- Must visit
Science and Industry Museum
Major museum exploring Manchester’s role in science, technology and industry, with historic machinery and railway heritage on the oldest surviving passenger railway station site.
Cheapest price
$64
Average price
$64
Fastest journey
13 h 10 m
Average duration
13 h 10 m
Buses per day
1
Distance
437 km
The best way to find a cheap bus ticket from Penzance to Manchester is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Penzance to Manchester will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $64.
Of the 1 buses that leave Penzance for Manchester on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 437 km distance in an average of 13 h 10 m but if you time it right, some buses will get you there in just 13 h 10 m .
On Sun, Jun 21 the slowest buses will take 13 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Penzance to Manchester among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a flight which can get you there in 1h 10m. The ticket price range depends on the travel mode: a bus costs an average of $26, and a flight costs an average of $105.
Distance: 271 miles (437 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$48 Average price Cheapest | $182 Average price | $193 Average price | $125 Average price (fuel + tolls) |
14h 15m Average total duration 13h 45m Onboard + 30m Additional time* | 7h 49m Average total duration 7h 19m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Penzance to Manchester:
A bus is $134 (€109) less than a train for this route with tickets for a train from Penzance to Manchester costing on average $182 (€149).
A bus is $144 (€118) less than a flight for this route with tickets for a flight from Penzance to Manchester costing on average $193 (€158).
Other travel options to Manchester take longer:
Train takes on average 7h 19m.
Bus takes on average 13h 45m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 08:25AM | Arrival Time 09:10PM | Duration 12h45 | Departure days Tue, Wed, Sat | Cheapest price $45 |
Operator National Express | Departure Time 08:35AM | Arrival Time 09:40PM | Duration 13h05 | Departure days Thu | Cheapest price $35 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 06:10AM | Duration 17h20 | Departure days Tue, Wed | Cheapest price $37 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 11:05AM | Duration 14h40 | Departure days Mon, Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 11:50AM | Duration 14h25 | Departure days Tue, Wed, Thu, Fri | Cheapest price $33 |
Operator National Express | Departure Time 10:05PM | Arrival Time 11:15AM | Duration 13h10 | Departure days Tue, Wed, Sat, Sun | Cheapest price $44 |
The table below shows live departures for Penzance to Manchester buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
NX504 · NX104 · NX120 | On time 8:25 AM Penzance | 12h45 | 9:10 PM Manchester, Coach Station | 2 transfers | |
NX106 · NX120 | On time 10:05 PM Penzance | 13h10 | 11:15 AM Manchester, Coach Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Penzance to Manchester run on average 7 times per day, taking around 13h 45m. Cheap bus tickets for this journey start at $26 (€21) if you book in advance.
The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 271 miles (437 km) distance in 13h 5m.
Distance 271 miles (437 km) |
Average bus duration 13h 45m |
Cheapest ticket price $26 (€21) |
Buses per day 7 |
Fastest bus 13h 5m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 56 days |
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Major museum exploring Manchester’s role in science, technology and industry, with historic machinery and railway heritage on the oldest surviving passenger railway station site.
University museum with acclaimed natural history, archaeology and cultural collections, recently refreshed and especially popular for its dinosaur and ancient Egypt displays.
Central city gallery with fine art, design and decorative arts collections, plus changing exhibitions in a landmark civic building.
Manchester’s best-known creative district, packed with street art, independent shops and photogenic corners that are highly popular online.
Canalside heritage area with Roman roots, warehouses, waterside walks and one of the city’s most atmospheric urban landscapes.
Historic civic square framed by major Victorian architecture and often used for events, making it a classic city-centre stop.
A classic Manchester dessert with shortcrust pastry, raspberry jam, custard, coconut, and a cherry. It is one of the city’s best-known traditional sweet dishes.
A flaky pastry filled with currants, sugar, and butter, originating from Eccles in Greater Manchester. It is a famous regional bake often eaten with tea.
A traditional blood sausage strongly associated with nearby Bury and widely eaten in Manchester, especially as part of a full breakfast.
A stylish and widely loved restaurant inspired by Bombay cafés, known for rich curries, grilled dishes, and a distinctive heritage interior.
A popular casual venue pairing Indian street food with craft beer. It is lively, well-known, and especially good for vegetarian diners.
A celebrated fine-dining restaurant in Manchester known for modern British cooking, polished service, and an elegant setting inside The Midland hotel.
Moderate by UK standards. Budget eats are easy to find, but central hotels and nightlife can be pricey.
Service is often included in restaurants. If not, tip 10-12.5% for good service. Round up in taxis. Tipping is not expected for counter service, but small tips are appreciated.
Official public transport app
Manchester Airport, Manchester -> Manchester Piccadilly, Manchester
Find answers to the most common questions about traveling from Penzance to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

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