The cheapest and fastest buses from Syracuse, NY to Portland, ME
Cheapest price
$86
Average price
$100
Fastest journey
9 h 30 m
Average duration
9 h 55 m
Buses per day
2
Distance
481 km
The best way to find a cheap bus ticket from Syracuse, NY to Portland, ME is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Portland, ME will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $86.
It's difficult to get from Syracuse, NY to Portland, ME without transferring at least once.




Travel Information
Compare bus, train, and flight for Syracuse, NY to Portland, ME
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Portland, ME among Omio's users. If you are prioritising price take the bus with prices starting from $120. For those with little time consider booking a flight which can get you there in 4h 0m. The ticket price range depends on the travel mode: a bus costs an average of $120, and a flight costs an average of $392.
Distance: 298 miles (481 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$120 Average price Cheapest | $392 Average price | $299 Average price |
10h 25m Average total duration 9h 55m Onboard + 30m Additional time* | 7h 0m Average total duration Fastest 4h 0m Onboard + 3h 0m Additional time* | 16h 9m Average total duration 15h 39m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Syracuse, NY to Portland, ME bus times
The table below shows live departures for Syracuse, NY to Portland, ME buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:50 AM Syracuse, NY | 10h20 | 5:10 PM Portland, ME | 1 transfer | |
![]() | 3:55 PM Syracuse, NY | 9h30 | 1:25 AM Portland, ME | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to Portland, ME by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Syracuse, NY to Portland, ME buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Syracuse, NY to Portland, ME.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Syracuse, NY to Portland, ME.
Journey information
Overview: Bus from Syracuse, NY to Portland, ME
Buses from Syracuse, NY to Portland, ME run on average 3 times per day, taking around 9h 55m. Cheap bus tickets for this journey start at $120 (€97) if you book in advance.
The earliest bus runs at 06:50, the last at 21:00. The fastest bus covers the 298 miles (481 km) distance in 14h 0m.
Distance 298 miles (481 km) |
Average bus duration 9h 55m |
Cheapest ticket price $120 (€97) |
Buses per day 3 |
Fastest bus 14h 0m |
First bus 06:50 |
Last bus 21:00 |
Cheapest month Sep |
Cheapest day Tue |
High season Oct - Dec |
Low season Apr - Jun |
Best day to book ahead 1 day |
Bus providers: Greyhound from Syracuse, NY to Portland, MEYou can travel by bus between Syracuse, NY to Portland, ME with Greyhound for as low as $120 (€97). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Syracuse, NY to Portland, ME
Find answers to the most common questions about traveling from Syracuse, NY to Portland, ME by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, ME, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Portland Head Light, a historic lighthouse offering scenic ocean views and a museum in Fort Williams Park
- Old Port, a vibrant district with cobblestone streets, boutiques, and seafood restaurants
- Eastern Promenade, a waterfront park with trails, picnic areas, and panoramic views of Casco Bay
- Portland Museum of Art, featuring a diverse collection of American and European artworks
- Victoria Mansion, an ornate 19th-century home showcasing period architecture and furnishings.
- Enjoy a craft beer tour, sampling local brews from Portland's renowned breweries
- Take a scenic ferry ride to the nearby Casco Bay Islands
- Visit the Children's Museum & Theatre of Maine for interactive exhibits and performances
- Attend a live performance at the State Theatre, a historic venue hosting concerts and events
- Explore the Maine Narrow Gauge Railroad Co. & Museum, offering train rides and exhibits on Maine's rail history.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Syracuse, NY to Portland, ME
Most popular bus connections from Syracuse, NY
More options for your journey from Syracuse, NY to Portland, ME
Here are some other resources that might have the information you need
