- Must visit
Science and Industry Museum
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Buses from Aylesbury to Manchester run on average 3 times per day, taking around 5h 21m. Cheap bus tickets for this journey start at $28 (€23) if you book in advance.
The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 129 miles (208 km) distance in 3h 55m.
Distance 129 miles (208 km) |
Average bus duration 5h 21m |
Cheapest ticket price $28 (€23) |
Buses per day 3 |
Fastest bus 3h 55m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 14 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Aylesbury to Manchester.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:50AM | Arrival Time 11:50AM | Duration 9h00 | Departure days Mon | Cheapest price $24 |
Operator FlixBus | Departure Time 03:35AM | Arrival Time 10:50AM | Duration 7h15 | Departure days Sat | Cheapest price $19 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 11:10AM | Duration 3h20 | Departure days Thu | Cheapest price $22 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 06:30PM | Duration 8h50 | Departure days Wed | Cheapest price $58 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 04:10PM | Duration 5h30 | Departure days Fri, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 12:35PM | Arrival Time 04:05PM | Duration 3h30 | Departure days Wed | Cheapest price $16 |
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Major art museum with Pre-Raphaelite works, design, and changing exhibitions. A central cultural stop with broad appeal.
The University of Manchester museum spans dinosaurs, Egypt, nature, and anthropology. Recently renewed and excellent for varied interests.
Historic canal-side district with Roman remains, warehouses, and walkable towpaths. One of Manchester's most atmospheric urban areas.
Central square framed by grand civic buildings, museums, and monuments. A classic starting point for exploring the city centre.
Creative quarter of street art, music history, indie shops, and nightlife. It is one of Manchester's most characterful neighborhoods.
A flaky pastry pie filled with spiced potatoes, onion and often chickpeas. Created by Manchester’s South Asian community and now a city staple.
A comforting Northern pudding of suet pastry filled with beef and onion, traditionally steamed and served with gravy. Common in Greater Manchester pubs.
Manchester’s classic order of battered fish with chips, often served with mushy peas and curry sauce. A long-standing local takeaway favourite.
Iconic market bakery and café known for Manchester tarts, Eccles cakes and hearty lunches. Casual, busy and deeply rooted in local food culture.
Refined modern British fine dining in a restored townhouse. Known for tasting menus, polished service and one of Manchester’s top culinary reputations.
Lively Indian restaurant famous for bold curries, grills and chaat. A long-established Rusholme favourite with a casual, energetic atmosphere.
Moderate for the UK: hotels often cost less than London, while dining and transit are manageable for tourists with many mid-range options.
Service may be included. If not, 10-12.5% in restaurants is common for good service. Round up or add a little for taxis. Cafe tipping is optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Manchester.
Find answers to the most common questions about traveling from Aylesbury to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

Most Aylesbury to Manchester buses use the to Manchester, Shudehill Interchange station pair, with some services arriving at Manchester, Princess Road / Moss Lane East. Use this guide to compare Aylesbury and Manchester bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Manchester, Shudehill Interchange has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Manchester, Shudehill Interchange.
Available at Manchester, Shudehill Interchange: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Shudehill Interchange: Elevators, ramps.
Manchester, Princess Road / Moss Lane East is 2 km from Manchester city centre. Public transport options include:
Manchester, Princess Road / Moss Lane East has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Manchester, Princess Road / Moss Lane East. ATMs are available at Manchester, Princess Road / Moss Lane East.
Ticket office support is available at Manchester, Princess Road / Moss Lane East.
Available at Manchester, Princess Road / Moss Lane East: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Princess Road / Moss Lane East: Accessible for wheelchairs.
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