- Must visit
Museo Nacional de Bellas Artes
Chile's leading fine arts museum in a landmark 1910 palace. Visit for national and international art plus one of the city's most beautiful interiors.
Flights from Mendoza to Santiago depart on average 6 times per day, taking around 2h 44m. Cheap flight tickets for this journey start at $66 (€54) if you book in advance.
There are 3 flights per day. The earliest flight runs at 00:40, the last at 23:58. The fastest flight covers the 112 miles (181 km) distance in 54m. May is the cheapest month to fly.
Distance 112 miles (181 km) |
Average flight duration 2h 44m |
Cheapest ticket price $66 (€54) |
Flights per day 6 |
Direct flights 3 |
Fastest flight 54m |
First flight 12:40 AM |
Last flight 11:58 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 14 days |
Cheapest price on Sep 17
$137
Average ticket price on Sep 17
$390
Fastest journey on Sep 17
59 m
Average journey duration on Sep 17
7 h 38 m
Flights on Sep 17
4
Distance
181 km
The best way to find a cheap flight ticket from Mendoza to Santiago is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mendoza to Santiago will cost around $390 if you buy it on the day, but the cheapest tickets can be found for only $137.
On Thu, Sep 17, we found 4 flights from Mendoza to Santiago, including 3 direct services.
On Thu, Sep 17 the direct flights cover the 181 km distance in an average of 7 h 38 m but if you time it right, some flights will get you there in just 59 m .
On Thu, Sep 17 the longest flights will take 1 d 3 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
LA435
H2526
LA437
LA782+
LA5977 · LA5945
LA435
LA437
H2526
LA782+
LA5977 · LA5945Omio recommends booking the flight as it is the most popular option from Mendoza to Santiago among Omio's users. If you are prioritising price, take the flight, with an average ticket price of $307 For those with little time, consider booking a flight, which has an average total journey time of 4h 44m. Average ticket prices depend on the travel mode: a flight costs an average of $307, while a flight costs an average of $307.
Distance: 112 miles (181 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$307 Average price Cheapest | $55 Average price (fuel + tolls) | |
4h 44m Average total duration Fastest 2h 44m Onboard + 2h 0m Additional time* | 5h 46m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
The table below shows live departures for Mendoza to Santiago flights for today, Wednesday, September 16. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
LA437 | 7:50 PM Mendoza | 1h00 | 8:50 PM Santiago | 0 transfersDirect | |
| Thursday, September 17 | |||||
LA435 | 11:51 AM Mendoza | 0h59 | 12:50 PM Santiago | 0 transfersDirect | |
H2526 | 3:40 PM Mendoza | 1h01 | 4:41 PM Santiago | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Santiago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santiago trip today.
Chile's leading fine arts museum in a landmark 1910 palace. Visit for national and international art plus one of the city's most beautiful interiors.
Compelling museum on human rights abuses during the dictatorship. Essential for understanding modern Chile through multimedia, testimony, and archives.
Interactive pre-Columbian museum in a restored colonial building. Famous for Andean and Mesoamerican collections and clear, engaging interpretation.
Santiago's historic main square, surrounded by key civic and religious buildings. Ideal for architecture, street life, and starting a downtown walk.
Large urban park and hill complex with trails, gardens, pools, and lookouts. A signature Santiago experience for views and open-air recreation.
Leafy cultural district known for mansions, museums, and cafes nearby. Walk here for elegant architecture, galleries, and a relaxed urban atmosphere.
Empanada de pino is Chile’s classic baked pastry filled with beef, onion, egg, olive, and raisins; a staple for fiestas patrias and everyday bakeries.
Pastel de choclo is a baked corn casserole with sweet corn topping over beef or chicken, onion, olives, and egg; a beloved central Chile comfort dish.
Cazuela is a traditional homemade broth with beef or chicken, pumpkin, potato, corn, and rice; valued as hearty Chilean family cooking.
Refined restaurant in a restored mansion, celebrated for contemporary Chilean cuisine and polished fine dining service.
Traditional Fuente de soda famed for oversized sandwiches, completos, and classic casual Santiago dining.
Well-known neighborhood restaurant serving Chilean staples, seafood, and comforting local dishes in a relaxed setting.
Moderate for South America; hotels cost more than in Lima, but dining and metro stay reasonable for tourists.
A 10% restaurant tip is customary and often suggested on the bill. Round up for cafes and taxis; tipping is not expected for short taxi rides.
Official public transport app
Arturo Merino Benítez Airport -> Plaza de Armas, Santiago
Find answers to the most common questions about traveling from Mendoza to Santiago by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santiago, this guide helps you travel smarter and with confidence.

Most Mendoza to Santiago flights use the Mendoza to Santiago airport pair. Use this guide to compare Mendoza and Santiago airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Mendoza is 6 km from Mendoza city centre. Public transport options include:
Mendoza has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are available; located in the main terminal, offering fast food and local cuisine.
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Lost and found is available at the station.
Available at Mendoza: Parking, Taxis, WC.
Available at Mendoza: Car Rental.
Accessibility facilities are available at Mendoza: Elevators, ramps.
Santiago is 8 km from Santiago city centre. Public transport options include:
Santiago has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
Free Wi-Fi available throughout the airport. ATMs are located in both domestic and intertiol terminals.
Lost and found is available at the station.
Available at Santiago: Parking, Taxis, WC.
Available at Santiago: Car Rental.
Accessibility facilities are available at Santiago: Elevators, ramps.
Nearby hotels include Hotels nearby include Holiday Inn Santiago Airport, within walking distance..
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