The cheapest and fastest buses from Des Moines, IA to Pueblo, CO
Cheapest price
$228
Average price
$228
Fastest journey
1 d 2 h 15 m
Average duration
1 d 2 h 15 m
Buses per day
1
Distance
1008 km
The best way to find a cheap bus ticket from Des Moines, IA to Pueblo, CO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Pueblo, CO will cost around $228 if you buy it on the day, but the cheapest tickets can be found for only $228.
It's difficult to get from Des Moines, IA to Pueblo, CO without transferring at least once.
7:15 PM26h15Des Moines, IA9:30 PMPueblo, CO$2281One-way1 transfer
7:15 PM26h15Des Moines, IA9:30 PMPueblo, CO$2281One-way1 transfer
Travel Information
Compare bus for Des Moines, IA to Pueblo, CO
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Pueblo, CO among Omio's users. If you are prioritising price take the bus with prices starting from $228. For those with little time consider booking a bus which can get you there in 26h 35m. The ticket price range depends on the travel mode: a bus costs an average of $228, and a bus costs an average of $228.
Distance: 626 miles (1008 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$228 Average price Cheapest | $148 Average price (fuel + tolls) |
27h 5m Average total duration Fastest 26h 35m Onboard + 30m Additional time* | 11h 0m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Pueblo, CO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 07:15PM | Arrival Time 09:30PM | Duration 26h15 | Departure days Mon, Wed, Sun | Cheapest price $228 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 04:35PM | Duration 22h00 | Departure days Tue, Thu, Sat | Cheapest price $103 |
Live departures
Des Moines, IA to Pueblo, CO bus times
The table below shows live departures for Des Moines, IA to Pueblo, CO buses for today, Saturday, July 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 7:35 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 22h00 | 4:35 PM Pueblo, Court St / W 2nd St (Pueblo Transit Center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Pueblo, CO by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 19
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Jul 21
Jul 22
Jul 23
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Jul 25
Why should you book Des Moines, IA to Pueblo, CO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Des Moines, IA to Pueblo, CO
Buses from Des Moines, IA to Pueblo, CO run on average 1 times per day, taking around 26h 35m. Cheap bus tickets for this journey start at $228 (€187) if you book in advance.
The earliest bus runs at 05:30, the last at 22:25. The fastest bus covers the 626 miles (1008 km) distance in 26h 15m.
Distance 626 miles (1008 km) |
Average bus duration 26h 35m |
Cheapest ticket price $228 (€187) |
Buses per day 1 |
Fastest bus 26h 15m |
First bus 5:30 AM |
Last bus 10:25 PM |
High Season Jan - Mar |
Low Season Jan - Mar |
Bus providers: Greyhound from Des Moines, IA to Pueblo, COYou can travel by bus between Des Moines, IA to Pueblo, CO with Greyhound for as low as $228 (€187). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Des Moines, IA to Pueblo, CO
Find answers to the most common questions about traveling from Des Moines, IA to Pueblo, CO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pueblo, CO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Pueblo, CO
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