Travel Information
Compare bus for Big Pine Key, FL to Key West, FL
Omio recommends booking the bus as it is the most popular option from Big Pine Key, FL to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from $10. For those with little time consider booking a bus which can get you there in 55m. The ticket price range depends on the travel mode: a bus costs an average of $10, and a bus costs an average of $10.
Distance: 27 miles (45 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$12 Average price Cheapest | $7 Average price (fuel + tolls) |
1h 25m Average total duration Fastest 55m Onboard + 30m Additional time* | 49m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
You'll arrive about -1h -6m sooner (55m by bus vs 49m by car) and save roughly $-5.19 (€-4.28) compared to fuel and tolls ($12 (€10) vs $7 (€5)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Big Pine Key, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:45PM | Arrival Time 01:30PM | Duration 0h45 | Departure days Mon | Cheapest price $11 |
Operator Greyhound | Departure Time 01:35PM | Arrival Time 02:30PM | Duration 0h55 | Departure days Mon, Thu | Cheapest price $13 |
Compare prices and tickets Big Pine Key, FL to Key West, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Big Pine Key, FL to Key West, FL buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Big Pine Key, FL to Key West, FL
Buses from Big Pine Key, FL to Key West, FL run on average 2 times per day, taking around 55m. Cheap bus tickets for this journey start at $10 (€8) if you book in advance.
There are 2 buses per day. The earliest bus runs at 08:35, the last at 17:00. The fastest bus covers the 27 miles (45 km) distance in 45m.
Distance 27 miles (45 km) |
Average bus duration 55m |
Cheapest ticket price $10 (€8) |
Buses per day 2 |
Direct buses 2 |
Fastest bus 45m |
First bus 8:35 AM |
Last bus 5:00 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Bus providers: Greyhound from Big Pine Key, FL to Key West, FLYou can travel by bus between Big Pine Key, FL to Key West, FL with Greyhound for as low as $10 (€8). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Big Pine Key, FL to Key West, FL
Find answers to the most common questions about traveling from Big Pine Key, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
Most popular bus connections from Big Pine Key, FL
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