- Must visit
Science and Industry Museum
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Omio recommends booking the train as it is the most popular option from Holyhead to Manchester among Omio's users. If you are prioritising price, take the train, with an average ticket price of $57 For those with little time, consider booking a train, which has an average total journey time of 3h 16m. Average ticket prices depend on the travel mode: a train costs an average of $57, while a train costs an average of $57.
Distance: 99 miles (160 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$57 Average price Cheapest | $45 Average price (fuel + tolls) | |
3h 16m Average total duration Fastest 2h 46m Onboard + 30m Additional time* | 2h 23m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Holyhead to Manchester and enjoy the approximately 99 miles (160 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:56, the last at 23:45.
Distance 99 miles (160 km) |
First bus 2:56 AM |
Last bus 11:45 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Thu |
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Major art museum with Pre-Raphaelite works, design, and changing exhibitions. A central cultural stop with broad appeal.
The University of Manchester museum spans dinosaurs, Egypt, nature, and anthropology. Recently renewed and excellent for varied interests.
Historic canal-side district with Roman remains, warehouses, and walkable towpaths. One of Manchester's most atmospheric urban areas.
Central square framed by grand civic buildings, museums, and monuments. A classic starting point for exploring the city centre.
Creative quarter of street art, music history, indie shops, and nightlife. It is one of Manchester's most characterful neighborhoods.
A flaky pastry pie filled with spiced potatoes, onion and often chickpeas. Created by Manchester’s South Asian community and now a city staple.
A comforting Northern pudding of suet pastry filled with beef and onion, traditionally steamed and served with gravy. Common in Greater Manchester pubs.
Manchester’s classic order of battered fish with chips, often served with mushy peas and curry sauce. A long-standing local takeaway favourite.
Iconic market bakery and café known for Manchester tarts, Eccles cakes and hearty lunches. Casual, busy and deeply rooted in local food culture.
Refined modern British fine dining in a restored townhouse. Known for tasting menus, polished service and one of Manchester’s top culinary reputations.
Lively Indian restaurant famous for bold curries, grills and chaat. A long-established Rusholme favourite with a casual, energetic atmosphere.
Moderate for the UK: hotels often cost less than London, while dining and transit are manageable for tourists with many mid-range options.
Service may be included. If not, 10-12.5% in restaurants is common for good service. Round up or add a little for taxis. Cafe tipping is optional.
Find answers to the most common questions about traveling from Holyhead to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

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