- Must visit
Acquario Laguna di Lesina
Town museum dedicated to the lagoon ecosystem, with aquariums and exhibits that explain Lesina’s fishing culture and natural environment.
Omio recommends booking the bus as it is the most popular option from San Donato Milanese to Lesina among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €67 For those with little time, consider booking a flight, which has an average total journey time of 3h 22m. Average ticket prices depend on the travel mode: a bus costs an average of €67, while a flight costs an average of €107.
Distance: 390 miles (629 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€67 Average price Cheapest | €98 Average price | €107 Average price | €150 Average price (fuel + tolls) |
9h 44m Average total duration 9h 14m Onboard + 30m Additional time* | 7h 35m Average total duration 7h 5m Onboard + 30m Additional time* | 3h 22m Average total duration Fastest 1h 22m Onboard + 2h 0m Additional time* | 6h 23m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Donato Milanese to Lesina:
A bus is €31 less than a train for this route with tickets for a train from San Donato Milanese to Lesina costing on average €98.
A bus is €40 less than a flight for this route with tickets for a flight from San Donato Milanese to Lesina costing on average €107.
Other travel options to Lesina take longer:
Train takes on average 7h 5m.
Bus takes on average 9h 14m.
Tickets start at around €67 compared to roughly €150 in fuel and tolls — a saving of about €83. The journey takes 9h 14m versus 6h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Marino Autolinee, Itabus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 07:05PM | Arrival Time 03:55AM | Duration 8h50 | Departure days Thu | Cheapest price €30 |
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Donato Milanese to Lesina run on average 4 times per day, taking around 9h 14m. Cheap bus tickets for this journey start at €40 but you can travel from only €28 by flight.
There are 3 buses per day. The earliest bus runs at 07:45, the last at 22:51. The fastest bus covers the 390 miles (629 km) distance in 8h 15m.
Distance 390 miles (629 km) |
Average bus duration 9h 14m |
Cheapest ticket price €40 |
Buses per day 4 |
Direct buses 3 |
Fastest bus 8h 15m |
First bus 7:45 AM |
Last bus 10:51 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 3 days |
Discover the best of Lesina — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lesina trip today.
Town museum dedicated to the lagoon ecosystem, with aquariums and exhibits that explain Lesina’s fishing culture and natural environment.
Visitor museum inside the protected area, presenting wetlands, birds, and local habitats through educational displays and nature interpretation.
Small local exhibition space focused on Lesina’s history, traditions, and lagoon culture; a useful stop for context before exploring the area.
Scenic waterfront promenade along Lake Lesina, ideal for sunset walks, birdwatching views, and an easy introduction to the town’s lagoon setting.
Protected wetland area famous for birdlife, fishing traditions, and broad water views; best explored for nature, photography, and local atmosphere.
Main town square and social hub, surrounded by everyday civic life and useful as a starting point for walking through central Lesina.
Find answers to the most common questions about traveling from San Donato Milanese to Lesina by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lesina, this guide helps you travel smarter and with confidence.

Most San Donato Milanese to Lesina buses use the Milano, San Donato - Settore B (Viale Giuseppe Impastato) to Lesina, Corso Vittorio Emanuele / Via G. Leopardi station pair. Use this guide to compare San Donato Milanese and Lesina bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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