Travel Information
Compare bus for Orlando, FL to Key Largo, FL
Omio recommends booking the bus as it is the most popular option from Orlando, FL to Key Largo, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $73 For those with little time, consider booking a bus, which has an average total journey time of 6h 55m. Average ticket prices depend on the travel mode: a bus costs an average of $73, while a bus costs an average of $73.
Distance: 245 miles (395 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$73 Average price Cheapest | $56 Average price (fuel + tolls) |
6h 55m Average total duration Fastest 6h 25m Onboard + 30m Additional time* | 4h 40m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Key Largo, FL:
A bus is $201 less than a flight for this route with tickets for a flight from Orlando, FL to Key Largo, FL costing on average $274.
Other travel options to Key Largo, FL take longer:
Bus takes on average 6h 25m.
Tickets start at around $73 compared to roughly $56 in fuel and tolls — a saving of about $-16.31. The journey takes 6h 25m versus 4h 40m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Orlando, FL to Key Largo, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 09:20AM | Duration 8h35 | Departure days Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 09:20AM | Duration 8h05 | Departure days Sun | Cheapest price $41 |
Operator Greyhound | Departure Time 03:05AM | Arrival Time 10:30AM | Duration 7h25 | Departure days Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 04:30PM | Duration 11h15 | Departure days Thu | Cheapest price $88 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 12:20PM | Duration 7h00 | Departure days Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 12:20PM | Duration 6h30 | Departure days Sun | Cheapest price $34 |
Operator Jet Set Express | Departure Time 07:00AM | Arrival Time 06:30AM | Duration 23h30 | Departure days Tue, Wed | Cheapest price $64 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 06:25AM | Duration 7h20 | Departure days Sun | Cheapest price $34 |
Compare prices and tickets Orlando, FL to Key Largo, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
Journey information
Overview: Bus from Orlando, FL to Key Largo, FL
Buses from Orlando, FL to Key Largo, FL run on average 5 times per day, taking around 6h 25m. Cheap bus tickets for this journey start at $38 if you book in advance.
The earliest bus runs at 12:40, the last at 19:40. The fastest bus covers the 245 miles (395 km) distance in 5h 35m.
Distance 245 miles (395 km) |
Average bus duration 6h 25m |
Cheapest ticket price $38 |
Buses per day 5 |
Fastest bus 5h 35m |
First bus 12:40 PM |
Last bus 7:40 PM |
Cheapest Month Jul |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Oct - Dec |
Bus providers: FlixBus, Greyhound from Orlando, FL to Key Largo, FLYou can travel by bus between Orlando, FL to Key Largo, FL with FlixBus, Greyhound for as low as $38. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Key Largo, FL
Find answers to the most common questions about traveling from Orlando, FL to Key Largo, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key Largo, FL, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Orlando, FL to Key Largo, FL
Most Orlando, FL to Key Largo, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Key Largo, Overseas Hwy (Burger King) station pair. Use this guide to compare Orlando, FL and Key Largo, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Orlando, FL station do buses to Key Largo, FL leave from?
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Getting to Orlando, The Florida Mall from Orlando city centre
Which Key Largo, FL station do buses from Orlando, FL arrive at?
Getting to Key Largo, Overseas Hwy (Burger King) from Key Largo city centre
Key Largo, Overseas Hwy (Burger King) is 1 km from Key Largo city centre. Public transport options include:
Key Largo, Overseas Hwy (Burger King) bus station facilities and services
Key Largo, Overseas Hwy (Burger King) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Located near Burger King.
Wi-Fi and ATMs
Wi-Fi is available at Key Largo, Overseas Hwy (Burger King). ATMs are available at Key Largo, Overseas Hwy (Burger King).
Tickets and information
Ticket office support is available at Key Largo, Overseas Hwy (Burger King).
Parking, taxis and toilets
Available at Key Largo, Overseas Hwy (Burger King): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Key Largo, Overseas Hwy (Burger King): Basic accessibility available.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Key Largo, FL
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