- Must visit
Science and Industry Museum
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Cheapest price
$29
Average price
$36
Fastest journey
2 h 55 m
Average duration
3 h
Buses per day
19
Distance
189 km
The best way to find a cheap bus ticket from Milton Keynes to Manchester is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milton Keynes to Manchester will cost around $36 if you buy it on the day, but the cheapest tickets can be found for only $29.
Of the 19 buses that leave Milton Keynes for Manchester on Wed, Aug 05, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 189 km distance in an average of 3 h but if you time it right, some buses will get you there in just 2 h 55 m .
On Wed, Aug 05 the slowest buses will take 3 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
NX541
NX540
NX541
NX422
NX540
NX540
NX540
NX540
NX540
NX540Buses from Milton Keynes to Manchester run on average 8 times per day, taking around 3h 0m. Cheap bus tickets for this journey start at $17 (€13) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 117 miles (189 km) distance in 2h 40m.
Distance 117 miles (189 km) |
Average bus duration 3h 0m |
Cheapest ticket price $17 (€13) |
Buses per day 8 |
Direct buses 6 |
Fastest bus 2h 40m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 14 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 12:50AM | Arrival Time 06:15AM | Duration 5h25 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 03:35AM | Arrival Time 07:35AM | Duration 4h00 | Departure days Wed | Cheapest price $37 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 11:40AM | Duration 4h50 | Departure days Sat, Sun | Cheapest price $59 |
Operator National Express | Departure Time 09:05AM | Arrival Time 12:10PM | Duration 3h05 | Departure days Wed | Cheapest price $33 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 04:10PM | Duration 5h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator National Express | Departure Time 10:40AM | Arrival Time 03:00PM | Duration 4h20 | Departure days Wed | Cheapest price $45 |
Operator National Express | Departure Time 10:45AM | Arrival Time 01:50PM | Duration 3h05 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 11:40AM | Arrival Time 02:40PM | Duration 3h00 | Departure days Wed | Cheapest price $29 |
Operator National Express | Departure Time 12:10PM | Arrival Time 04:05PM | Duration 3h55 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 01:25PM | Arrival Time 04:30PM | Duration 3h05 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 03:15PM | Arrival Time 07:30PM | Duration 4h15 | Departure days Wed | Cheapest price $37 |
Operator National Express | Departure Time 04:30PM | Arrival Time 07:30PM | Duration 3h00 | Departure days Wed | Cheapest price $37 |
Operator National Express | Departure Time 05:00PM | Arrival Time 08:50PM | Duration 3h50 | Departure days Wed | Cheapest price $35 |
Operator National Express | Departure Time 05:45PM | Arrival Time 09:35PM | Duration 3h50 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 07:10PM | Arrival Time 10:10PM | Duration 3h00 | Departure days Wed | Cheapest price $35 |
Operator National Express | Departure Time 07:25PM | Arrival Time 11:15PM | Duration 3h50 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 08:50PM | Arrival Time 12:25AM | Duration 3h35 | Departure days Wed | Cheapest price $37 |
Operator National Express | Departure Time 09:35PM | Arrival Time 12:30AM | Duration 2h55 | Departure days Wed | Cheapest price $33 |
Operator National Express | Departure Time 10:05PM | Arrival Time 01:40AM | Duration 3h35 | Departure days Wed | Cheapest price $29 |
Operator National Express | Departure Time 10:35PM | Arrival Time 06:05AM | Duration 7h30 | Departure days Wed | Cheapest price $53 |
The table below shows live departures for Milton Keynes to Manchester buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 10:40 AM Milton Keynes, Central Railway Station | 5h30 | 4:10 PM Manchester, Shudehill Interchange | 1 transfer | |
FlixBus · FlixBus | 10:40 AM Milton Keynes, Central Railway Station | 5h05 | 3:45 PM Manchester, Princess Road / Moss Lane East | 1 transfer | |
| Wednesday, August 5 | |||||
NX422 | 12:50 AM Milton Keynes, Coachway | 5h25 | 6:15 AM Manchester, Coach Station | 0 transfersDirect | |
NX422 · NX424 | 12:50 AM Milton Keynes, Coachway | 5h15 | 6:05 AM Manchester, Coach Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Major art museum with Pre-Raphaelite works, design, and changing exhibitions. A central cultural stop with broad appeal.
The University of Manchester museum spans dinosaurs, Egypt, nature, and anthropology. Recently renewed and excellent for varied interests.
Historic canal-side district with Roman remains, warehouses, and walkable towpaths. One of Manchester's most atmospheric urban areas.
Central square framed by grand civic buildings, museums, and monuments. A classic starting point for exploring the city centre.
Creative quarter of street art, music history, indie shops, and nightlife. It is one of Manchester's most characterful neighborhoods.
A flaky pastry pie filled with spiced potatoes, onion and often chickpeas. Created by Manchester’s South Asian community and now a city staple.
A comforting Northern pudding of suet pastry filled with beef and onion, traditionally steamed and served with gravy. Common in Greater Manchester pubs.
Manchester’s classic order of battered fish with chips, often served with mushy peas and curry sauce. A long-standing local takeaway favourite.
Iconic market bakery and café known for Manchester tarts, Eccles cakes and hearty lunches. Casual, busy and deeply rooted in local food culture.
Refined modern British fine dining in a restored townhouse. Known for tasting menus, polished service and one of Manchester’s top culinary reputations.
Lively Indian restaurant famous for bold curries, grills and chaat. A long-established Rusholme favourite with a casual, energetic atmosphere.
Moderate for the UK: hotels often cost less than London, while dining and transit are manageable for tourists with many mid-range options.
Service may be included. If not, 10-12.5% in restaurants is common for good service. Round up or add a little for taxis. Cafe tipping is optional.
Find answers to the most common questions about traveling from Milton Keynes to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

Most Milton Keynes to Manchester buses use the Milton Keynes, Coachway to Manchester, Coach Station station pair, with some services arriving at Manchester, Shudehill Interchange. Use this guide to compare Milton Keynes and Manchester bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Manchester, Coach Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café at the Station (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located within the station for cash withdrawals.
Ticket office support is available at Manchester, Coach Station.
Available at Manchester, Coach Station: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Coach Station: Ramps, assistance.
Manchester, Shudehill Interchange has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Manchester, Shudehill Interchange.
Available at Manchester, Shudehill Interchange: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Shudehill Interchange: Elevators, ramps.
Here are some other resources that might have the information you need