- Must visit
Museum of Fine Arts, Boston
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Omio recommends booking the bus as it is the most popular option from Millbrae, CA to Boston, MA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $379 For those with little time, consider booking a bus, which has an average total journey time of 72h 8m. Average ticket prices depend on the travel mode: a bus costs an average of $379, while a bus costs an average of $379.
Distance: 2696 miles (4339 km)
Most popular Bus | Driving |
|---|---|
$379 Average price Cheapest | $638 Average price (fuel + tolls) |
72h 8m Average total duration Fastest 71h 38m Onboard + 30m Additional time* | 45h 31m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Millbrae, CA to Boston, MA:
A bus is $110 less than a flight for this route with tickets for a flight from Millbrae, CA to Boston, MA costing on average $489.
Other travel options to Boston, MA take longer:
Bus takes on average 71h 38m.
Tickets start at around $379 compared to roughly $638 in fuel and tolls — a saving of about $259. The journey takes 71h 38m versus 45h 31m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator SamTrans | Departure Time 11:50AM | Arrival Time 09:50PM | Duration 82h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price $797 |
The table below shows live departures for Millbrae, CA to Boston, MA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:50 AM Millbrae, CA | 82h00 | 9:50 PM Boston, MA | 5 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Millbrae, CA to Boston, MA run on average 2 times per day, taking around 71h 38m. Cheap bus tickets for this journey start at $356 if you book in advance.
The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 2696 miles (4339 km) distance in 71h 20m.
Distance 2696 miles (4339 km) |
Average bus duration 71h 38m |
Cheapest ticket price $356 |
Buses per day 2 |
Fastest bus 71h 20m |
First bus 12:05 AM |
Last bus 11:50 PM |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.
Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.
Historic brick-lined route connecting key revolutionary sites, ideal for first-time visitors seeking Boston's core story on foot.
Elegant public garden famous for swan boats, seasonal flowers, and postcard views in the heart of downtown Boston.
Historic market district and pedestrian-friendly area known for street life, shops, performers, and easy downtown exploring.
Creamy New England chowder with clams, potatoes, and salt pork. It is a defining Boston seafood dish tied to the city's maritime history.
Hot dog bun split on top and filled with chilled lobster meat, usually with butter or mayo. A classic New England summer seafood staple.
Baked cod topped with buttery crumbs, often with lemon. It reflects Boston's long cod fishing tradition and old-school Yankee cooking.
Elegant fine-dining destination by the waterfront known for pristine seafood, tasting menus, and one of Boston's top culinary reputations.
Classic North End Italian restaurant famous for generous portions, old-school service, and beloved Boston dining tradition.
Refined seafood restaurant and oyster bar with polished service, excellent raw bar options, and a Back Bay setting.
Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.
Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.
Find answers to the most common questions about traveling from Millbrae, CA to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

Most Millbrae, CA to Boston, MA buses use the San Francisco, Transit Center Bay 29 to Boston, Bus Terminal South Station station pair. Use this guide to compare Millbrae, CA and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Boston, Bus Terminal South Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food and cafe options available.
Free Wi-Fi available throughout the terminal. ATMs are aTMs located inside the terminal.
Ticket office support is available at Boston, Bus Terminal South Station.
Available at Boston, Bus Terminal South Station: Parking, Taxis, WC.
Accessibility facilities are available at Boston, Bus Terminal South Station: Fully accessible with ramps and elevators.
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