Indianapolis, IN to Cape Girardeau, MO train

Thu, Feb 26
+ Add return
Deutsche Bahn
Regionale
iryo
Ouigo
Italo
1,000+ travel companies
Deutsche Bahn
Regionale
iryo
Ouigo
Italo
1,000+ travel companies
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Compare prices and tickets Indianapolis, IN to Cape Girardeau, MO by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Feb 26
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Feb 28
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Journey information

Overview: Train from Indianapolis, IN to Cape Girardeau, MO

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Take a train from Indianapolis, IN to Cape Girardeau, MO and enjoy the approximately 248 miles (400 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 03:16, the last at 07:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $92 (€74)
Distance
248 miles (400 km)
First train
03:16
Last train
07:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $92 (€74)

FAQs: Trains from Indianapolis, IN to Cape Girardeau, MO

Find answers to the most common questions about traveling from Indianapolis, IN to Cape Girardeau, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Cape Girardeau, MO, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from Indianapolis, IN to Cape Girardeau, MO is 248 miles (400 km).
The first train from Indianapolis, IN to Cape Girardeau, MO leaves at 3:16 AM.
The last train from Indianapolis, IN to Cape Girardeau, MO leaves at 7:30 AM.
Unfortunately, there is no night train available from Indianapolis, IN to Cape Girardeau, MO.
The cheapest way to get from Indianapolis, IN to Cape Girardeau, MO is by bus, with a cost of around $92 (€74).
The train journey from Indianapolis, IN to Cape Girardeau, MO offers views of the Midwest's rural landscapes, including rolling hills, farmland, and small towns, providing a peaceful and scenic experience.
A two to three-day trip is generally sufficient to explore the main attractions of Cape Girardeau, MO, including its historic downtown, riverfront, and local museums.
No, you cannot take the train from Indianapolis, IN to Cape Girardeau, MO.

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