Compare prices and tickets Midland, TX to San Antonio, TX by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Midland, TX to San Antonio, TX buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Midland, TX to San Antonio, TX
Buses from Midland, TX to San Antonio, TX run on average 3 times per day, taking around 16h 19m. Cheap bus tickets for this journey start at $138 (€112) if you book in advance.
The earliest bus runs at 00:20, the last at 20:35. The fastest bus covers the 277 miles (446 km) distance in 12h 55m.
Distance 277 miles (446 km) |
Average bus duration 16h 19m |
Cheapest ticket price $138 (€112) |
Buses per day 3 |
Fastest bus 12h 55m |
First bus 00:20 |
Last bus 20:35 |
Bus providers: Greyhound from Midland, TX to San Antonio, TXYou can travel by bus between Midland, TX to San Antonio, TX with Greyhound for as low as $138 (€112). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Midland, TX to San Antonio, TX
Find answers to the most common questions about traveling from Midland, TX to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Midland, TX to San Antonio, TX
Most popular bus connections from Midland, TX
More options for your journey from Midland, TX to San Antonio, TX
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