Travel Information
Compare train and bus for Milan to Mendrisio
Omio recommends booking the train as it is the most popular option from Milan to Mendrisio among Omio's users. If you are prioritising price take the train with prices starting from $8. For those with little time consider booking a bus which can get you there in 46m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.0kg. The ticket price range depends on the travel mode: a train costs an average of $8, and a bus costs an average of $6.
Distance: 29 miles (48 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$8 Average price Cheapest | $8 Average price | $83 Average price (fuel + tolls) |
1h 19m Average total duration 49m Onboard + 30m Additional time* | 1h 16m Average total duration Fastest 46m Onboard + 30m Additional time* | 1h 2m Average total duration (door-to-door) |
0.0 - 0.0kg CO2 emissions Lowest | 0.0 - 0.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Mendrisio:
A train is $0.10 (€0.08) less than a bus for this route with tickets for a bus from Milan to Mendrisio costing on average $8 (€7).
Other travel options to Mendrisio take longer:
Train takes on average 49m.
Travel optionsfrom Milan to Mendrisio
How to get from Milan to Mendrisio by train, bus or flight.
Our recommendation
The best way to travel from Milan to Mendrisio is by taking a bus because it’s the best combination of price and speed.
FlixBus5:20 PM1h05Milano, Autostazione Lampugnano6:25 PMComo, Piazzale San Gottardo (Stazione San Giovanni)$71One-way0 transfers
Cheapest
FlixBus5:20 PM1h05Milano, Autostazione Lampugnano6:25 PMComo, Piazzale San Gottardo (Stazione San Giovanni)$71One-way0 transfers
Fastest
Regionale TRENORD 2551611:43 AM0h46Milan Centrale12:29 PMChiasso station$81One-way0 transfers
Other options
Regionale TRENORD 255087:43 AM0h46Milan Centrale8:29 AMChiasso station$81One-way0 transfers
Regionale TRENORD 255222:43 PM0h46Milan Centrale3:29 PMChiasso station$81One-way0 transfers
Regionale TRENORD 255066:43 AM0h46Milan Centrale7:29 AMChiasso station$81One-way0 transfers
FlixBus4:35 PM1h50Assago, Viale Milanofiori (Assago M2)6:25 PMComo, Piazzale San Gottardo (Stazione San Giovanni)$71One-way0 transfers
FlixBus7:00 AM0h50Milano, Autostazione Lampugnano7:50 AMComo, Piazzale San Gottardo (Stazione San Giovanni)$91One-way0 transfers
FlixBus7:25 PM0h50Milano, Autostazione Lampugnano8:15 PMComo, Piazzale San Gottardo (Stazione San Giovanni)$91One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Milan to Mendrisio
Travel to Mendrisio easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Mendrisio.

This is compared to other travel options from Milan to Mendrisio:
A train is $0.10 (€0.08) less than a bus for this route with tickets for a bus from Milan to Mendrisio costing on average $8 (€7).
Other travel options to Mendrisio take longer:
Train takes on average 49m.
- Around 43 trains per day.
- Around 17 buses per day.
However, we recommend checking specific travel dates for your route between Milan and Mendrisio as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Milan Centrale and arrive in Chiasso station.
- Buses mostly depart from Ferno, Aeroporto di Milano-Malpensa T1 and arrive in Como, Piazzale San Gottardo (Stazione San Giovanni).
- Travel with BlaBlaCar, Flibco, FlixBus to go to Mendrisio by bus.
- Travel with Regionale, Trenitalia EuroCity, Swiss Federal Railways (SBB CFF FFS) to go to Mendrisio by train.
- 17 direct buses per day with BlaBlaCar, Flibco, FlixBus.
- 28 direct trains per day with Regionale, Swiss Federal Railways (SBB CFF FFS).
Travelling from Milan to Mendrisio: related information
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