Travel Information
Compare bus, train, and flight for Milan to Frosinone
Omio recommends booking the bus as it is the most popular option from Milan to Frosinone among Omio's users. If you are prioritising price, take the train, with an average ticket price of CHF 31 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a train costs an average of CHF 31, while a flight costs an average of CHF 372.
Distance: 336 miles (541 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
CHF 41 Average price | CHF 31 Average price Cheapest | CHF 372 Average price | CHF 162 Average price (fuel + tolls) |
10h 11m Average total duration 9h 41m Onboard + 30m Additional time* | 5h 20m Average total duration 4h 50m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 6h 33m Average total duration (door-to-door) |
0.5 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Milan to Frosinone
Compare the available ways to get from Milan to Frosinone, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Milan to Frosinone:
A train is CHF 11 less than a bus for this route with tickets for a bus from Milan to Frosinone costing on average CHF 41.
A train is CHF 342 less than a flight for this route with tickets for a flight from Milan to Frosinone costing on average CHF 372.
Other travel options to Frosinone take longer:
Train takes on average 5h 20m.
Bus takes on average 10h 11m.
Tickets start at around CHF 41 compared to roughly CHF 162 in fuel and tolls — a saving of about CHF 121. The journey takes 9h 41m versus 6h 33m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Milan to Frosinone
How to get from Milan to Frosinone by train, bus or flight.
Our recommendation
The best way to travel from Milan to Frosinone is by taking a bus because it’s the best combination of price and speed.
241110:00 AM 9h45 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:45 PM Frosinone, Stazione Autobus Frosinone / Piazza Pertini CHF 12 1 One-way 0 transfers
Cheapest
241110:00 AM 9h45 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:45 PM Frosinone, Stazione Autobus Frosinone / Piazza Pertini CHF 12 1 One-way 0 transfers
Fastest
AZ21331:00 PM 1h10 Milan Linate Airport 2:10 PM Rome Leonardo da Vinci Fiumicino Airport CHF 60 1 One-way 0 transfers
Other options
Intercity 597+
Regionale 12586 · Regionale 346651:48 PM 9h52 Milan Centrale 11:40 PM Frosinone station CHF 48 1 One-way 2 transfers
InterCityNotte 797+
Regionale Veloce 4093 · Regionale 233639:13 PM 9h55 Milan Porta Garibaldi 7:08 AM Frosinone station CHF 52 1 One-way 2 transfers
Regionale Veloce TTPER 2455+
Intercity 584+
Regionale 58397:20 AM 10h36 Milan Centrale 5:56 PM Frosinone station CHF 55 1 One-way 2 transfers
24119:10 AM 10h35 Milano, Autostazione Lampugnano 7:45 PM Frosinone, Stazione Autobus Frosinone / Piazza Pertini CHF 12 1 One-way 0 transfers
24219:35 PM 9h04 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 6:39 AM Frosinone, Stazione Autobus Frosinone / Piazza Pertini CHF 16 1 One-way 0 transfers
FlixBus · FlixBus2:25 AM 11h25 Milano, Autostazione Lampugnano 1:50 PM Frosinone, Stazione Autobus Frosinone / Piazza Pertini CHF 27 1 One-way 1 transfer
AZ20492:00 PM 1h10 Milan Linate Airport 3:10 PM Rome Leonardo da Vinci Fiumicino Airport CHF 60 1 One-way 0 transfers
AZ20713:00 PM 1h10 Milan Linate Airport 4:10 PM Rome Leonardo da Vinci Fiumicino Airport CHF 60 1 One-way 0 transfers
AZ2071+
Regionale 20703 · Regionale 12723 · Regionale 126373:00 PM 4h50 Milan Linate Airport 7:50 PM Frosinone station CHF 71 1 One-way 3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Milan to Frosinone
Travel to Frosinone easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Frosinone.

This is compared to other travel options from Milan to Frosinone:
A train is CHF 11 less than a bus for this route with tickets for a bus from Milan to Frosinone costing on average CHF 41.
A train is CHF 342 less than a flight for this route with tickets for a flight from Milan to Frosinone costing on average CHF 372.
Other travel options to Frosinone take longer:
Train takes on average 5h 20m.
Bus takes on average 10h 11m.
- Around 55 trains per day.
- Around 50 flights per day.
- Around 12 buses per day.
However, we recommend checking specific travel dates for your route between Milan and Frosinone as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Linate Airport and arrive in Rome Leonardo da Vinci Fiumicino Airport.
- Trains mostly depart from Milan Centrale and arrive in Frosinone station.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Frosinone, Stazione Autobus Frosinone / Piazza Pertini.
- Travel with ITA, British Airways, Malta Air, Lufthansa, easyJet, Aeroitalia, Austrian Airlines, Ryanair, Bulgaria Air, Lufthansa City Airlines, Brussels Airlines, Eurowings, Avion Express Malta, Neos Air, Swiss, Air Dolomiti to go to Frosinone by flight.
- Travel with FlixBus, Itabus, Marino Autolinee to go to Frosinone by bus.
- Travel with Italo, Frecciarossa, Intercity, Intercity Notte, Regionale to go to Frosinone by train.
- 19 direct flights per day with ITA, Malta Air, easyJet, Aeroitalia, Ryanair, Neos Air.
- 1 direct trains per day with Frecciarossa.
- 7 direct buses per day with FlixBus, Itabus, Marino Autolinee.
Travelling from Milan to Frosinone: related information
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