- Must visit
Cummer Museum of Art & Gardens
Major art museum on the St. Johns River with a strong permanent collection and historic formal gardens. One of Jacksonville’s best-known cultural attractions.
Omio recommends booking the bus as it is the most popular option from Anderson, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $168. For those with little time consider booking a flight which can get you there in 4h 8m. The ticket price range depends on the travel mode: a bus costs an average of $168, and a flight costs an average of $296.
Distance: 293 miles (473 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$176 Average price Cheapest | $268 Average price | $336 Average price | $69 Average price (fuel + tolls) |
12h 28m Average total duration 11h 58m Onboard + 30m Additional time* | 29h 21m Average total duration 28h 51m Onboard + 30m Additional time* | 7h 8m Average total duration Fastest 4h 8m Onboard + 3h 0m Additional time* | 5h 55m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Anderson, SC to Jacksonville, FL:
A bus is $92 (€74) less than a train for this route with tickets for a train from Anderson, SC to Jacksonville, FL costing on average $268 (€216).
A bus is $160 (€129) less than a flight for this route with tickets for a flight from Anderson, SC to Jacksonville, FL costing on average $336 (€271).
Other travel options to Jacksonville, FL take longer:
Bus takes on average 11h 58m.
Train takes on average 28h 51m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:55AM | Arrival Time 06:35PM | Duration 12h40 | Departure days Thu | Cheapest price $168 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 03:05AM | Duration 11h15 | Departure days Thu | Cheapest price $184 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Anderson, SC to Jacksonville, FL run on average 3 times per day, taking around 11h 58m. Cheap bus tickets for this journey start at $168 (€135) if you book in advance.
The earliest bus runs at 09:05, the last at 18:30. The fastest bus covers the 293 miles (473 km) distance in 11h 15m.
Distance 293 miles (473 km) |
Average bus duration 11h 58m |
Cheapest ticket price $168 (€135) |
Buses per day 3 |
Fastest bus 11h 15m |
First bus 9:05 AM |
Last bus 6:30 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Discover the best of Jacksonville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville trip today.
Major art museum on the St. Johns River with a strong permanent collection and historic formal gardens. One of Jacksonville’s best-known cultural attractions.
The Museum of Science & History features science, regional history, and family-friendly exhibits on the Southbank. It is one of Jacksonville’s most popular museums.
Downtown contemporary art museum presenting rotating exhibitions, modern works, and public programs. A top stop for current visual culture in the city.
Scenic pedestrian route along both sides of the St. Johns River with skyline views, bridges, and easy access to downtown sights. One of the city’s best walks.
Historic neighborhood district known for walkable streets, boutiques, parks, and preserved architecture. Very popular with locals for casual exploring and photos.
The city’s best-known beach area with a broad sandy shoreline, fishing pier area, and active promenade atmosphere. Strong social media appeal, especially at sunrise.
Wild-caught shrimp from nearby Mayport, commonly served fried, grilled, blackened, or in baskets and tacos. It is one of the area’s best-known local seafood specialties.
A classic Jacksonville beach-area meal featuring local shrimp, fries, and slaw. It is especially associated with casual seafood spots near the coast.
A regional coastal feast of shrimp, sausage, corn, and potatoes boiled with seasoning. Popular in Northeast Florida and commonly shared at casual gatherings.
A well-known local-born breakfast and brunch spot famous for Southern biscuit sandwiches, gravy, and a relaxed neighborhood feel.
A popular Jacksonville barbecue restaurant serving smoked meats, hearty sides, and craft beer in a lively, casual setting.
An upscale downtown steakhouse in a historic building, known for steaks, seafood, rooftop dining, and polished service.
Generally moderate for U.S. city travel. Meals and transport are reasonable, while beachfront stays cost more.
Tip 15-20% at restaurants. Bartenders: USD 1-2 per drink. Taxis and rideshares: 10-15% or round up. Hotel staff: USD 2-5 for bags; USD 2-5 nightly for housekeeping.
Find answers to the most common questions about traveling from Anderson, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need