Journey information
Overview: Mendoza to Santiago flight
Flights from Mendoza to Santiago depart on average 19 times per day, taking around 1h 10m. Cheap flight tickets for this journey start at $77 (€62) but you can travel from only $33 (€27) by bus.
There are 3 flights per day. The earliest flight runs at 00:40, the last at 23:58. The fastest flight covers the 112 miles (181 km) distance in 56m. July is the cheapest month to fly.
Distance 112 miles (181 km) |
Average flight duration 1h 10m |
Cheapest ticket price $77 (€62) |
Flights per day 19 |
Direct flights 3 |
Fastest flight 56m |
First flight 00:40 |
Last flight 23:58 |
Cheapest month Jul |
Cheapest day Thu |
High season Oct - Dec |
Low season Apr - Jun |
Busiest day Thu |
Least busy day Sun |
Best day to book ahead 70 days |
The cheapest and fastest flights from Mendoza to Santiago
Cheapest price
$97
Average price
$112
Fastest journey
56 m
Average duration
1 h 2 m
Flights per day
3
Distance
181 km
The best way to find a cheap flight ticket from Mendoza to Santiago is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mendoza to Santiago will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $97.
Of the 3 flights that leave Mendoza for Santiago onFri, Mar 13, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Mar 13 the direct flights cover the 181 km distance in an average of 1 h 2 m but if you time it right, some flights will get you there in just 56 m .
On Fri, Mar 13 the longest flights will take 1 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus and flight for Mendoza to Santiago
Omio recommends booking the flight as it is the most popular option from Mendoza to Santiago among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a flight which can get you there in 1h 10m. The ticket price range depends on the travel mode: a bus costs an average of $33, and a flight costs an average of $77.
Distance: 112 miles (181 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$111 Average price | $41 Average price Cheapest |
4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 8h 25m Average total duration 7h 55m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Mendoza to Santiago flight times
The table below shows live departures for Mendoza to Santiago flights for today, Wednesday, March 11. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:45 PM Mendoza | 1h05 | 6:50 PM Santiago | 0 transfersDirect | |
![]() | 6:40 PM Mendoza | 1h05 | 7:45 PM Santiago | 0 transfersDirect | |
![]() | 6:50 PM Mendoza | 1h05 | 7:55 PM Santiago | 0 transfersDirect | |
| Thursday, March 12 | |||||
![]() | 12:00 AM Mendoza | 1h05 | 1:05 AM Santiago | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
How far in advance should I book flight tickets from Mendoza to Santiago?
Compare prices and tickets Mendoza to Santiago by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 12
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Why should you book Mendoza to Santiago flights with Omio?
Why book with Omio vs Sky Airline?
- Compare with other providers: On Omio, you can not only buy tickets for Sky Airline, but also compare tickets for the likes of LATAM Airlines, B & H Airlines or Aerolineas Argentinas to find the best option for your trip from Mendoza to Santiago.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Sky Airline with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Mendoza to Santiago.
Why book with Omio over Kayak, Skyscanner or Edreams?
- Compare with other providers: On Omio, you can also compare tickets for the likes of LATAM Airlines, B & H Airlines or Aerolineas Argentinas to find the best option for your trip from Mendoza to Santiago.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Mendoza to Santiago.
Airlines: Sky Airline, LATAM Airlines, B & H Airlines, Aerolineas Argentinas from Mendoza to SantiagoFind the best flights between Mendoza to Santiago with Omio's travel partners Sky Airline, LATAM Airlines, B & H Airlines, Aerolineas Argentinas from $33 (€27). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Aerolineas Argentinas
Sky Airline
LATAM Airlines
B & H Airlines
FAQs: Mendoza to Santiago Flight
Find answers to the most common questions about traveling from Mendoza to Santiago by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santiago, this guide helps you travel smarter and with confidence.

- Fiesta de la Vendimia, a vibrant wine harvest festival celebrating Chile's winemaking heritage with tastings, music, and cultural events
- Santiago a Mil, an international theater festival featuring performances from around the world in various venues across the city
- Fiestas Patrias, Chile's national celebrations with parades, traditional food, and folk music honoring the country's independence.
- Fiestas Patrias, vibrant national celebrations with parades, traditional music, and delicious food
- New Year’s Day, lively festivities and fireworks to welcome the new year in a warm climate
- Easter, a time for cultural and religious observances with beautiful processions.
popular airports
Popular airports from Mendoza to Santiago
- Free Wi-Fi available throughout the airport.
- Shops are available, located in the main terminal, including duty-free and local crafts.
- Parking available near the terminal, approximately 0.95€ ($1) per hour.
- Restaurants are available; located in the main terminal, offering fast food and local cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Lounge available, Aeropuertos VIP Club located in the departures area.
- Lost and Found located in the main terminal near the information desk.
- Car rental services are available; companies like Hertz and Avis are located in the arrivals area.
- Bus line 60, stop Aeropuerto, 11 km
- Free Wi-Fi available throughout the airport.
- Shops include duty-free and local Chilean products, located in both terminals.
- Parking available in several lots, approximately 1.7€ (CLP 1,500) per hour.
- Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby include Holiday Inn Santiago Airport, within walking distance.
- Showers available in VIP lounges; access may require a lounge pass or fee.
- Several lounges available, including LATAM and American Airlines lounges.
- Lost and Found located in the arrivals area.
- Car rental services available from major companies like Hertz and Avis.
- Bus Centropuerto, Pajaritos Station, 19 km
More options for your journey from Mendoza to Santiago
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