- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Omio recommends booking the bus as it is the most popular option from Payerne to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $27 For those with little time, consider booking a bus, which has an average total journey time of 2h 35m. Average ticket prices depend on the travel mode: a bus costs an average of $27, while a flight costs an average of $121.
Distance: 142 miles (230 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$27 Average price Cheapest | $102 Average price | $121 Average price | $80 Average price (fuel + tolls) |
2h 35m Average total duration Fastest 2h 5m Onboard + 30m Additional time* | 5h 35m Average total duration 5h 5m Onboard + 30m Additional time* | 8h 41m Average total duration 6h 41m Onboard + 2h 0m Additional time* | 4h 36m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Payerne to Milan:
A bus is $75 (€61) less than a train for this route with tickets for a train from Payerne to Milan costing on average $102 (€82).
A bus is $95 (€77) less than a flight for this route with tickets for a flight from Payerne to Milan costing on average $121 (€98).
Other travel options to Milan take longer:
Train takes on average 5h 5m.
Flight takes on average 6h 41m.
You'll arrive about 2h 31m sooner (2h 5m by bus vs 4h 36m by car) and save roughly $53 (€43) compared to fuel and tolls ($27 (€22) vs $80 (€65)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Gruppo Di Maio | Departure Time 02:40PM | Arrival Time 05:45AM | Duration 15h05 | Departure days Mon, Fri | Cheapest price $51 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Payerne to Milan run on average 4 times per day, taking around 2h 5m. Cheap bus tickets for this journey start at $25 (€20) if you book in advance.
There are 3 buses per day. The earliest bus runs at 07:30, the last at 23:45. The fastest bus covers the 142 miles (230 km) distance in 2h 5m.
Distance 142 miles (230 km) |
Average bus duration 2h 5m |
Cheapest ticket price $25 (€20) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 2h 5m |
First bus 7:30 AM |
Last bus 11:45 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Payerne to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Payerne to Milan buses use the Châtillon to Milano station pair, with some services arriving at Milano, Autostazione Lampugnano. Use this guide to compare Payerne and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple fast food and dining options available.
Free Wi-Fi available for 30 minutes. ATMs are aTMs available in the main hall.
Ticket office support is available at Milano.
Available at Milano: Parking, Taxis, WC.
Accessibility facilities are available at Milano: Wheelchair accessible facilities available.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
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