Tuscaloosa, AL to Lake City, FL bus with Greyhound

Sun, Jun 21
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Tuscaloosa, AL to Lake City, FL

Showing times and prices for Jun 21

Cheapest price

$126

Average price

$126

Fastest journey

1 d 5 h 45 m

Average duration

1 d 5 h 45 m

Buses per day

1

Distance

575 km

Cheap tickets

The best way to find a cheap bus ticket from Tuscaloosa, AL to Lake City, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Tuscaloosa, AL to Lake City, FL will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $126.

Fast buses

It's difficult to get from Tuscaloosa, AL to Lake City, FL without transferring at least 2 times.

  • Greyhound USA
    7:45 AM29h45
    Tuscaloosa, AL
    1:30 PMLake City, FL
    $1261One-way
    2 transfers

Travel Information

Compare bus and flight for Tuscaloosa, AL to Lake City, FL

Omio recommends booking the flight as it is the most popular option from Tuscaloosa, AL to Lake City, FL among Omio's users. If you are prioritising price take the bus with prices starting from $227. For those with little time consider booking a flight which can get you there in 4h 38m. The ticket price range depends on the travel mode: a bus costs an average of $227, and a flight costs an average of $452.

Distance: 357 miles (575 km)

Compare bus with

Bus
Most popular
Flight
Driving

$227

Average price

Cheapest

$452

Average price

$82

Average price

(fuel + tolls)

16h 10m

Average total duration

15h 40m

Onboard

+

30m

Additional time*

7h 38m

Average total duration

Fastest

4h 38m

Onboard

+

3h 0m

Additional time*

6h 43m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Tuscaloosa, AL to Lake City, FL is a bus with an average price of $227 (€186).

This is compared to other travel options from Tuscaloosa, AL to Lake City, FL:

A bus is $225 (€184) less than a flight for this route with tickets for a flight from Tuscaloosa, AL to Lake City, FL costing on average $452 (€370).

The fastest way to travel from Tuscaloosa, AL to Lake City, FL is by flight with an average journey time of 4h 38m.

Other travel options to Lake City, FL take longer:

Bus takes on average 15h 40m.

It's helpful to compare your options as there are 2 ways to travel between Tuscaloosa, AL and Lake City, FL including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Tuscaloosa, AL to Lake City, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Tuscaloosa, AL to Lake City, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:50AM
Arrival Time
05:30PM
Duration
15h40
Departure days
Fri
Cheapest price
$227
Operator
Greyhound USA
Departure Time
07:45AM
Arrival Time
01:30PM
Duration
29h45
Departure days
Tue, Wed, Fri, Sat, Sun
Cheapest price
$126

Live departures

Tuscaloosa, AL to Lake City, FL bus times

The table below shows live departures for Tuscaloosa, AL to Lake City, FL buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound USA7:45 AM Tuscaloosa, AL
29h45
1:30 PM Lake City, FL2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Tuscaloosa, AL to Lake City, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27

Why should you book Tuscaloosa, AL to Lake City, FL buses with Omio?

Greyhound operates all buses services from Tuscaloosa, AL to Lake City, FL.
Omio is an official ticket reseller for all your travel options from Tuscaloosa, AL to Lake City, FL.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Tuscaloosa, AL to Lake City, FL.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Tuscaloosa, AL to Lake City, FL.

Journey information

Overview: Bus from Tuscaloosa, AL to Lake City, FL

USAUSA
USAUSA
Icon of bus

Buses from Tuscaloosa, AL to Lake City, FL run on average 2 times per day, taking around 15h 40m. Cheap bus tickets for this journey start at $227 (€186) if you book in advance.

The earliest bus runs at 01:50, the last at 01:50. The fastest bus covers the 357 miles (575 km) distance in 15h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
357 miles (575 km)
Average bus duration
15h 40m
Cheapest ticket price
$227 (€186)
Buses per day
2
Fastest bus
15h 40m
First bus
1:50 AM
Last bus
1:50 AM
Cheapest Month
Apr
Cheapest Day
Thu
High Season
Apr - Jun
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Tuscaloosa, AL to Lake City, FLYou can travel by bus between Tuscaloosa, AL to Lake City, FL with Greyhound for as low as $227 (€186). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
15h 40m
Cheapest Price
$227 (€186)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Tuscaloosa, AL to Lake City, FL

Find answers to the most common questions about traveling from Tuscaloosa, AL to Lake City, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lake City, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Tuscaloosa, AL to Lake City, FL can start from as little as $227 (€186) when you book in advance. The average bus ticket price for Tuscaloosa, AL to Lake City, FL is $227 (€186) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tuscaloosa, AL to Lake City, FL is 15h 40m to travel the 357 miles (575 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tuscaloosa, AL to Lake City, FL leaves at 1:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tuscaloosa, AL to Lake City, FL leaves at 1:50 AM.
There are 2 buses a day from Tuscaloosa, AL to Lake City, FL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Tuscaloosa, AL to Lake City, FL, you can count on Greyhound for the best way to get you to Lake City, FL. You can also check all possible bus companies who offer a service between Tuscaloosa, AL and Lake City, FL and compare the amenities they offer before buying a bus ticket.
A trip to Lake City, FL from Tuscaloosa, AL is worth doing but not as a day trip with a journey time of 15h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tuscaloosa, AL to Lake City, FL is April.
It's helpful to compare your options as there are 2 ways to travel between Tuscaloosa, AL and Lake City, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Tuscaloosa, AL to Lake City, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Tuscaloosa, AL to Lake City, FL for bus company Greyhound.
Whether you can cancel your bus ticket from Tuscaloosa, AL to Lake City, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Tuscaloosa, AL to Lake City, FL.
Yes, the following luggage options are included when booking a bus ticket from Tuscaloosa, AL to Lake City, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Tuscaloosa, AL to Lake City, FL:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Tuscaloosa, AL to Lake City, FL.
You can reserve your seat on the bus from Tuscaloosa, AL to Lake City, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Tuscaloosa, AL to Lake City, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Tuscaloosa, AL to Lake City, FL with the following bus company: Greyhound.
Since neither Tuscaloosa, AL nor Lake City, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Tuscaloosa, AL to Lake City, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Lake City, FL, travelers should be cautious of petty theft and vehicle break-ins, especially in parking areas near popular attractions. It's advisable to avoid poorly lit or isolated areas at night. Common scams include overpriced services or unofficial tour operators; always use licensed providers for transportation and activities. Staying alert and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Tuscaloosa, AL to Lake City, FL

Most Tuscaloosa, AL to Lake City, FL buses use the Tuscaloosa, Greensboro Ave (Bus Station) to Lake City, S Marion Ave (Lake City Greyhound Station) station pair. Use this guide to compare Tuscaloosa, AL and Lake City, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Tuscaloosa
Arrival bus stations in Lake City
Tuscaloosa, Greensboro Ave (Bus Station)

Most popular bus connections from Tuscaloosa, AL

Bus Tuscaloosa, AL - Birmingham, AL
Bus Tuscaloosa, AL - Atlanta, GA

Most popular buses to and from Lake City, FL and Tuscaloosa, AL

Bus Orlando, FL - Lake City, FL
Bus Tuscaloosa, AL - New York, NY
HomeBusesBuses in USATuscaloosa, AL to Lake City, FL bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone