- Must visit
National Museum of Underwater Archaeology (ARQVA)
Spain’s flagship museum for underwater archaeology, with Phoenician, Roman, and shipwreck finds from the Mediterranean. A top cultural stop on Cartagena’s waterfront.
Cheapest price
$87
Average price
$87
Fastest journey
14 h 45 m
Average duration
14 h 45 m
Buses per day
2
Distance
694 km
The best way to find a cheap bus ticket from Santander to Cartagena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Cartagena will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $87.
Of the 2 buses that leave Santander for Cartagena on Sun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 694 km distance in an average of 14 h 45 m but if you time it right, some buses will get you there in just 14 h 45 m .
On Sun, Jun 21 the slowest buses will take 14 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Santander to Cartagena among Omio's users. If you are prioritising price take the bus with prices starting from $84. For those with little time consider booking a flight which can get you there in 2h 25m. The ticket price range depends on the travel mode: a bus costs an average of $84, and a flight costs an average of $33.
Distance: 431 miles (694 km)
Most popular Bus | Flight |
|---|---|
$88 Average price Cheapest | $212 Average price |
12h 59m Average total duration 12h 29m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
This is compared to other travel options from Santander to Cartagena:
A bus is $124 (€102) less than a flight for this route with tickets for a flight from Santander to Cartagena costing on average $212 (€174).
Other travel options to Cartagena take longer:
Train takes on average 10h 37m.
Bus takes on average 12h 29m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Alsa | Departure Time 12:45AM | Arrival Time 01:50PM | Duration 13h05 | Departure days Wed | Cheapest price $88 |
Operator Alsa | Departure Time 01:00AM | Arrival Time 01:15PM | Duration 12h15 | Departure days Wed | Cheapest price $83 |
Operator Bilman Bus | Departure Time 04:15AM | Arrival Time 07:00PM | Duration 14h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $87 |
Operator Bilman Bus | Departure Time 05:15AM | Arrival Time 08:00PM | Duration 14h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $84 |
Operator Bilman Bus | Departure Time 06:15AM | Arrival Time 09:00PM | Duration 14h45 | Departure days Wed | Cheapest price $87 |
Operator Alsa | Departure Time 08:00AM | Arrival Time 09:50PM | Duration 13h50 | Departure days Wed | Cheapest price $89 |
Operator Alsa | Departure Time 10:30AM | Arrival Time 05:50AM | Duration 19h20 | Departure days Wed | Cheapest price $101 |
Operator Alsa | Departure Time 12:00PM | Arrival Time 05:50AM | Duration 17h50 | Departure days Wed | Cheapest price $95 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 05:50AM | Duration 14h20 | Departure days Wed | Cheapest price $119 |
Operator Alsa | Departure Time 04:00PM | Arrival Time 05:50AM | Duration 13h50 | Departure days Wed | Cheapest price $96 |
The table below shows live departures for Santander to Cartagena buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:15 AM Santander | 14h45 | 7:00 PM Cartagena | 0 transfersDirect | |
![]() | 5:15 AM Santander | 14h45 | 8:00 PM Cartagena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santander to Cartagena run on average 1 times per day, taking around 12h 29m. Cheap bus tickets for this journey start at $84 (€69) but you can travel from only $33 (€27) by flight.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 16:00. The fastest bus covers the 431 miles (694 km) distance in 14h 45m.
Distance 431 miles (694 km) |
Average bus duration 12h 29m |
Cheapest ticket price $84 (€69) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 14h 45m |
First bus 12:45 AM |
Last bus 4:00 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 1 day |
Discover the best of Cartagena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cartagena trip today.
Spain’s flagship museum for underwater archaeology, with Phoenician, Roman, and shipwreck finds from the Mediterranean. A top cultural stop on Cartagena’s waterfront.
Museum and access complex for Cartagena’s spectacular Roman theatre, combining archaeological galleries with the restored ancient performance space.
A naval history museum with ship models, maritime collections, and the well-known Isaac Peral submarine exhibit, reflecting the city’s strong military port identity.
Cartagena’s principal historic shopping street, lined with Modernist architecture, balconies, and some of the city’s most photographed façades.
The regenerated waterfront promenade with marina views, cruise activity, museums, and easy access to several of the city’s top attractions.
The grand square by the city hall and port, ideal for appreciating Cartagena’s civic architecture and starting a walk through the old centre.
The area’s signature rice dish, cooked in fish stock with ñora pepper and traditionally served with fish and alioli. It is closely tied to nearby Mar Menor fishing culture.
A hearty stew of dried broad beans simmered with ham, chorizo and spices. It is a classic regional tapa in Cartagena and Murcia.
A very Murcian tapa made with a rusks-style bread ring topped with Russian salad and an anchovy. It is one of the most typical bar snacks in Cartagena.
A Michelin-starred restaurant led by chef María Gómez, known for refined contemporary cooking rooted in Cartagena and Murcia products. Elegant but welcoming atmosphere.
A famous old-school tapas bar known for authentic local snacks, marinera-style tapas and a bustling informal atmosphere. A strong choice for traditional Cartagena flavors.
An established traditional restaurant and tapas spot popular for Murcian dishes, seafood and hearty local specialties. Lively, classic dining room.
Moderate by Spanish standards. Meals and coffee are reasonable, while tourist-area dining and summer stays cost more.
Tipping is modest. Round up or leave 5-10% in restaurants for good service. Small change for cafes is enough. Taxis are usually rounded up; hotel tips are optional.
Official public transport app
Cartagena, Estación de Autobuses -> Cartagena City Center
Find answers to the most common questions about traveling from Santander to Cartagena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cartagena, this guide helps you travel smarter and with confidence.

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