Travel Information
Compare train, bus, and flight for Lyon to Heidelberg
Omio recommends booking the train as it is the most popular option from Lyon to Heidelberg among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €52 For those with little time, consider booking a flight, which has an average total journey time of 4h 39m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of €52, while a flight costs an average of €384.
Distance: 310 miles (499 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€108 Average price | €52 Average price Cheapest | €384 Average price | €133 Average price (fuel + tolls) |
5h 59m Average total duration 5h 29m Onboard + 30m Additional time* | 11h 27m Average total duration 10h 57m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 2h 39m Onboard + 2h 0m Additional time* | 6h 32m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Lyon to Heidelberg
Compare the available ways to get from Lyon to Heidelberg, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Lyon to Heidelberg:
A bus is €56 less than a train for this route with tickets for a train from Lyon to Heidelberg costing on average €108.
A bus is €332 less than a flight for this route with tickets for a flight from Lyon to Heidelberg costing on average €384.
Other travel options to Heidelberg take longer:
Train takes on average 5h 59m.
Bus takes on average 11h 27m.
The journey is about 1h 3m faster (5h 29m by train vs 6h 32m by car) and roughly €26 cheaper once you factor in fuel and tolls (€108 vs €133). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Lyon to Heidelberg
How to get from Lyon to Heidelberg by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Heidelberg is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus2:20 AM 13h00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 3:20 PM Heidelberg, Hauptbahnhof €36 1 One-way 1 transfer
Cheapest
FlixBus · FlixBus2:20 AM 13h00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 3:20 PM Heidelberg, Hauptbahnhof €36 1 One-way 1 transfer
Fastest
LH45952:50 PM 1h25 Lyon Saint Exupery Airport 4:15 PM Frankfurt am Main Airport €200 1 One-way 0 transfers
Other options
S3+
TGV 958310:01 AM 5h45 Lyon Part Dieu 3:46 PM Heidelberg Hbf €50 1 One-way 1 transfer
FlixBus · FlixBus7:30 AM 14h05 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 9:35 PM Heidelberg, Hauptbahnhof €36 1 One-way 1 transfer
FlixBus · FlixBus5:40 PM 15h30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 9:10 AM Heidelberg, Hauptbahnhof €36 1 One-way 1 transfer
FlixBus · FlixBus10:00 PM 16h00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 2:00 PM Heidelberg, Hauptbahnhof €36 1 One-way 1 transfer
KL1426 · KL1817+
ICE 517 · S36:15 AM 7h30 Lyon Saint Exupery Airport 1:45 PM Heidelberg Hbf €133 1 One-way 3 transfers
KL1426 · KL1817+
ICE 107 · 192776:15 AM 8h33 Lyon Saint Exupery Airport 2:48 PM Heidelberg Hbf €133 1 One-way 3 transfers
KL1426 · KL1817+
ICE 611 · S36:15 AM 11h30 Lyon Saint Exupery Airport 5:45 PM Heidelberg Hbf €133 1 One-way 3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Heidelberg
Travel to Heidelberg easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Heidelberg.

This is compared to other travel options from Lyon to Heidelberg:
A bus is €56 less than a train for this route with tickets for a train from Lyon to Heidelberg costing on average €108.
A bus is €332 less than a flight for this route with tickets for a flight from Lyon to Heidelberg costing on average €384.
Other travel options to Heidelberg take longer:
Train takes on average 5h 59m.
Bus takes on average 11h 27m.
- Around 46 flights per day.
- Around 6 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Heidelberg as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Heidelberg Hbf.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Heidelberg, Hauptbahnhof.
- Travel with TGV, SNCF | TGV INOUI to go to Heidelberg by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Heidelberg by bus.
- Travel with KLM, Lufthansa, Air France, Austrian Airlines, British Airways, Air Dolomiti, Air Baltic, Lufthansa Cityline, KLM Cityhopper, Lot Polish Airlines, Brussels Airlines, Lufthansa City Airlines, CitizenPlane, Helvetic Airways, BA Euroflyer to go to Heidelberg by flight.
- 0 direct trains per day with SNCF | TGV INOUI.
- 4 direct flights per day with Lufthansa, Air Dolomiti, CitizenPlane.
Travelling from Lyon to Heidelberg: related information
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