- Must visit
Art Institute Of Chicago
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
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Journey information
Overview: Des Moines, IA to Chicago, IL flight
USAUSA
Flights from Des Moines, IA to Chicago, IL depart on average 33 times per day, taking around 1h 34m. Cheap flight tickets for this journey start at $90 (€74) but you can travel from only $41 (€34) by bus.
There are 4 flights per day. The earliest flight runs at 00:02, the last at 23:55. The fastest flight covers the 307 miles (495 km) distance in 1h 29m. August is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $41 (€34)
Distance 307 miles (495 km) |
Average flight duration 1h 34m |
Cheapest ticket price $90 (€74) |
Flights per day 33 |
Direct flights 4 |
Fastest flight 1h 29m |
First flight 12:02 AM |
Last flight 11:55 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $41 (€34)
The cheapest and fastest flights from Des Moines, IA to Chicago, IL
Showing times and prices for Jul 02
Cheapest price
$139
Average price
$301
Fastest journey
1 h 29 m
Average duration
1 h 33 m
Flights per day
5
Distance
495 km
Cheap tickets
The best way to find a cheap flight ticket from Des Moines, IA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Chicago, IL will cost around $301 if you buy it on the day, but the cheapest tickets can be found for only $139.
Fast flights
Of the 5 flights that leave Des Moines, IA for Chicago, IL onThu, Jul 02, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 02 the direct flights cover the 495 km distance in an average of 1 h 33 m but if you time it right, some flights will get you there in just 1 h 29 m .
On Thu, Jul 02 the longest flights will take 1 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
10:00 AM1h29Des Moines, IA11:29 AMChicago, IL$1391One-way0 transfers- 1:56 PM1h40Des Moines, IA3:36 PMChicago, IL$1521One-way0 transfers
- 6:37 PM1h31Des Moines, IA8:08 PMChicago, IL$3551One-way0 transfers
8:21 PM1h32Des Moines, IA9:53 PMChicago, IL$3731One-way0 transfers- 12:44 AM1h35Des Moines, IA2:19 AMChicago, IL$4881One-way0 transfers
- 10:00 AM1h29Des Moines, IA11:29 AMChicago, IL$1391One-way0 transfers
- 6:37 PM1h31Des Moines, IA8:08 PMChicago, IL$3551One-way0 transfers
- 8:21 PM1h32Des Moines, IA9:53 PMChicago, IL$3731One-way0 transfers
- 12:44 AM1h35Des Moines, IA2:19 AMChicago, IL$4881One-way0 transfers
- 1:56 PM1h40Des Moines, IA3:36 PMChicago, IL$1521One-way0 transfers
Travel Information
Compare bus and flight for Des Moines, IA to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a flight which can get you there in 1h 34m. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $90.
Distance: 307 miles (495 km)
Compare flight with
| Flight | Most popular Bus | Driving |
|---|---|---|
$287 Average price | $77 Average price Cheapest | $76 Average price (fuel + tolls) |
4h 34m Average total duration Fastest 1h 34m Onboard + 3h 0m Additional time* | 8h 28m Average total duration 7h 58m Onboard + 30m Additional time* | 5h 12m Average total duration (door-to-door) |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Des Moines, IA to Chicago, IL is a bus with an average price of $77 (€63).
This is compared to other travel options from Des Moines, IA to Chicago, IL:
A bus is $210 (€173) less than a flight for this route with tickets for a flight from Des Moines, IA to Chicago, IL costing on average $287 (€236).
The fastest way to travel from Des Moines, IA to Chicago, IL is by flight with an average journey time of 1h 34m.
Other travel options to Chicago, IL take longer:
Bus takes on average 7h 58m.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Chicago, IL including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Chicago, IL among Omio's users.
Live departures
Des Moines, IA to Chicago, IL flight times
The table below shows live departures for Des Moines, IA to Chicago, IL flights for today, Wednesday, July 1. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:30 PM Des Moines, IA | 10h22 | 4:52 AM Chicago, IL | 0 transfersDirect | |
| 8:21 PM Des Moines, IA | 1h32 | 9:53 PM Chicago, IL | 0 transfersDirect | |
| Thursday, July 2 | |||||
| 12:44 AM Des Moines, IA | 1h35 | 2:19 AM Chicago, IL | 0 transfersDirect | |
| 10:00 AM Des Moines, IA | 1h29 | 11:29 AM Chicago, IL | 0 transfersDirect | |
| 1:56 PM Des Moines, IA | 1h40 | 3:36 PM Chicago, IL | 0 transfersDirect | |
Find all the dates and times for this journey
How far in advance should I book flight tickets from Des Moines, IA to Chicago, IL?
The best time to book your flight from Des Moines, IA to Chicago, IL is 42 days before departure. See how prices for flights change on the Des Moines, IA to Chicago, IL route.
Prices are for one-way tickets for one passenger from Des Moines, IA to Chicago, IL per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your flight from Des Moines, IA to Chicago, IL.
Flights
from $253Compare prices and tickets Des Moines, IA to Chicago, IL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Des Moines, IA to Chicago, IL flights with Omio?
United as well as skywest airlines or Republic Airlines offer flights services from Des Moines, IA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Chicago, IL.
Why book with Omio vs United?
- Compare with other providers: On Omio, you can not only buy tickets for United, but also compare tickets for the likes of skywest airlines or Republic Airlines to find the best option for your trip from Des Moines, IA to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare United with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Chicago, IL.
Why book with Omio over Kayak, Skyscanner or Trip?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Chicago, IL.
Airlines: United, skywest airlines, Republic Airlines from Des Moines, IA to Chicago, ILFind the best flights between Des Moines, IA to Chicago, IL with Omio's travel partners United, skywest airlines, Republic Airlines from $41 (€34). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
United
About
United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.
Luggage & cancellation policy
Average Duration
1h 32m
Cheapest Price
$241 (€199)
United frequency
32 a day
Luggage included
Carry-on baggage allowance is 7kg total (2 pieces max. ) for both Choice and Flex fares on United Airlines and Virgin Australia flights.
Additional luggage
Excess baggage fees apply for additional checked luggage beyond the standard allowance.
Luggage storage
Both airlines provide checked baggage services for storing luggage during flights.
Cancellation Policy
Cancellation fees apply per person, per booking, with specific fees for different fare types.
Refund
Not applicable to flights; however, full refunds are available if flights are canceled by the airline.
Pregnant on board
Pregnant passengers are permitted to travel, with specific guidelines and medical certificates required after a certain gestational period.
Unaccompagned minor
Unaccompanied minors are permitted to travel, with specific age restrictions and services provided.
Amenities on board the airplane
Wifi
Food sold onboard
Meals and snacks are included on international flights operated by United Airlines and Virgin Australia.
Seat reservation
Seat selection may incur additional fees, depending on the fare type and airline.
Toilets
USB plugs
Accessibility
United Airlines and Virgin Australia offer services to and within Australia, providing accessible travel options for passengers with mobility needs.
Bikes
Both airlines permit bicycles onboard, with specific guidelines and fees.
Pets
United Airlines and Virgin Australia allow pets onboard, subject to specific policies and fees.
skywest airlines
About
SkyWest Airlines is a major North American regional airline headquartered in St. George, Utah. It operates flights for larger carriers such as Alaska Airlines (as Alaska SkyWest), American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express). SkyWest is the largest regional airline in North America by fleet size, passengers carried, and destinations served. The airline connects passengers to over 250 destinations across the United States, Canada, and Mexico, primarily linking smaller airports to major airline hubs. SkyWest's fleet consists of regional jets, including the Bombardier CRJ series and Embraer 175 aircraft.
Luggage & cancellation policy
skywest airlines frequency
2 a day
Luggage included
One carry-on bag and one personal item are allowed for free.
Additional luggage
Additional luggage can be purchased, and fees apply for excess, oversized, or overweight baggage.
Cancellation Policy
If canceled within 24 hours of purchase, a full refund is possible, provided the departure is at least 7 days away; after 24 hours, fees range from $100 to $500.
Refund
If SkyWest Airlines cancels a flight, passengers are eligible for a full refund.
Pregnant on board
Being pregnant on board is allowed, but specific policies may depend on the partner airline.
Unaccompagned minor
Children aged 5-14 can travel alone using the unaccompanied minor service, which includes airport escort and supervision.
Amenities on board the airplane
Seat reservation
Toilets
Accessibility
SkyWest Airlines complies with all provisions of the Air Carrier Access Act and accommodates customers with special needs.
Bikes
Bicycles can be checked in but may incur additional fees and must be properly packed.
Pets
Small pets like cats and dogs are allowed in the cabin for a fee, with restrictions on pet and carrier size.
Republic Airlines
About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Duration
1h 46m
Cheapest Price
$229 (€189)
Republic Airlines frequency
3 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.
Complete guide to Chicago
Things to do in Chicago
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
- Must visit
Field Museum
A top natural history museum known for Sue the T. rex, ancient cultures, fossils, and broad science collections.
- Must visit
Museum Of Science And Industry
A large hands-on science museum with a German submarine, space exhibits, and interactive engineering displays.
- Must visit
Millennium Park
Chicago’s signature downtown park, home to Cloud Gate, gardens, public art, and major seasonal events.
- Must visit
The Magnificent Mile
The city’s best-known avenue for architecture, shopping, and bustling urban energy along North Michigan Avenue.
- Must visit
Chicago Riverwalk
A popular pedestrian waterfront with excellent skyline views, bridges, and easy access to boat architecture tours.
Chicago-Style Deep-Dish Pizza
A thick, buttery crust pizza baked in a deep pan with layers of cheese, toppings, and chunky tomato sauce. It is one of Chicago’s most iconic and debated local specialties.
Chicago-Style Hot Dog
An all-beef hot dog on a poppy seed bun topped with yellow mustard, relish, onions, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food served without ketchup.
Italian Beef Sandwich
Thinly sliced seasoned roast beef piled onto an Italian roll, often dipped in its juices and topped with sweet peppers or giardiniera. It is a defining working-class Chicago sandwich.
Alinea
Chicago’s world-famous fine-dining restaurant known for highly creative tasting menus and theatrical presentation. It offers one of the city’s most celebrated upscale dining experiences.
Ricobene's
A beloved casual institution best known for breaded steak sandwiches and hearty Italian-American comfort food. It has a loyal local following and an old-school atmosphere.
Lou Malnati's Pizzeria
A legendary Chicago chain celebrated for buttery-crust deep-dish pizza and a classic casual atmosphere. One of the city’s best-known places to try this signature dish.
United States Dollar
Chicago is pricey for hotels and dining, but budget eats and public transit help keep daily costs manageable.
Average meal costs
- Budget
- USD 10-18 for fast food or casual takeout.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 90+ per person before drinks and tax.
- Coffee
- USD 4-7 for a regular coffee or latte.
Tipping culture
Tip 18-20% at restaurants; 15-20% for taxis and rideshares; USD 1-2 per drink at bars; USD 1-2 per bag for bellhops; USD 2-5 per night for housekeeping.
FAQs: Des Moines, IA to Chicago, IL Flight
Find answers to the most common questions about traveling from Des Moines, IA to Chicago, IL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Des Moines, IA to Chicago, IL can start from as little as $90 (€74) when you book in advance. The average flight ticket price for Des Moines, IA to Chicago, IL is $287 (€236) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Des Moines, IA to Chicago, IL is 1h 29m to travel the 307 miles (495 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Des Moines, IA to Chicago, IL leaves at 12:02 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Des Moines, IA to Chicago, IL leaves at 11:55 PM.
Yes, there are 4 direct flights a day from Des Moines, IA to Chicago, IL with United, skywest airlines, Republic Airlines. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Des Moines, IA to Chicago, IL, you can count on United, skywest airlines, Republic Airlines for the best way to get you to Chicago, IL. You can also check all possible airlines who offer a service between Des Moines, IA and Chicago, IL and compare the amenities they offer before buying a plane ticket.
The cheapest month for a flight from Des Moines, IA to Chicago, IL is August.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Chicago, IL including taking a bus and flight.
Since neither Des Moines, IA nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Des Moines, IA and Chicago, IL.
The best events to attend in Chicago, IL include:
- Chicago Air and Water Show, an exhilarating display of military and civilian aircraft performing daring maneuvers over Lake Michigan
- Lollapalooza, a massive music festival featuring top artists across multiple genres in Grant Park
- Chicago Gourmet, a premier culinary event celebrating the city's vibrant food scene with tastings, cooking demonstrations, and wine pairings.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best holidays to experience in Chicago, IL include:
- Memorial Day, the unofficial start of summer with vibrant outdoor activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a lively atmosphere with various festivals and pleasant weather.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
The best season to visit Chicago, IL is Spring or Summer. The best weather to explore Chicago, IL is during May-September.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Chicago, IL among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from Des Moines, IA to Chicago, IL
Most Des Moines, IA to Chicago, IL flights use the Des Moines International Airport to O'Hare International Airport airport pair. Use this guide to compare Des Moines, IA and Chicago, IL airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in Des Moines
Arrival airports in Chicago
Des Moines International Airport (DSM)
City-centre transport
Getting to Des Moines International Airport from Des Moines city centre
Bus8 · 14m · $1
Which Chicago, IL airport do flights from Des Moines, IA arrive at?
Flights from Des Moines, IA to Chicago, IL arrive at O'Hare International Airport. O'Hare International Airport is 2 miles (4 km) from Chicago, IL city centre.
O'Hare International Airport (ORD)10000 W O'Hare Ave, Chicago, IL 60666, USA
City-centre transport
Getting to O'Hare International Airport from Chicago city centre
O'Hare International Airport is 3 km from Chicago city centre. Public transport options include:
SubwayBlue Line · 1h 7m · $6 · every ~23 min
O'Hare International Airport airport facilities and services
O'Hare International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located throughout all terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at O'Hare International Airport: Parking, Taxis, WC.
Bike and car services
Available at O'Hare International Airport: Car Rental.
Accessibility
Accessibility facilities are available at O'Hare International Airport: Elevators, ramps, toilets.
Shops, hotels and contact
Nearby hotels include Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby..
Most popular flights from Des Moines, IA
More options for your journey from Des Moines, IA to Chicago, IL
Here are some other resources that might have the information you need
Most popular flights to and from Chicago, IL and Des Moines, IA
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