Indianapolis, IN to Cape Girardeau, MO train

Fri, Nov 07
+ Add return
Regionale
Deutsche Bahn
Italo
iryo
Frecciarossa
1,000+ travel companies
Regionale
Deutsche Bahn
Italo
iryo
Frecciarossa
1,000+ travel companies
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Journey information

Overview: Train from Indianapolis, IN to Cape Girardeau, MO

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Take a train from Indianapolis, IN to Cape Girardeau, MO and enjoy the approximately 248 miles (400 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 03:16, the last at 07:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
248 miles (400 km)
First train
03:16
Last train
07:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Trains from Indianapolis, IN to Cape Girardeau, MO

Find answers to the most common questions about traveling from Indianapolis, IN to Cape Girardeau, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Cape Girardeau, MO, this guide helps you travel smarter and with confidence.

FAQs
A two to three-day trip is generally sufficient to explore the main attractions of Cape Girardeau, MO, including its historic downtown, riverfront, and local museums.
The distance by train from Indianapolis, IN to Cape Girardeau, MO is 248 miles (400 km).
The last train from Indianapolis, IN to Cape Girardeau, MO leaves at 7:30 AM.
The first train from Indianapolis, IN to Cape Girardeau, MO leaves at 3:16 AM.
No, you cannot take the train from Indianapolis, IN to Cape Girardeau, MO.
Unfortunately, there is no night train available from Indianapolis, IN to Cape Girardeau, MO.
The train journey from Indianapolis, IN to Cape Girardeau, MO offers views of the Midwest's rural landscapes, including rolling hills, farmland, and small towns, providing a peaceful and scenic experience.

Most popular train connections from Indianapolis, IN

More options for your journey from Indianapolis, IN to Cape Girardeau, MO

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Most popular train connections to Cape Girardeau, MO

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