- Must visit
Museo di Civiltà Preclassiche della Murgia Meridionale
Main civic museum presenting local archaeology, art, and history. It is the best introduction to Ostuni’s development from prehistory to today.
Omio recommends booking the bus as it is the most popular option from Vicenza to Ostuni among Omio's users. If you are prioritising price take the train with prices starting from €74. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a train costs an average of €74, and a flight costs an average of €179.
Distance: 451 miles (726 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€114 Average price | €179 Average price | €74 Average price Cheapest | €145 Average price (fuel + tolls) |
20h 45m Average total duration 20h 15m Onboard + 30m Additional time* | 4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 13h 49m Average total duration 13h 19m Onboard + 30m Additional time* | 8h 24m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Vicenza to Ostuni:
A train is €40 less than a bus for this route with tickets for a bus from Vicenza to Ostuni costing on average €114.
A train is €105 less than a flight for this route with tickets for a flight from Vicenza to Ostuni costing on average €179.
Other travel options to Ostuni take longer:
Train takes on average 13h 19m.
Bus takes on average 20h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:55PM | Arrival Time 03:10PM | Duration 20h15 | Departure days Sun | Cheapest price €114 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Vicenza to Ostuni run on average 5 times per day, taking around 20h 15m. Cheap bus tickets for this journey start at €114 but you can travel from only €74 by train.
The earliest bus runs at 00:05, the last at 20:40. The fastest bus covers the 451 miles (726 km) distance in 20h 15m.
Distance 451 miles (726 km) |
Average bus duration 20h 15m |
Cheapest ticket price €114 |
Buses per day 5 |
Fastest bus 20h 15m |
First bus 12:05 AM |
Last bus 8:40 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Ostuni — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Ostuni trip today.
Main civic museum presenting local archaeology, art, and history. It is the best introduction to Ostuni’s development from prehistory to today.
Archaeological section famous for finds linked to the prehistoric 'Woman of Ostuni'. It is essential for understanding the area’s ancient past.
Museum rooms in a former Carmelite convent displaying historical material and temporary exhibits tied to Ostuni’s cultural heritage.
Ostuni’s main square, lined with landmarks and daily life. It is the natural starting point for visiting the White City and people-watching.
The famous whitewashed old quarter of alleys, arches, and stairways. It is Ostuni’s most atmospheric area for wandering and photography.
Panoramic terrace near the cathedral with sweeping views over olive groves to the Adriatic. It is one of the city’s best sunset viewpoints.
Hand-rolled ear-shaped pasta, usually served with tomato sauce, caciocavallo or turnip tops. A Puglian staple found across Ostuni homes and trattorias.
Broad beans puréed until silky and served with wild chicory. A classic peasant dish of Puglia, prized for its simple local ingredients and deep flavor.
Crisp baked bread dough ring made with white wine and olive oil. Traditional in Puglia and perfect with Ostuni aperitivi, cheese, or local wine.
Michelin-starred dining in a refined masseria setting. Known for elegant Puglian tasting menus, polished service, and seasonal local ingredients.
Well-regarded traditional restaurant in Ostuni’s old town. Expect regional pasta, local meats, and Apulian classics in a warm stone-vaulted setting.
Established casual favorite serving wood-fired pizzas and local dishes. Lively atmosphere, dependable quality, and popular with both residents and visitors.
Moderate for Puglia: lodging rises in peak summer, but meals and local transport are usually reasonable versus major Italian tourist cities.
Service is often included or modest. Round up at cafes, leave 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Ostuni, SS379 (Area di Servizio Q8) -> Piazza della Libertà, Ostuni
Find answers to the most common questions about traveling from Vicenza to Ostuni by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Ostuni, this guide helps you travel smarter and with confidence.

Most Vicenza to Ostuni buses use the Vicenza, Autostazione to Ostuni, SS379 (Area di Servizio Q8) station pair, with some services arriving at Ostuni, Viale Dello Sport. Use this guide to compare Vicenza and Ostuni bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need