- Must visit
Edison and Ford Winter Estates Museum
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
The best way to find a cheap bus ticket from Palm Coast, FL to Fort Myers, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palm Coast, FL to Fort Myers, FL will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $52.
On Thu, Nov 05, we found 1 buses from Palm Coast, FL to Fort Myers, FL, including 1 direct services.
On Thu, Nov 05 the direct buses cover the 335 km distance in an average of 11 h but if you time it right, some buses will get you there in just 11 h .
On Thu, Nov 05 the slowest buses will take 11 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Palm Coast, FL to Fort Myers, FL run on average 1 times per day, taking around 6h 45m. Cheap bus tickets for this journey start at $87 if you book in advance.
The earliest bus runs at 07:00, the last at 23:20. The fastest bus covers the 208 miles (335 km) distance in 6h 45m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Palm Coast, FL to Fort Myers, FL.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:20AM | Arrival Time 02:20PM | Duration 11h00 | Departure days Mon, Tue | Cheapest price $55 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 03:20PM | Duration 11h00 | Departure days Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 02:05PM | Arrival Time 10:20PM | Duration 8h15 | Departure days Fri | Cheapest price $98 |
Operator Amtrak | Departure Time 02:55PM | Arrival Time 11:15PM | Duration 8h20 | Departure days Fri | Cheapest price $105 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 03:20PM | Duration 20h30 | Departure days Tue | Cheapest price $107 |
The table below shows live departures for Palm Coast, FL to Fort Myers, FL buses for tomorrow, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:20 AM Palm Coast, FL | 11h00 | 3:20 PM Fort Myers, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Palm Coast, FL to Fort Myers, FL with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Fort Myers, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers, FL trip today.
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
Excellent regional history museum covering Southwest Florida's people, places, and development through engaging permanent exhibitions.
Interactive science museum with aquariums, live animals, and hands-on exhibits that make it especially strong for families and curious adults.
Walkable historic downtown filled with shops, galleries, event spaces, and river views, making it the city's main strolling district.
Large urban nature preserve with boardwalks, trails, and birding, offering a wild contrast to the built-up city center.
Palm-lined downtown street known for preserved architecture, boutiques, murals, and an easy introduction to the city's historic core.
Fresh Gulf shrimp, often peeled and eaten chilled or quickly sautéed. A Southwest Florida staple thanks to nearby shrimping waters and seafood culture.
A Florida classic of flaky local fish, usually grouper, served blackened, grilled, or fried in a sandwich. Popular along Fort Myers waterfronts.
Cracked Florida stone crab claws served chilled with mustard sauce. A prized seasonal seafood known across coastal South Florida and the Gulf.
Established fine dining restaurant serving refined seafood and steaks in an elegant historic downtown setting.
Casual waterfront seafood spot known for fresh local shrimp, grouper, and island atmosphere near the marina.
Beloved local Cuban cafe offering pressed sandwiches, coffee, pastries, and traditional Latin comfort food in a casual setting.
Moderate for Florida beach travel. Hotels and dining run mid-range, while car travel and parking add costs. Cheaper than Miami, but pricier than many inland US cities.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes and bars.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Fort Myers, FL.
Find answers to the most common questions about traveling from Palm Coast, FL to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

Most Palm Coast, FL to Fort Myers, FL buses use the Palm Coast, E Highway 100 (Shell Gas Station) to Fort Myers, Rosa Parks Transit Center station pair. Use this guide to compare Palm Coast, FL and Fort Myers, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Palm Coast, E Highway 100 (Shell Gas Station) is 12 km from Palm Coast city centre. Public transport options include:
Palm Coast, E Highway 100 (Shell Gas Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Palm Coast, E Highway 100 (Shell Gas Station). ATMs are available at Palm Coast, E Highway 100 (Shell Gas Station).
Ticket office support is available at Palm Coast, E Highway 100 (Shell Gas Station).
Available at Palm Coast, E Highway 100 (Shell Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Palm Coast, E Highway 100 (Shell Gas Station): Basic accessibility available.
Fort Myers, Rosa Parks Transit Center is 3 km from Fort Myers city centre. Public transport options include:
Fort Myers, Rosa Parks Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Fort Myers, Rosa Parks Transit Center. ATMs are available at Fort Myers, Rosa Parks Transit Center.
Ticket office support is available at Fort Myers, Rosa Parks Transit Center.
Available at Fort Myers, Rosa Parks Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Fort Myers, Rosa Parks Transit Center: Wheelchair accessible routes provided.
Check bus stations information for Palm Coast, FL and Fort Myers, FL, including where buses depart and arrive on this route.