- Must visit
Art Institute Of Chicago
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
Flights from Myrtle Beach, SC to Chicago, IL depart on average 29 times per day, taking around 3h 37m. Cheap flight tickets for this journey start at $154 (€126) but you can travel from only $131 (€107) by bus.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 738 miles (1189 km) distance in 6h 44m. December is the cheapest month to fly.
Distance 738 miles (1189 km) |
Average flight duration 3h 37m |
Cheapest ticket price $154 (€126) |
Flights per day 29 |
Direct flights 1 |
Fastest flight 6h 44m |
First flight 5:00 AM |
Last flight 10:10 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Cheapest price
$232
Average price
$232
Fastest journey
9 h 37 m
Average duration
9 h 37 m
Flights per day
1
Distance
1189 km
The best way to find a cheap flight ticket from Myrtle Beach, SC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Myrtle Beach, SC to Chicago, IL will cost around $232 if you buy it on the day, but the cheapest tickets can be found for only $232.
Of the 1 flights that leave Myrtle Beach, SC for Chicago, IL onTue, Jul 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jul 07 the direct flights cover the 1189 km distance in an average of 9 h 37 m but if you time it right, some flights will get you there in just 9 h 37 m .
On Tue, Jul 07 the longest flights will take 9 h 37 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Chicago, IL among Omio's users. If you are prioritising price take the flight with prices starting from $154. For those with little time consider booking a flight which can get you there in 3h 37m. The ticket price range depends on the travel mode: a flight costs an average of $154, and a bus costs an average of $131.
Distance: 738 miles (1189 km)
| Flight | Most popular Bus | Driving |
|---|---|---|
$193 Average price Cheapest | $234 Average price | $181 Average price (fuel + tolls) |
6h 37m Average total duration Fastest 3h 37m Onboard + 3h 0m Additional time* | 25h 25m Average total duration 24h 55m Onboard + 30m Additional time* | 14h 35m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Myrtle Beach, SC to Chicago, IL:
A flight is $42 (€34) less than a bus for this route with tickets for a bus from Myrtle Beach, SC to Chicago, IL costing on average $234 (€192).
Other travel options to Chicago, IL take longer:
Bus takes on average 24h 55m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
A top natural history museum known for Sue the T. rex, ancient cultures, fossils, and broad science collections.
A large hands-on science museum with a German submarine, space exhibits, and interactive engineering displays.
Chicago’s signature downtown park, home to Cloud Gate, gardens, public art, and major seasonal events.
The city’s best-known avenue for architecture, shopping, and bustling urban energy along North Michigan Avenue.
A popular pedestrian waterfront with excellent skyline views, bridges, and easy access to boat architecture tours.
A thick, buttery crust pizza baked in a deep pan with layers of cheese, toppings, and chunky tomato sauce. It is one of Chicago’s most iconic and debated local specialties.
An all-beef hot dog on a poppy seed bun topped with yellow mustard, relish, onions, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food served without ketchup.
Thinly sliced seasoned roast beef piled onto an Italian roll, often dipped in its juices and topped with sweet peppers or giardiniera. It is a defining working-class Chicago sandwich.
Chicago’s world-famous fine-dining restaurant known for highly creative tasting menus and theatrical presentation. It offers one of the city’s most celebrated upscale dining experiences.
A beloved casual institution best known for breaded steak sandwiches and hearty Italian-American comfort food. It has a loyal local following and an old-school atmosphere.
A legendary Chicago chain celebrated for buttery-crust deep-dish pizza and a classic casual atmosphere. One of the city’s best-known places to try this signature dish.
Chicago is pricey for hotels and dining, but budget eats and public transit help keep daily costs manageable.
Tip 18-20% at restaurants; 15-20% for taxis and rideshares; USD 1-2 per drink at bars; USD 1-2 per bag for bellhops; USD 2-5 per night for housekeeping.
Find answers to the most common questions about traveling from Myrtle Beach, SC to Chicago, IL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Myrtle Beach, SC to Chicago, IL flights use the Myrtle Beach International Airport to O'Hare International Airport airport pair. Use this guide to compare Myrtle Beach, SC and Chicago, IL airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Myrtle Beach International Airport is 3 km from Myrtle Beach city centre. Public transport options include:
Myrtle Beach International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants include Boardwalk Cafe and cho Hippo, located in the main terminal.
Free Wi-Fi available throughout the airport. ATMs are located in the main terminal near the baggage claim area.
Lost and found is available at the station.
Available at Myrtle Beach International Airport: Parking, Taxis, WC.
Available at Myrtle Beach International Airport: Car Rental.
Accessibility facilities are available at Myrtle Beach International Airport: Elevators, ramps, toilets.
Nearby hotels include Hotels such as Hilton Garden Inn and DoubleTree Resort within walking distance..
O'Hare International Airport is 3 km from Chicago city centre. Public transport options include:
O'Hare International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
Free Wi-Fi available throughout the airport. ATMs are located throughout all terminals.
Lost and found is available at the station.
Available at O'Hare International Airport: Parking, Taxis, WC.
Available at O'Hare International Airport: Car Rental.
Accessibility facilities are available at O'Hare International Airport: Elevators, ramps, toilets.
Nearby hotels include Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby..
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