- Must visit
Des Moines Art Center
Leading contemporary and modern art museum with notable architecture and a respected permanent collection; a top cultural stop in the city.
Flights from San Antonio, TX to Des Moines, IA depart on average 44 times per day, taking around 3h 18m. Cheap flight tickets for this journey start at $218 (€176) if you book in advance.
The earliest flight runs at 05:00, the last at 20:08. The fastest flight covers the 884 miles (1424 km) distance in 6h 14m. May is the cheapest month to fly.
Distance 884 miles (1424 km) |
Average flight duration 3h 18m |
Cheapest ticket price $218 (€176) |
Flights per day 44 |
Fastest flight 6h 14m |
First flight 5:00 AM |
Last flight 8:08 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Cheapest price
$218
Average price
$218
Fastest journey
7 h 47 m
Average duration
7 h 47 m
Flights per day
1
Distance
1424 km
The best way to find a cheap flight ticket from San Antonio, TX to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Des Moines, IA will cost around $218 if you buy it on the day, but the cheapest tickets can be found for only $218.
Of the 1 flights that leave San Antonio, TX for Des Moines, IA onTue, May 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct flights cover the 1424 km distance in an average of 7 h 47 m but if you time it right, some flights will get you there in just 7 h 47 m .
On Tue, May 19 the longest flights will take 7 h 47 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from San Antonio, TX to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $250. For those with little time consider booking a flight which can get you there in 3h 18m. The ticket price range depends on the travel mode: a bus costs an average of $250, and a flight costs an average of $218.
Distance: 884 miles (1424 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$438 Average price | $250 Average price Cheapest | $195 Average price (fuel + tolls) |
6h 18m Average total duration Fastest 3h 18m Onboard + 3h 0m Additional time* | 44h 50m Average total duration 44h 20m Onboard + 30m Additional time* | 14h 27m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Des Moines, IA:
A bus is $188 (€151) less than a flight for this route with tickets for a flight from San Antonio, TX to Des Moines, IA costing on average $438 (€353).
Other travel options to Des Moines, IA take longer:
Bus takes on average 44h 20m.
The table below shows live departures for San Antonio, TX to Des Moines, IA flights for tomorrow, Tuesday, May 19. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:17 AM San Antonio, TX | 7h47 | 7:04 PM Des Moines, IA | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Des Moines — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines trip today.
Leading contemporary and modern art museum with notable architecture and a respected permanent collection; a top cultural stop in the city.
Museum covering Iowa history through statewide exhibits, artifacts, and rotating displays inside the State Historical Building.
Historic house museum with art, rare books, and grand interiors inspired by English manor architecture; well known for tours and events.
Lively historic district east of the river known for independent shops, murals, restored storefronts, and easy access to the Capitol.
Downtown riverfront walking route with bridges, public art, events spaces, and some of the city’s best skyline perspectives.
Popular urban park with a large lake, illuminated pedestrian bridge, and scenic path favored for walks and sunset views.
An Iowa classic featuring a breaded, fried pork tenderloin cutlet served on a bun, often comically larger than the bread. It is one of the state’s most iconic comfort foods.
Iowa sweet corn is a summer staple, prized for its freshness and sweetness. Locals eat it boiled or grilled with butter at fairs, backyard cookouts, and seasonal farm stands.
A seasoned ground beef sandwich served loose on a bun rather than formed into a patty. It is a longtime Midwestern lunch counter favorite found across Iowa.
A respected fine-dining spot in a historic house, serving Italian-influenced cuisine with a romantic atmosphere and strong local reputation.
An established upscale steakhouse known for prime steaks, seafood, and polished service in an elegant downtown setting.
A well-known contemporary American restaurant in the East Village, popular for refined seasonal dishes and a stylish but approachable atmosphere.
Generally affordable by major U.S. city standards. Hotels and dining are usually moderate, with good budget options.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few USD.
Find answers to the most common questions about traveling from San Antonio, TX to Des Moines, IA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

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