- Must visit
Pinacoteca di Brera
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
Omio recommends booking the bus as it is the most popular option from Payerne to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a bus which can get you there in 4h 10m. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $131.
Distance: 142 miles (230 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$51 Average price Cheapest | $208 Average price | $95 Average price | $80 Average price (fuel + tolls) |
4h 40m Average total duration Fastest 4h 10m Onboard + 30m Additional time* | 10h 35m Average total duration 7h 35m Onboard + 3h 0m Additional time* | 4h 51m Average total duration 4h 21m Onboard + 30m Additional time* | 4h 36m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Payerne to Milan:
A bus is $44 (€36) less than a train for this route with tickets for a train from Payerne to Milan costing on average $95 (€77).
A bus is $157 (€126) less than a flight for this route with tickets for a flight from Payerne to Milan costing on average $208 (€167).
Other travel options to Milan take longer:
Train takes on average 4h 21m.
Flight takes on average 7h 35m.
You'll arrive about 26m sooner (4h 10m by bus vs 4h 36m by car) and save roughly $29 (€23) compared to fuel and tolls ($51 (€41) vs $80 (€64)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by BlaBlaCar.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Gruppo Di Maio | Departure Time 02:40PM | Arrival Time 05:45AM | Duration 15h05 | Departure days Mon, Fri | Cheapest price $51 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Payerne to Milan run on average 3 times per day, taking around 4h 10m. Cheap bus tickets for this journey start at $51 (€41) if you book in advance.
There are 2 buses per day. The earliest bus runs at 07:30, the last at 23:45. The fastest bus covers the 142 miles (230 km) distance in 15h 5m.
Distance 142 miles (230 km) |
Average bus duration 4h 10m |
Cheapest ticket price $51 (€41) |
Buses per day 3 |
Direct buses 2 |
Fastest bus 15h 5m |
First bus 7:30 AM |
Last bus 11:45 PM |
High Season Jul - Sep |
Low Season Apr - Jun |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
A major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist holdings and striking city views.
A contemporary museum focused on world cultures and major temporary exhibitions, popular for its modern architecture and changing shows.
Milan’s canal district, best known for waterside walks, photogenic bridges, and lively atmosphere day and night.
A charming historic neighborhood of narrow streets, galleries, boutiques, and classic Milan character, ideal for wandering.
Milan’s main square and the symbolic heart of the city, surrounded by major landmarks and constant urban energy.
Creamy saffron risotto, one of Milan's signature dishes, prized for its rich flavor and golden color.
Braised veal shank cooked slowly until tender, traditionally served with gremolata and often paired with risotto.
Breaded veal cutlet fried in butter, a classic Milanese specialty and one of the city's most famous dishes.
Celebrated fine dining restaurant offering creative haute cuisine with an elegant, Michelin-starred reputation.
Famous central bakery known for panzerotti, a beloved casual stop near the Duomo with constant local appeal.
Modern Milanese restaurant known for refined Lombard classics in a stylish contemporary setting.
Milan is pricier than most Italian cities, especially for hotels, central dining, and aperitivo areas.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Milan Linate Airport, Milan -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Payerne to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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