- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Buses from Potsdam to Prague run on average 3 times per day, taking around 8h 30m. Cheap bus tickets for this journey start at $36 but you can travel from only $28 by train.
The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 170 miles (274 km) distance in 7h 0m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Potsdam to Prague.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 08:00AM | Duration 7h35 | Departure days Wed | Cheapest price $37 |
Operator FlixBus | Departure Time 05:25AM | Arrival Time 02:40PM | Duration 9h15 | Departure days Thu, Fri | Cheapest price $50 |
Operator regiobus PM | Departure Time 05:37AM | Arrival Time 11:40AM | Duration 6h03 | Departure days Wed | Cheapest price $0 |
Operator regiobus PM | Departure Time 06:33AM | Arrival Time 12:20PM | Duration 5h47 | Departure days Wed | Cheapest price $0 |
Operator regiobus PM | Departure Time 07:33AM | Arrival Time 01:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator Günter Anger Güterverkehrs GmbH & Co. Omnibusvermietung KG | Departure Time 08:00AM | Arrival Time 02:10PM | Duration 6h10 | Departure days Wed | Cheapest price $0 |
Operator regiobus PM | Departure Time 08:33AM | Arrival Time 02:20PM | Duration 5h47 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 09:00AM | Arrival Time 01:30PM | Duration 4h30 | Departure days Thu, Fri | Cheapest price $22 |
Operator RegioJet a.s. | Departure Time 09:15AM | Arrival Time 01:30PM | Duration 4h15 | Departure days Thu, Fri | Cheapest price $22 |
Operator regiobus PM | Departure Time 09:33AM | Arrival Time 03:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator regiobus PM | Departure Time 10:33AM | Arrival Time 04:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 11:00AM | Arrival Time 03:30PM | Duration 4h30 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator RegioJet a.s. | Departure Time 11:15AM | Arrival Time 03:30PM | Duration 4h15 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator regiobus PM | Departure Time 11:33AM | Arrival Time 05:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 05:30PM | Duration 4h30 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator RegioJet a.s. | Departure Time 01:15PM | Arrival Time 05:30PM | Duration 4h15 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator regiobus PM | Departure Time 01:33PM | Arrival Time 07:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator Günter Anger Güterverkehrs GmbH & Co. Omnibusvermietung KG | Departure Time 02:30PM | Arrival Time 08:20PM | Duration 5h50 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 03:00PM | Arrival Time 07:30PM | Duration 4h30 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator RegioJet a.s. | Departure Time 03:15PM | Arrival Time 07:30PM | Duration 4h15 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator regiobus PM | Departure Time 03:33PM | Arrival Time 09:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 05:00PM | Arrival Time 09:30PM | Duration 4h30 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator RegioJet a.s. | Departure Time 05:15PM | Arrival Time 09:30PM | Duration 4h15 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator regiobus PM | Departure Time 05:33PM | Arrival Time 11:30PM | Duration 5h57 | Departure days Wed | Cheapest price $0 |
Operator RegioJet a.s. | Departure Time 07:00PM | Arrival Time 11:30PM | Duration 4h30 | Departure days Thu, Fri, Sat | Cheapest price $18 |
Operator RegioJet a.s. | Departure Time 07:15PM | Arrival Time 11:30PM | Duration 4h15 | Departure days Thu, Fri, Sat | Cheapest price $18 |
Operator regiobus PM | Departure Time 08:51PM | Arrival Time 03:30AM | Duration 6h39 | Departure days Wed | Cheapest price $0 |
Operator Günter Anger Güterverkehrs GmbH & Co. Omnibusvermietung KG | Departure Time 10:07PM | Arrival Time 04:40AM | Duration 6h33 | Departure days Wed | Cheapest price $0 |
Operator FlixBus | Departure Time 10:11PM | Arrival Time 05:00AM | Duration 6h49 | Departure days Fri | Cheapest price $32 |
Buses from Potsdam to Prague with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
Find answers to the most common questions about traveling from Potsdam to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Potsdam to Prague buses use the Potsdam, ZOB am Hauptbahnhof to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Potsdam and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Potsdam, ZOB am Hauptbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several cafes and restaurants nearby.
Wi-Fi is available at Potsdam, ZOB am Hauptbahnhof. ATMs are available at Potsdam, ZOB am Hauptbahnhof.
Ticket office support is available at Potsdam, ZOB am Hauptbahnhof.
Available at Potsdam, ZOB am Hauptbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Potsdam, ZOB am Hauptbahnhof: Handicap accessible with ramps and elevators.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Černý Most is 11 km from Prague city centre. Public transport options include:
Praha, Černý Most has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Černý Most (in the station), Czech Bistro (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located near the entrance and in the main concourse.
Ticket office support is available at Praha, Černý Most.
Available at Praha, Černý Most: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Černý Most: Elevators, ramps.
Check bus stations information for Potsdam and Prague, including where buses depart and arrive on this route.