- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$0.00
Average price
$224
Fastest journey
7 h 26 m
Average duration
7 h 26 m
Trains per day
22
Distance
510 km
The best way to find a cheap train ticket from Frankfurt Airport long-distance station to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Frankfurt Airport long-distance station to Milan Centrale without transferring at least 4 times.
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Omio recommends booking the flight as it is the most popular option from Frankfurt Airport long-distance station to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 1h 14m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a train costs an average of $159.
Distance: 316 miles (510 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$292 Average price | $171 Average price | $51 Average price Cheapest | $190 Average price (fuel + tolls) |
7h 38m Average total duration 7h 8m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* | 11h 2m Average total duration 10h 32m Onboard + 30m Additional time* | 7h 29m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt Airport long-distance station to Milan Centrale:
A bus is $121 (€99) less than a flight for this route with tickets for a flight from Frankfurt Airport long-distance station to Milan Centrale costing on average $171 (€140).
A bus is $241 (€197) less than a train for this route with tickets for a train from Frankfurt Airport long-distance station to Milan Centrale costing on average $292 (€239).
Other travel options to Milan Centrale take longer:
Train takes on average 7h 8m.
Bus takes on average 10h 32m.
You'll arrive about 21m sooner (7h 8m by train vs 7h 29m by car). Tickets start at around $292 (€239) compared to roughly $190 (€156) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Frankfurt Airport long-distance station to Milan Centrale trains for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:46 AM Frankfurt Airport long-distance station | 8h31 | 11:17 AM Milan Centrale | 5 transfers | |
![]() | 2:46 AM Frankfurt Airport long-distance station | 9h31 | 12:17 PM Milan Centrale | 4 transfers | |
![]() | 2:51 AM Frankfurt Airport long-distance station | 9h26 | 12:17 PM Milan Centrale | 5 transfers | |
![]() | 2:51 AM Frankfurt Airport long-distance station | 11h26 | 2:17 PM Milan Centrale | 4 transfers | |
![]() | 6:51 AM Frankfurt Airport long-distance station | 7h26 | 2:17 PM Milan Centrale | 5 transfers | |
![]() | 6:51 AM Frankfurt Airport long-distance station | 8h26 | 3:17 PM Milan Centrale | 4 transfers | |
![]() | 7:51 AM Frankfurt Airport long-distance station | 7h26 | 3:17 PM Milan Centrale | 5 transfers | |
![]() | 7:51 AM Frankfurt Airport long-distance station | 8h26 | 4:17 PM Milan Centrale | 4 transfers | |
![]() | 8:51 AM Frankfurt Airport long-distance station | 7h26 | 4:17 PM Milan Centrale | 5 transfers | |
![]() | 8:51 AM Frankfurt Airport long-distance station | 8h26 | 5:17 PM Milan Centrale | 4 transfers | |
![]() | 9:51 AM Frankfurt Airport long-distance station | 7h26 | 5:17 PM Milan Centrale | 5 transfers | |
![]() | 10:51 AM Frankfurt Airport long-distance station | 7h26 | 6:17 PM Milan Centrale | 4 transfers | |
![]() | 11:51 AM Frankfurt Airport long-distance station | 7h26 | 7:17 PM Milan Centrale | 5 transfers | |
![]() | 11:51 AM Frankfurt Airport long-distance station | 8h26 | 8:17 PM Milan Centrale | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Frankfurt Airport long-distance station to Milan Centrale run on average 2 times per day, taking around 7h 8m. Cheap train tickets for this journey start at $159 (€130) but you can travel from only $23 (€19) by flight.
The earliest train runs at 00:55, the last at 18:51. The fastest train covers the 316 miles (510 km) distance in 7h 26m.
Distance 316 miles (510 km) |
Average train duration 7h 8m |
Cheapest ticket price $159 (€130) |
Trains per day 2 |
Fastest train 7h 26m |
First train 12:55 AM |
Last train 6:51 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Sat |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.
A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.
Milan’s central square and the city’s main gathering point, ideal for first-time visitors and iconic city views.
A charming historic district known for elegant streets, art atmosphere, boutiques, and a classic Milanese walking experience.
Milan’s canal district, very popular for waterside walks, photos, and lively urban atmosphere, especially in the evening.
Milan’s signature saffron risotto, rich with butter and cheese, celebrated for its golden color and elegant, comforting flavor.
A classic Milanese breaded veal cutlet, traditionally cooked in butter and prized as one of the city’s most iconic dishes.
Braised veal shank, often served with risotto alla Milanese, valued for its tender meat and rich marrow-filled sauce.
Long-standing fine dining destination and one of Milan’s best-known vegetarian restaurants, refined and creative in style.
Well-known Milanese restaurant with a modern approach to Lombard classics such as risotto and mondeghili in a stylish setting.
Historic traditional trattoria known for classic Milanese dishes, old-world atmosphere, and a strong local reputation.
Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Frankfurt Airport long-distance station to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

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