connection
Epar.Od. Mytilinis - Thermi, Exit MytileneWifi
- Free Wi-Fi available throughout the airport.
Shopping
- A few shops, including a duty-free shop in the terminal.
Parking
- Parking available near the terminal, approximately 1€ per hour.
Taxis
- Available outside the terminal.
Accessibility
- Ramps, toilets.
WC
- Available throughout the airport.
Lost and Found Office
- Located at the information desk.
Public transit options for Mytilene International Airport
- Bus: 6
- Bus: 8
More options for your journey from Rome to Mytilene
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