- Must visit
Reynolda House Museum of American Art
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
The best way to find a cheap bus ticket from Charleston, WV to Winston Salem, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, WV to Winston Salem, NC will cost around $78 if you buy it on the day, but the cheapest tickets can be found for only $78.
On Sat, Oct 31, we found 1 buses from Charleston, WV to Winston Salem, NC, including 1 direct services.
On Sat, Oct 31 the direct buses cover the 279 km distance in an average of 4 h 55 m but if you time it right, some buses will get you there in just 4 h 55 m .
On Sat, Oct 31 the slowest buses will take 4 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Charleston, WV to Winston Salem, NC run on average 1 times per day, taking around 4h 55m. Cheap bus tickets for this journey start at $53 (€44) if you book in advance.
There are 1 buses per day. The earliest bus runs at 05:15, the last at 05:20. The fastest bus covers the 173 miles (279 km) distance in 4h 55m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Charleston, WV to Winston Salem, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 05:20AM | Arrival Time 10:15AM | Duration 4h55 | Departure days Mon, Fri, Sun | Cheapest price $54 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 02:15PM | Duration 4h55 | Departure days Tue, Sat | Cheapest price $56 |
Operator Greyhound | Departure Time 10:20AM | Arrival Time 03:15PM | Duration 4h55 | Departure days Wed, Thu | Cheapest price $49 |
The table below shows live departures for Charleston, WV to Winston Salem, NC buses for today, Friday, October 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:20 AM Charleston, WV | 4h55 | 10:15 AM Winston Salem, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Charleston, WV to Winston Salem, NC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Winston Salem, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Winston Salem, NC trip today.
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
Living-history museum area with restored buildings, costumed interpretation, and exhibits on Moravian life in early Salem.
Children's museum with hands-on exhibits on science, careers, and play, designed for curious families and younger visitors.
Walkable historic district with brick sidewalks, restored structures, and museum sites that showcase Winston-Salem's Moravian roots.
Large urban park with trails, gardens, sports facilities, and open lawns popular for everyday recreation and seasonal events.
Downtown arts district known for galleries, murals, shops, and frequent public events in a compact, easy-to-explore area.
Moravian chicken pie is a savory double-crust pie filled with chicken and rich gravy, a long-standing Winston-Salem tradition rooted in the city's Moravian heritage.
Moravian sugar cake is a sweet yeasted coffee cake topped with butter, cinnamon, and brown sugar. It is a signature local baked good tied to Old Salem traditions.
Moravian cookies are very thin, crisp spiced cookies, often ginger or sugar. They are a historic Salem bakery specialty and a classic local souvenir snack.
Historic bakery and cafe in Old Salem known for Moravian sugar cake, cookies, and simple lunches in a traditional setting.
Casual local barbecue spot serving Lexington-style chopped pork, brisket, ribs, and classic North Carolina sides.
Lively downtown restaurant and bar focused on Southern comfort food, fried chicken, biscuits, and regional brunch favorites.
Moderate for U.S. city breaks. Hotels and dining are usually cheaper than major U.S. hubs, while car use often matters more than public transit.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Winston Salem, NC.
Find answers to the most common questions about traveling from Charleston, WV to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.

Most Charleston, WV to Winston Salem, NC buses use the Charleston, Greyhound Bus Station to Winston Salem, W 5th St (Greyhound Bus Station) station pair. Use this guide to compare Charleston, WV and Winston Salem, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charleston, Greyhound Bus Station is 1 km from Charleston city centre. Public transport options include:
Charleston, Greyhound Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi available in the waiting area. ATMs are available at Charleston, Greyhound Bus Station.
Ticket office support is available at Charleston, Greyhound Bus Station.
Available at Charleston, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Greyhound Bus Station: Wheelchair accessible entrances available.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Check bus stations information for Charleston, WV and Winston Salem, NC, including where buses depart and arrive on this route.