The cheapest and fastest trains from Florence Santa Maria Novella to Messina Centrale
Cheapest price
$132
Average price
$158
Fastest journey
9 h 35 m
Average duration
12 h 10 m
Trains per day
6
Distance
719 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Messina Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Messina Centrale will cost around $158 if you buy it on the day, but the cheapest tickets can be found for only $132.
It's difficult to get from Florence Santa Maria Novella to Messina Centrale without transferring at least once.
Intercity 581 · Intercity 551 · Intercity 727
Treno 18251 effettuato con bus FI655+
InterCityNotte 799+
Intercity 723
FRECCIAROSSA 1000 9503+
Intercity 723
Regionale Veloce 4085+
Intercity 594+
InterCityNotte 1959
FRECCIAROSSA 1000 9563+
InterCityNotte 1959
FRECCIAROSSA 1000 9503+
Intercity 723
FRECCIAROSSA 1000 9431+
InterCityNotte 1955
FRECCIAROSSA 1000 9563+
InterCityNotte 1959
Intercity 581 · Intercity 551 · Intercity 727
Treno 18251 effettuato con bus FI655+
InterCityNotte 799+
Intercity 723Travel Information
Compare bus and train for Florence Santa Maria Novella to Messina Centrale
Omio recommends booking the bus as it is the most popular option from Florence Santa Maria Novella to Messina Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a train which can get you there in 10h 40m. The ticket price range depends on the travel mode: a bus costs an average of €28, and a train costs an average of €55.
Distance: 446 miles (719 km)
Compare train with
| Train | Most popular Bus |
|---|---|
€99 Average price | €67 Average price Cheapest |
11h 10m Average total duration Fastest 10h 40m Onboard + 30m Additional time* | 15h 24m Average total duration 14h 54m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Messina Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Messina Centrale trains for today, Sunday, February 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18783+ Intercity 594+ InterCityNotte 1959 | 5:20 PM Florence Santa Maria Novella | 13h45 | 7:05 AM Messina Centrale | 2 transfers | |
FRECCIAROSSA 1000 9555+ InterCityNotte 1955 | 6:14 PM Florence Santa Maria Novella | 10h01 | 4:15 AM Messina Centrale | 1 transfer | |
FRECCIAROSSA 9435+ InterCityNotte 1959 | 7:48 PM Florence Santa Maria Novella | 11h17 | 7:05 AM Messina Centrale | 1 transfer | |
Treno 18251 effettuato con bus FI655+ InterCityNotte 799+ Intercity 723 | 11:40 PM Florence Santa Maria Novella | 14h55 | 2:35 PM Messina Centrale | 2 transfers | |
| Monday, February 23 | |||||
Intercity 581 · Intercity 551 · Intercity 727 | 4:45 AM Florence Santa Maria Novella | 13h50 | 6:35 PM Messina Centrale | 2 transfers | |
FRECCIAROSSA 1000 9503+ Intercity 723 | 5:00 AM Florence Santa Maria Novella | 9h35 | 2:35 PM Messina Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Messina Centrale by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 23
Feb 24
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Journey information
Overview: Train from Florence Santa Maria Novella to Messina Centrale
Trains from Florence Santa Maria Novella to Messina Centrale run on average 5 times per day, taking around 10h 40m. Cheap train tickets for this journey start at $69 (€55) but you can travel from only $36 (€28) by bus.
The earliest train runs at 04:45, the last at 23:40. The fastest train covers the 446 miles (719 km) distance in 13h 43m.
Distance 446 miles (719 km) |
Average train duration 10h 40m |
Cheapest ticket price $69 (€55) |
Trains per day 5 |
Fastest train 13h 43m |
First train 04:45 |
Last train 23:40 |
Train companies: Intercity Notte, Intercity from Florence Santa Maria Novella to Messina Centrale trainsIntercity Notte, Intercity trains will get you between Florence Santa Maria Novella and Messina Centrale from $36 (€28). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
FAQs: Trains from Florence Santa Maria Novella to Messina Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Messina Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Messina Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Messina Centrale
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Messina Centrale
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