- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Omio recommends booking the flight as it is the most popular option from Greenville, NC to Detroit, MI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $143 For those with little time, consider booking a flight, which has an average total journey time of 6h 25m. Average ticket prices depend on the travel mode: a bus costs an average of $143, while a flight costs an average of $793.
Distance: 554 miles (893 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$143 Average price Cheapest | $793 Average price | $152 Average price (fuel + tolls) |
24h 38m Average total duration 24h 8m Onboard + 30m Additional time* | 6h 25m Average total duration Fastest 4h 25m Onboard + 2h 0m Additional time* | 12h 2m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, NC to Detroit, MI:
A bus is $651 less than a flight for this route with tickets for a flight from Greenville, NC to Detroit, MI costing on average $793.
Other travel options to Detroit, MI take longer:
Bus takes on average 24h 8m.
Tickets start at around $143 compared to roughly $152 in fuel and tolls — a saving of about $9. The journey takes 24h 8m versus 12h 2m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:20PM | Arrival Time 09:45PM | Duration 30h25 | Departure days Mon, Wed | Cheapest price $197 |
Operator Greyhound USA | Departure Time 06:20PM | Arrival Time 05:45PM | Duration 47h25 | Departure days Thu, Sun | Cheapest price $199 |
Operator Greyhound | Departure Time 10:45PM | Arrival Time 01:10PM | Duration 38h25 | Departure days Tue | Cheapest price $173 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, NC to Detroit, MI run on average 2 times per day, taking around 24h 8m. Cheap bus tickets for this journey start at $94 if you book in advance.
The earliest bus runs at 00:30, the last at 23:25. The fastest bus covers the 554 miles (893 km) distance in 20h 5m.
Distance 554 miles (893 km) |
Average bus duration 24h 8m |
Cheapest ticket price $94 |
Buses per day 2 |
Fastest bus 20h 5m |
First bus 12:30 AM |
Last bus 11:25 PM |
Cheapest Month Aug |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Find answers to the most common questions about traveling from Greenville, NC to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Greenville, NC to Detroit, MI buses use the Greenville, S Pitt St (Butterfield Transportation Center) to Detroit, Greyhound Terminal station pair. Use this guide to compare Greenville, NC and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Here are some other resources that might have the information you need