Travel Information
Compare bus for Big Pine Key, FL to Key West, FL
Omio recommends booking the bus as it is the most popular option from Big Pine Key, FL to Key West, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €11 For those with little time, consider booking a bus, which has an average total journey time of 1h 15m. Average ticket prices depend on the travel mode: a bus costs an average of €11, while a bus costs an average of €11.
Distance: 27 miles (45 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
€11 Average price Cheapest | €5 Average price (fuel + tolls) |
1h 15m Average total duration Fastest 45m Onboard + 30m Additional time* | 49m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
You'll arrive about 4m sooner (45m by bus vs 49m by car). Tickets start at around €11 compared to roughly €5 in fuel and tolls — a bit more, but you're getting time back, skipping traffic and parking, and you can work or rest on board.
Driving makes more sense if you're travelling as a group (where fuel splits across several people), want flexibility on timing, or plan to stop en route.
Big Pine Key, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:45PM | Arrival Time 01:30PM | Duration 0h45 | Departure days Mon | Cheapest price €9 |
Operator Greyhound | Departure Time 01:35PM | Arrival Time 02:30PM | Duration 0h55 | Departure days Mon, Thu | Cheapest price €10 |
Compare prices and tickets Big Pine Key, FL to Key West, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Big Pine Key, FL to Key West, FL buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Big Pine Key, FL to Key West, FL
Buses from Big Pine Key, FL to Key West, FL run on average 2 times per day, taking around 45m. Cheap bus tickets for this journey start at €10 if you book in advance.
There are 2 buses per day. The earliest bus runs at 08:35, the last at 17:00. The fastest bus covers the 27 miles (45 km) distance in 45m.
Distance 27 miles (45 km) |
Average bus duration 45m |
Cheapest ticket price €10 |
Buses per day 2 |
Direct buses 2 |
Fastest bus 45m |
First bus 8:35 AM |
Last bus 5:00 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Bus providers: Greyhound from Big Pine Key, FL to Key West, FLYou can travel by bus between Big Pine Key, FL to Key West, FL with Greyhound for as low as €10. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Big Pine Key, FL to Key West, FL
Find answers to the most common questions about traveling from Big Pine Key, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Big Pine Key, FL to Key West, FL
Most Big Pine Key, FL to Key West, FL buses use the Big Pine Key, Overseas Hwy (Greyhound Bus Station) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Big Pine Key, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Big Pine Key, FL station do buses to Key West, FL leave from?
Getting to Big Pine Key, Overseas Hwy (Greyhound Bus Station) from Big Pine Key city centre
Big Pine Key, Overseas Hwy (Greyhound Bus Station) bus station facilities and services
Big Pine Key, Overseas Hwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Big Pine Key, Overseas Hwy (Greyhound Bus Station). ATMs are available at Big Pine Key, Overseas Hwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Big Pine Key, Overseas Hwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Big Pine Key, Overseas Hwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Big Pine Key, Overseas Hwy (Greyhound Bus Station): Limited accessibility for disabled passengers.
Which Key West, FL station do buses from Big Pine Key, FL arrive at?
Getting to Key West, South Roosevelt Boulevard (Key West International Airport) from Key West city centre
Key West, South Roosevelt Boulevard (Key West International Airport) is 2 km from Key West city centre. Public transport options include:
Key West, South Roosevelt Boulevard (Key West International Airport) bus station facilities and services
Key West, South Roosevelt Boulevard (Key West International Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Key West, South Roosevelt Boulevard (Key West International Airport). ATMs are available at Key West, South Roosevelt Boulevard (Key West International Airport).
Tickets and information
Ticket office support is available at Key West, South Roosevelt Boulevard (Key West International Airport).
Parking, taxis and toilets
Available at Key West, South Roosevelt Boulevard (Key West International Airport): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Key West, South Roosevelt Boulevard (Key West International Airport): The station is wheelchair accessible.
Most popular bus connections from Big Pine Key, FL
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