Anderson, SC to Jacksonville, FL bus with FlixBus

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2,000+ travel companies
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Travel Information

Compare bus for Anderson, SC to Jacksonville, FL

Omio recommends booking the flight as it is the most popular option from Anderson, SC to Jacksonville, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $173 For those with little time, consider booking a flight, which has an average total journey time of 4h 54m. Average ticket prices depend on the travel mode: a bus costs an average of $173, while a flight costs an average of $858.

Distance: 293 miles (473 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$173

Average price

Cheapest

$858

Average price

$343

Average price

$70

Average price

(fuel + tolls)

9h 25m

Average total duration

8h 55m

Onboard

+

30m

Additional time*

4h 54m

Average total duration

Fastest

2h 54m

Onboard

+

2h 0m

Additional time*

23h 12m

Average total duration

22h 42m

Onboard

+

30m

Additional time*

5h 55m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

American Airlines

Most popular airline

Amtrak

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Anderson, SC to Jacksonville, FL is a bus with an average price of $173.

This is compared to other travel options from Anderson, SC to Jacksonville, FL:

A bus is $171 less than a train for this route with tickets for a train from Anderson, SC to Jacksonville, FL costing on average $343.

A bus is $685 less than a flight for this route with tickets for a flight from Anderson, SC to Jacksonville, FL costing on average $858.

The fastest way to travel from Anderson, SC to Jacksonville, FL is by flight with an average journey time of 2h 54m.

Other travel options to Jacksonville, FL take longer:

Bus takes on average 8h 55m.

Train takes on average 22h 42m.

Yes, you can take a between Anderson, SC and Jacksonville, FL.
We recommend using the bus as it is the most popular way to get from Anderson, SC to Jacksonville, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $173 compared to roughly $70 in fuel and tolls — a saving of about $-103.28. The journey takes 8h 55m versus 5h 55m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Anderson, SC to Jacksonville, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:55AM
Arrival Time
06:35PM
Duration
12h40
Departure days
Thu
Cheapest price
$166
Operator
FlixBus
Departure Time
03:50PM
Arrival Time
03:05AM
Duration
11h15
Departure days
Thu
Cheapest price
$181

Compare prices and tickets Anderson, SC to Jacksonville, FL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Sep 20
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Sep 21
Tue
Sep 22
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Sep 23
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Sep 24
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Sep 25
Sat
Sep 26

Why should you book Anderson, SC to Jacksonville, FL buses with Omio?

FlixBus operates all buses services from Anderson, SC to Jacksonville, FL.
Omio is an official ticket reseller for all your travel options from Anderson, SC to Jacksonville, FL.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Anderson, SC to Jacksonville, FL

USAUSA
USAUSA
Icon of bus

Buses from Anderson, SC to Jacksonville, FL run on average 3 times per day, taking around 8h 55m. Cheap bus tickets for this journey start at $159 if you book in advance.

The earliest bus runs at 09:05, the last at 18:30. The fastest bus covers the 293 miles (473 km) distance in 8h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
293 miles (473 km)
Average bus duration
8h 55m
Cheapest ticket price
$159
Buses per day
3
Fastest bus
8h 35m
First bus
9:05 AM
Last bus
6:30 PM
Cheapest Month
Oct
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Anderson, SC to Jacksonville, FLYou can travel by bus between Anderson, SC to Jacksonville, FL with FlixBus for as low as $159. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
8h 35m
Cheapest FlixBus Price
$159
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Jacksonville, FL

Things to do in Jacksonville, FL

Discover the best of Jacksonville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville, FL trip today.

  • Must visit

Cummer Museum of Art & Gardens

Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.

  • Recommended

Museum of Science & History

Regional history museum covering Northeast Florida through engaging exhibits on city growth, culture, and key local events.

  • Recommended

Museum of Contemporary Art Jacksonville

Contemporary art museum in the university district, presenting rotating exhibitions and thoughtful programs by living artists.

US dollar ($)

Moderate for US beach cities. Hotels vary by season; meals and coffee are typical US prices, and most visitors need a car as transit is limited.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$20-40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$3-6 for drip coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, more for great service. Taxis usually get 10-15%. Cafes often use tip jars or screens; $1-2 is common.

FAQs: Bus from Anderson, SC to Jacksonville, FL

Find answers to the most common questions about traveling from Anderson, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Anderson, SC to Jacksonville, FL can start from as little as $159 when you book in advance. The average bus ticket price for Anderson, SC to Jacksonville, FL is $173 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Anderson, SC to Jacksonville, FL is 8h 35m to travel the 293 miles (473 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Anderson, SC to Jacksonville, FL leaves at 9:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Anderson, SC to Jacksonville, FL leaves at 6:30 PM.
There are 3 buses a day from Anderson, SC to Jacksonville, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Anderson, SC to Jacksonville, FL, you can count on FlixBus for the best way to get you to Jacksonville, FL. You can also check all possible bus companies who offer a service between Anderson, SC and Jacksonville, FL and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Anderson, Highway 81 S (Greyhound Bus Station), SC, which is located around 8 miles (14 km) away from the city centre, and they get off the bus at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St, located 1 away from the city centre.
A trip to Jacksonville, FL from Anderson, SC is worth doing but not as a day trip with a journey time of 8h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Anderson, SC to Jacksonville, FL is October.
Yes, you can take a between Anderson, SC and Jacksonville, FL.
Yes, the following accessibility options are available when taking the bus from Anderson, SC to Jacksonville, FL:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Anderson, SC to Jacksonville, FL for bus company FlixBus.
Whether you can cancel your bus ticket from Anderson, SC to Jacksonville, FL depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Anderson, SC to Jacksonville, FL.
Yes, the following luggage options are included when booking a bus ticket from Anderson, SC to Jacksonville, FL:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Anderson, SC to Jacksonville, FL:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Anderson, SC to Jacksonville, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Anderson, SC to Jacksonville, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Anderson, SC to Jacksonville, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Anderson, SC to Jacksonville, FL with the following bus company: FlixBus.
Since neither Anderson, SC nor Jacksonville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Anderson, SC to Jacksonville, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Anderson, SC to Jacksonville, FL

Most Anderson, SC to Jacksonville, FL buses use the Anderson, Highway 81 S (Greyhound Bus Station) to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St station pair. Use this guide to compare Anderson, SC and Jacksonville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Anderson
Arrival bus stations in Jacksonville

Which Anderson, SC station do buses to Jacksonville, FL leave from?

Buses from Anderson, SC to Jacksonville, FL leave from Anderson, Highway 81 S (Greyhound Bus Station). The station is 9 miles (15 km) from Anderson, SC city centre at Anderson, SC, USA.
Anderson, Highway 81 S (Greyhound Bus Station)Anderson, SC, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Anderson, Highway 81 S (Greyhound Bus Station) from Anderson city centre

Anderson, Highway 81 S (Greyhound Bus Station) is 14 km from Anderson city centre. Public transport options include:

TrainPalmetto · 13h 34m · $273
BusGreyhound US0643S · 12h 27m · $142
Greyhound US0660s · 13h 6m · $164

Anderson, Highway 81 S (Greyhound Bus Station) bus station facilities and services

Anderson, Highway 81 S (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Free WiFi in waiting area. ATMs are available at Anderson, Highway 81 S (Greyhound Bus Station).

Tickets and information

Ticket office support is available at Anderson, Highway 81 S (Greyhound Bus Station).

Parking, taxis and toilets

Available at Anderson, Highway 81 S (Greyhound Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Anderson, Highway 81 S (Greyhound Bus Station): Wheelchair accessible entrance and seating.

Most popular bus connections from Anderson, SC

More options for your journey from Anderson, SC to Jacksonville, FL

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Jacksonville, FLAnderson, SC to Jacksonville, FL bus

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