Why should you book Orlando, FL to Destin, FL buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Orlando, FL to Destin, FL
Take a bus from Orlando, FL to Destin, FL and enjoy the approximately 333 miles (537 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:40, the last at 12:45.
Distance 333 miles (537 km) |
Average bus duration 9h 45m |
Buses per day 2 |
First bus 05:40 |
Last bus 12:45 |
Cheapest month May |
Cheapest day Tue |
High season Oct - Dec |
Low season Apr - Jun |
Bus providers: Greyhound from Orlando, FL to Destin, FLYou can travel by bus between Orlando, FL to Destin, FL with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Orlando, FL to Destin, FL
Find answers to the most common questions about traveling from Orlando, FL to Destin, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Destin, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Orlando, FL to Destin, FL
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Destin, FL
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