- Must visit
Everson Museum Of Art
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
Omio recommends booking the bus as it is the most popular option from Lexington, KY to Syracuse, NY among Omio's users. If you are prioritising price take the bus with prices starting from $240. For those with little time consider booking a flight which can get you there in 6h 23m. The ticket price range depends on the travel mode: a bus costs an average of $240, and a flight costs an average of $406.
Distance: 559 miles (901 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$240 Average price Cheapest | $450 Average price | $17 Average price (fuel + tolls) |
19h 0m Average total duration 18h 30m Onboard + 30m Additional time* | 9h 23m Average total duration Fastest 6h 23m Onboard + 3h 0m Additional time* | 9h 57m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lexington, KY to Syracuse, NY:
A bus is $210 (€172) less than a flight for this route with tickets for a flight from Lexington, KY to Syracuse, NY costing on average $450 (€368).
Other travel options to Syracuse, NY take longer:
Bus takes on average 18h 30m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:55AM | Arrival Time 08:25PM | Duration 18h30 | Departure days Wed, Thu, Sat | Cheapest price $105 |
Operator Greyhound | Departure Time 05:55AM | Arrival Time 12:25AM | Duration 18h30 | Departure days Fri | Cheapest price $240 |
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lexington, KY to Syracuse, NY run on average 1 times per day, taking around 18h 30m. Cheap bus tickets for this journey start at $240 (€196) if you book in advance.
The earliest bus runs at 01:55, the last at 21:00. The fastest bus covers the 559 miles (901 km) distance in 18h 30m.
Distance 559 miles (901 km) |
Average bus duration 18h 30m |
Cheapest ticket price $240 (€196) |
Buses per day 1 |
Fastest bus 18h 30m |
First bus 1:55 AM |
Last bus 9:00 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 4 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
A local history museum in the last remaining weighlock building in the United States, focusing on the Erie Canal’s impact on Syracuse and New York State.
A hands-on science museum in downtown Syracuse with interactive exhibits and a planetarium, popular with families and visitors interested in STEM.
Syracuse’s best-known historic district, filled with restored warehouses, lively streets, and a strong mix of shopping, architecture, and nightlife.
A popular waterfront recreation area with trails, lake views, and sunset spots that are frequently featured in local social media posts.
A central downtown square known for historic buildings, events, and seasonal programming, including its popular winter ice rink.
Small potatoes boiled in very salty water until the skins wrinkle, then served with melted butter. They are a signature Central New York dish with roots in the region's salt industry.
A spicy pasta dish with chicken, rigatoni, peppers, and a creamy tomato sauce. Though more closely tied to nearby Utica, it is widely loved across Central New York and commonly found in Syracuse.
A bakery-style rectangular pizza served at room temperature with thick crust, tomato sauce, and little or no cheese. It is a classic Upstate New York snack and party food.
A long-running Syracuse favorite known for handmade pasta, spicy hot tomato oil, and a lively downtown atmosphere.
An established Italian restaurant on the north side, appreciated for classic pasta dishes, warm service, and a cozy neighborhood feel.
A famous casual barbecue restaurant and roadhouse-style venue known for smoked meats, classic sides, and a bustling, iconic setting.
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and fine dining cost more during peak dates.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Lexington, KY to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need