The cheapest and fastest trains from Louisville, KY to Buffalo, NY
Cheapest price
$242
Average price
$242
Fastest journey
1 d 53 m
Average duration
1 d 53 m
Trains per day
1
Distance
776 km
The best way to find a cheap train ticket from Louisville, KY to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Louisville, KY to Buffalo, NY will cost around $242 if you buy it on the day, but the cheapest tickets can be found for only $242.
Of the 1 trains that leave Louisville, KY for Buffalo, NY on Wed, Dec 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Dec 17 the direct trains cover the 776 km distance in an average of 1 d 53 m but if you time it right, some trains will get you there in just 1 d 53 m .
On Wed, Dec 17 the slowest trains will take 1 d 53 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Louisville, KY to Buffalo, NY
Omio recommends booking the flight as it is the most popular option from Louisville, KY to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from €70. For those with little time consider booking a flight which can get you there in 3h 18m. The ticket price range depends on the travel mode: a bus costs an average of €70, and a flight costs an average of €106.
Distance: 482 miles (776 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€181 Average price | €313 Average price | €115 Average price Cheapest |
18h 8m Average total duration 17h 38m Onboard + 30m Additional time* | 6h 18m Average total duration Fastest 3h 18m Onboard + 3h 0m Additional time* | 13h 15m Average total duration 12h 45m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Live departures
Louisville, KY to Buffalo, NY train times
The table below shows live departures for Louisville, KY to Buffalo, NY trains for tomorrow, Wednesday, December 17. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:00 PM Louisville, KY | 24h53 | 12:53 PM Buffalo, NY | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Louisville, KY to Buffalo, NY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 17
Dec 18
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Dec 20
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Dec 23
Why should you book Louisville to Buffalo trains with Omio?
Amtrak operates all train services from Louisville to Buffalo. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Louisville to Buffalo.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Louisville to Buffalo.
Journey information
Overview: Train from Louisville, KY to Buffalo, NY
Trains from Louisville, KY to Buffalo, NY run on average 2 times per day, taking around 17h 38m. Cheap train tickets for this journey start at $177 (€141) but you can travel from only $87 (€70) by bus.
The earliest train runs at 08:00, the last at 08:10. The fastest train covers the 482 miles (776 km) distance in 24h 53m.
Distance 482 miles (776 km) |
Average train duration 17h 38m |
Cheapest ticket price $177 (€141) |
Trains per day 2 |
Fastest train 24h 53m |
First train 08:00 |
Last train 08:10 |
Train companies: Amtrak from Louisville, KY to Buffalo, NY trainsAmtrak trains will get you between Louisville, KY and Buffalo, NY from $87 (€70). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Louisville, KY to Buffalo, NY
Find answers to the most common questions about traveling from Louisville, KY to Buffalo, NY by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Louisville, KY to Buffalo, NY
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