- Must visit
National Cowboy & Western Heritage Museum
Leading museum on the American West, Native art, and frontier history, with excellent galleries and major rotating exhibitions.
Cheapest price
$77
Average price
$81
Fastest journey
9 h 35 m
Average duration
11 h 27 m
Buses per day
3
Distance
678 km
The best way to find a cheap bus ticket from San Antonio, TX to Oklahoma City, OK is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Oklahoma City, OK will cost around $81 if you buy it on the day, but the cheapest tickets can be found for only $77.
It's difficult to get from San Antonio, TX to Oklahoma City, OK without transferring at least once.
·
+
·
·
·
+
Omio recommends booking the train as it is the most popular option from San Antonio, TX to Oklahoma City, OK among Omio's users. If you are prioritising price take the train with prices starting from $57. For those with little time consider booking a flight which can get you there in 2h 21m. The ticket price range depends on the travel mode: a train costs an average of $57, and a flight costs an average of $137.
Distance: 421 miles (678 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$149 Average price | $83 Average price Cheapest | $252 Average price |
11h 31m Average total duration 11h 1m Onboard + 30m Additional time* | 11h 42m Average total duration 11h 12m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Oklahoma City, OK:
A train is $66 (€55) less than a bus for this route with tickets for a bus from San Antonio, TX to Oklahoma City, OK costing on average $149 (€123).
A train is $169 (€139) less than a flight for this route with tickets for a flight from San Antonio, TX to Oklahoma City, OK costing on average $252 (€208).
Other travel options to Oklahoma City, OK take longer:
Bus takes on average 11h 1m.
Train takes on average 11h 12m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 11:05AM | Duration 9h35 | Departure days Everyday | Cheapest price $79 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 07:45PM | Duration 12h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 07:45PM | Duration 12h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 11:55PM | Duration 11h20 | Departure days Everyday | Cheapest price $77 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 10:25AM | Duration 13h25 | Departure days Wed, Thu | Cheapest price $78 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 10:25AM | Duration 12h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $86 |
The table below shows live departures for San Antonio, TX to Oklahoma City, OK buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 11h20 | 11:55 PM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 1 transfer | |
FlixBus+![]() | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 12h30 | 10:25 AM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 1 transfer | |
| Wednesday, July 15 | |||||
· | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 9h35 | 11:05 AM Oklahoma City, E Reno Ave (Greyhound Bus Station), OK | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Oklahoma City, OK run on average 4 times per day, taking around 11h 1m. Cheap bus tickets for this journey start at $69 (€57) but you can travel from only $57 (€47) by train.
The earliest bus runs at 01:30, the last at 21:45. The fastest bus covers the 421 miles (678 km) distance in 11h 15m.
Distance 421 miles (678 km) |
Average bus duration 11h 1m |
Cheapest ticket price $69 (€57) |
Buses per day 4 |
Fastest bus 11h 15m |
First bus 1:30 AM |
Last bus 9:45 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 1 day |
Discover the best of Oklahoma City — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Oklahoma City trip today.
Leading museum on the American West, Native art, and frontier history, with excellent galleries and major rotating exhibitions.
Powerful museum interpreting the 1995 bombing through artifacts, oral histories, and immersive exhibits in the former Journal Record Building.
Large modern art museum known for Chihuly glass, international works, film programming, and a central downtown location.
Lively entertainment district with canal walks, public art, nightlife, and easy access to sports, museums, and downtown attractions.
Large downtown urban park with gardens, playgrounds, lawns, lake views, and regular events beside major civic attractions.
Canal-side district blending old warehouses, modern development, riverside trails, and a quieter local feel west of downtown.
Chicken-fried steak is a Southern Plains staple: tenderized beef breaded and fried, then covered in peppered gravy. It is a longtime comfort-food favorite in Oklahoma.
Oklahoma onion burgers were born during the Depression: a thin beef patty smashed with lots of sliced onions so they caramelize into the meat. El Reno made the style famous.
Smoked brisket is central to Oklahoma barbecue, often seasoned simply and cooked low and slow over wood. Locals prize the bark, smoke ring, and beefy flavor.
Refined ranch-to-table restaurant highlighting Oklahoma ingredients, bison, and regional cooking in an upscale but welcoming setting.
Beloved breakfast and lunch diner serving biscuits and gravy, chicken-fried steak, and other hearty comfort-food standards in a casual space.
Historic, no-frills burger stand famed for the classic Oklahoma onion burger. Casual and deeply local, with a long-standing reputation.
Moderate for U.S. city breaks: hotels are often cheaper than larger metros, dining is reasonable, and parking is common, though car travel usually adds to visitor costs.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or card prompts; small tips are appreciated.
Find answers to the most common questions about traveling from San Antonio, TX to Oklahoma City, OK by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Oklahoma City, OK, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Oklahoma City, OK buses use the San Antonio, N St Mary's St (Greyhound) to Oklahoma City, E Reno Ave (Greyhound Bus Station) station pair. Use this guide to compare San Antonio, TX and Oklahoma City, OK bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need