Medellín MDE to Chicago, IL CHI flight with Delta Air Lines

United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.

American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.

Avianca is the national and largest airline of Colombia, and one of the oldest airlines in the world, tracing its origins back to 1919. It serves as the flagship of a group of airlines across the Americas, operating under a codesharing system. Avianca boasts an extensive network of destinations throughout the Americas, with its main hub located at El Dorado International Airport in Bogotá. The airline is a member of the Star Alliance, offering various classes of service from economy to business and first-class. Its fleet includes modern aircraft such as the Airbus A320 family, Airbus A330, and Boeing 787 Dreamliner.

LATAM Airlines Peru, a subsidiary of LATAM Airlines Group, is a major airline based in Lima, Peru, and the dominant carrier in the Peruvian domestic market. It operates scheduled domestic and international flights, with its main hub at Jorge Chávez International Airport. The airline was formerly known as LAN Perú S.A. until 2015, when it was dissolved and rebranded as LATAM Airlines as part of the merger between LAN Airlines and TAM Airlines. LATAM Airlines Group, the parent company, is the largest airline group in South America.

Spirit Airlines is an American ultra-low-cost carrier, headquartered in Dania Beach, Florida, operating scheduled flights throughout the United States, the Caribbean, and Latin America. Known for its distinctive bright yellow planes, Spirit's business model traditionally focuses on offering low base fares by unbundling services, allowing passengers to pay only for the amenities they choose, such as baggage and seat selection. As of August 2024, Spirit is evolving its offerings, introducing new fare tiers like "Go Big," "Go Comfy," "Go Savvy," and "Go," which include various bundled perks such as wider seats, extra legroom, priority boarding, and in-flight refreshments. Spirit was the seventh largest passenger carrier in North America as of 2023.