- Recommended
History Center of San Luis Obispo County
Regional history museum in a restored Carnegie Library with exhibits on Indigenous communities, ranching, rail, and town life.
Omio recommends booking the train as it is the most popular option from Laguna Niguel, CA to San Luis Obispo, CA among Omio's users.
Distance: 207 miles (334 km)
| Bus | Most popular Train | Driving |
|---|---|---|
€40 Average price (fuel + tolls) | ||
4h 10m Average total duration (door-to-door) | ||
Direct Options | Direct Options | Direct Options |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator OCTA | Departure Time 06:05PM | Arrival Time 01:25PM | Duration 19h20 | Departure days Tue, Fri | Cheapest price €41 |
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Laguna Niguel, CA to San Luis Obispo, CA and enjoy the approximately 207 miles (334 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 03:45, the last at 19:00.
Distance 207 miles (334 km) |
First bus 3:45 AM |
Last bus 7:00 PM |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of San Luis Obispo, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Luis Obispo, CA trip today.
Regional history museum in a restored Carnegie Library with exhibits on Indigenous communities, ranching, rail, and town life.
Rail museum by the station with model layouts, restored equipment, and hands-on displays for families and train enthusiasts.
Children’s museum downtown with interactive science, art, and play exhibits designed for younger visitors and family outings.
Downtown creekside park with lawns, paths, public art, and regular community events in the center of the city.
Popular local peak with a short but steep trail, broad city views, and sunset scenery close to downtown.
Compact downtown district with shops, historic facades, galleries, and walkable streets linking major sights and events.
Find answers to the most common questions about traveling from Laguna Niguel, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

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