Travel Information
Compare bus, train, and flight for Saint-Louis to Milan
Omio recommends booking the train as it is the most popular option from Saint-Louis to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a train which can get you there in 3h 57m. The ticket price range depends on the travel mode: a bus costs an average of $35, and a flight costs an average of $101.
Distance: 165 miles (267 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$45 Average price Cheapest | $261 Average price | $287 Average price |
5h 23m Average total duration 4h 53m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 3h 57m Onboard + 30m Additional time* | 9h 28m Average total duration 6h 28m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Saint-Louis to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 07:10AM | Arrival Time 01:10PM | Duration 6h00 | Departure days Mon | Cheapest price $50 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 04:50PM | Duration 9h05 | Departure days Mon | Cheapest price $52 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 10:00PM | Duration 8h30 | Departure days Mon | Cheapest price $49 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 02:15AM | Duration 7h35 | Departure days Mon | Cheapest price $49 |
Compare prices and tickets Saint-Louis to Milan by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 29
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Apr 04
Why should you book Saint-Louis to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Saint-Louis to Milan.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Saint-Louis to Milan.
Journey information
Overview: Bus from Saint-Louis to Milan
Buses from Saint-Louis to Milan run on average 7 times per day, taking around 4h 53m. Cheap bus tickets for this journey start at $35 (€29) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:45. The fastest bus covers the 165 miles (267 km) distance in 6h 0m.
Distance 165 miles (267 km) |
Average bus duration 4h 53m |
Cheapest ticket price $35 (€29) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 6h 0m |
First bus 00:10 |
Last bus 23:45 |
Bus providers: BlaBlaCar, FlixBus from Saint-Louis to MilanYou can travel by bus between Saint-Louis to Milan with BlaBlaCar, FlixBus for as low as $35 (€29). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Saint-Louis to Milan
Find answers to the most common questions about traveling from Saint-Louis to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Saint-Louis to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Saint-Louis
More options for your journey from Saint-Louis to Milan
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