Travel Information
Compare train and bus for Milan to Mendrisio
Omio recommends booking the train as it is the most popular option from Milan to Mendrisio among Omio's users. If you are prioritising price, take the train, with an average ticket price of €6 For those with little time, consider booking a train, which has an average total journey time of 1h 23m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.0kg. Average ticket prices depend on the travel mode: a train costs an average of €6, while a bus costs an average of €12.
Distance: 29 miles (48 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€6 Average price Cheapest | €12 Average price | €68 Average price (fuel + tolls) |
1h 23m Average total duration Fastest 53m Onboard + 30m Additional time* | 1h 40m Average total duration 1h 10m Onboard + 30m Additional time* | 1h 2m Average total duration (door-to-door) |
0.0 - 0.0kg CO2 emissions Lowest | 0.0 - 0.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Mendrisio:
A train is €6 less than a bus for this route with tickets for a bus from Milan to Mendrisio costing on average €12.
Other travel options to Mendrisio take longer:
Bus takes on average 1h 40m.
The journey is about 9m faster (53m by train vs 1h 2m by car) and roughly €62 cheaper once you factor in fuel and tolls (€6 vs €68). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Milan to Mendrisio
How to get from Milan to Mendrisio by train, bus or flight.
Our recommendation
The best way to travel from Milan to Mendrisio is by taking a bus because it’s the best combination of price and speed.
24947:10 AM0h35Milano, Autostazione Lampugnano7:45 AMComo, Via Colombo Cristoforo (Grandate FNM)€51One-way0 transfers
Cheapest
24947:10 AM0h35Milano, Autostazione Lampugnano7:45 AMComo, Via Colombo Cristoforo (Grandate FNM)€51One-way0 transfers
Fastest
24947:10 AM0h35Milano, Autostazione Lampugnano7:45 AMComo, Via Colombo Cristoforo (Grandate FNM)€51One-way0 transfers
Other options
Regionale TRENORD 2551410:43 AM0h46Milan Centrale11:29 AMChiasso station€61One-way0 transfers
Regionale TRENORD 255306:43 PM0h46Milan Centrale7:29 PMChiasso station€61One-way0 transfers
Regionale TRENORD 255327:43 PM0h46Milan Centrale8:29 PMChiasso station€61One-way0 transfers
FlixBus7:25 PM0h50Milano, Autostazione Lampugnano8:15 PMComo, Piazzale San Gottardo (Stazione San Giovanni)€51One-way0 transfers
FlixBus6:35 PM1h40Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:15 PMComo, Piazzale San Gottardo (Stazione San Giovanni)€51One-way0 transfers
FlixBus5:20 PM1h05Milano, Autostazione Lampugnano6:25 PMComo, Piazzale San Gottardo (Stazione San Giovanni)€61One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Milan to Mendrisio
Travel to Mendrisio easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Mendrisio.

This is compared to other travel options from Milan to Mendrisio:
A train is €6 less than a bus for this route with tickets for a bus from Milan to Mendrisio costing on average €12.
Other travel options to Mendrisio take longer:
Bus takes on average 1h 40m.
- Around 36 trains per day.
- Around 20 buses per day.
However, we recommend checking specific travel dates for your route between Milan and Mendrisio as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Milan Centrale and arrive in Chiasso station.
- Buses mostly depart from Ferno, Aeroporto di Milano-Malpensa T1 and arrive in Como, Piazzale San Gottardo (Stazione San Giovanni).
- Travel with Marino Autolinee, Flibco, FlixBus, Itabus to go to Mendrisio by bus.
- Travel with Regionale to go to Mendrisio by train.
- 20 direct buses per day with Marino Autolinee, Flibco, FlixBus, Itabus.
- 21 direct trains per day with Regionale.
Travelling from Milan to Mendrisio: related information
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