Travel Information
Compare train, bus, and flight for Lille to Grenoble
Omio recommends booking the train as it is the most popular option from Lille to Grenoble among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $74 For those with little time, consider booking a flight, which has an average total journey time of 3h 18m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $74, while a train costs an average of $152.
Distance: 395 miles (637 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$152 Average price | $74 Average price Cheapest | $126 Average price | $251 Average price (fuel + tolls) |
4h 54m Average total duration 4h 24m Onboard + 30m Additional time* | 11h 36m Average total duration 11h 6m Onboard + 30m Additional time* | 3h 18m Average total duration Fastest 1h 18m Onboard + 2h 0m Additional time* | 7h 39m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Lille to Grenoble
Compare the available ways to get from Lille to Grenoble, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Lille to Grenoble:
A bus is $53 less than a flight for this route with tickets for a flight from Lille to Grenoble costing on average $126.
A bus is $79 less than a train for this route with tickets for a train from Lille to Grenoble costing on average $152.
Other travel options to Grenoble take longer:
Train takes on average 4h 54m.
Bus takes on average 11h 36m.
The journey is about 3h 15m faster (4h 24m by train vs 7h 39m by car) and roughly $100 cheaper once you factor in fuel and tolls ($152 vs $251). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Lille to Grenoble
How to get from Lille to Grenoble by train, bus or flight.
Our recommendation
The best way to travel from Lille to Grenoble is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus6:00 AM 12h40 Lille, Boulevard de Turin (Gare Lille Europe) 6:40 PM Grenoble, Rue Emile Gueymard (Gare Routière) $58 1 One-way 2 transfers
Cheapest
FlixBus · FlixBus · FlixBus6:00 AM 12h40 Lille, Boulevard de Turin (Gare Lille Europe) 6:40 PM Grenoble, Rue Emile Gueymard (Gare Routière) $58 1 One-way 2 transfers
Fastest
5102+
176115:57 AM 4h42 Lille-Europe 10:39 AM Gare de Grenoble $95 1 One-way 1 transfer
Other options
12510+
331487:23 AM 5h07 Lille-Europe 12:30 PM Grenoble Gare Routière $103 1 One-way 1 transfer
7030 · 691911:39 AM 6h34 Lille Flandres 6:13 PM Gare de Grenoble $113 1 One-way 1 transfer
7014 · 69118:12 AM 5h01 Lille Flandres 1:13 PM Gare de Grenoble $117 1 One-way 1 transfer
FlixBus · FlixBus7:50 PM 12h55 Lille, Boulevard de Turin (Gare Lille Europe) 8:45 AM Grenoble, Rue Emile Gueymard (Gare Routière) $58 1 One-way 1 transfer
FlixBus · FlixBus · FlixBus3:00 AM 12h15 Lille, Boulevard de Turin (Gare Lille Europe) 3:15 PM Grenoble, Rue Emile Gueymard (Gare Routière) $59 1 One-way 2 transfers
FlixBus · FlixBus4:30 AM 12h30 Lille, Boulevard de Turin (Gare Lille Europe) 5:00 PM Grenoble, Rue Emile Gueymard (Gare Routière) $59 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lille to Grenoble
Travel to Grenoble easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lille to Grenoble.

This is compared to other travel options from Lille to Grenoble:
A bus is $53 less than a flight for this route with tickets for a flight from Lille to Grenoble costing on average $126.
A bus is $79 less than a train for this route with tickets for a train from Lille to Grenoble costing on average $152.
Other travel options to Grenoble take longer:
Train takes on average 4h 54m.
Bus takes on average 11h 36m.
- Around 10 trains per day.
- Around 9 buses per day.
- Around 1 flights per day.
However, we recommend checking specific travel dates for your route between Lille and Grenoble as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lille Airport and arrive in Geneva International Airport.
- Trains mostly depart from Lille-Europe and arrive in Gare de Grenoble.
- Buses mostly depart from Lille, Boulevard de Turin (Gare Lille Europe) and arrive in Grenoble, Rue Emile Gueymard (Gare Routière).
- Travel with FlixBus, BlaBlaCar Bus to go to Grenoble by bus.
- Travel with easyJet to go to Grenoble by flight.
- Travel with SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Grenoble by train.
- 1 direct flights per day with easyJet.
Travelling from Lille to Grenoble: related information
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