Anderson, SC to Jacksonville, FL bus

Wed, May 27
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for Anderson, SC to Jacksonville, FL

Omio recommends booking the bus as it is the most popular option from Anderson, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $168. For those with little time consider booking a flight which can get you there in 4h 8m. The ticket price range depends on the travel mode: a bus costs an average of $168, and a flight costs an average of $296.

Distance: 293 miles (473 km)

Compare bus with

Most popular
Bus
Train
Flight
Driving

$176

Average price

Cheapest

$268

Average price

$336

Average price

$69

Average price

(fuel + tolls)

12h 28m

Average total duration

11h 58m

Onboard

+

30m

Additional time*

29h 21m

Average total duration

28h 51m

Onboard

+

30m

Additional time*

7h 8m

Average total duration

Fastest

4h 8m

Onboard

+

3h 0m

Additional time*

5h 55m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Anderson, SC to Jacksonville, FL is a bus with an average price of $176 (€142).

This is compared to other travel options from Anderson, SC to Jacksonville, FL:

A bus is $92 (€74) less than a train for this route with tickets for a train from Anderson, SC to Jacksonville, FL costing on average $268 (€216).

A bus is $160 (€129) less than a flight for this route with tickets for a flight from Anderson, SC to Jacksonville, FL costing on average $336 (€271).

The fastest way to travel from Anderson, SC to Jacksonville, FL is by flight with an average journey time of 4h 8m.

Other travel options to Jacksonville, FL take longer:

Bus takes on average 11h 58m.

Train takes on average 28h 51m.

It's helpful to compare your options as there are 3 ways to travel between Anderson, SC and Jacksonville, FL including taking a bus, train, and flight.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Anderson, SC to Jacksonville, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:55AM
Arrival Time
06:35PM
Duration
12h40
Departure days
Thu
Cheapest price
$168
Operator
FlixBus
Departure Time
03:50PM
Arrival Time
03:05AM
Duration
11h15
Departure days
Thu
Cheapest price
$184

Compare prices and tickets Anderson, SC to Jacksonville, FL by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
May 27
Thu
May 28
Fri
May 29
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May 30
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May 31
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Jun 01
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Jun 02

Journey information

Overview: Bus from Anderson, SC to Jacksonville, FL

USAUSA
USAUSA
Icon of bus

Buses from Anderson, SC to Jacksonville, FL run on average 3 times per day, taking around 11h 58m. Cheap bus tickets for this journey start at $168 (€135) if you book in advance.

The earliest bus runs at 09:05, the last at 18:30. The fastest bus covers the 293 miles (473 km) distance in 11h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
293 miles (473 km)
Average bus duration
11h 58m
Cheapest ticket price
$168 (€135)
Buses per day
3
Fastest bus
11h 15m
First bus
9:05 AM
Last bus
6:30 PM
Cheapest Month
Oct
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Complete guide to Jacksonville

Things to do in Jacksonville

Discover the best of Jacksonville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville trip today.

  • Must visit

Cummer Museum of Art & Gardens

Major art museum on the St. Johns River with a strong permanent collection and historic formal gardens. One of Jacksonville’s best-known cultural attractions.

  • Must visit

MOSH

The Museum of Science & History features science, regional history, and family-friendly exhibits on the Southbank. It is one of Jacksonville’s most popular museums.

  • Recommended

Museum of Contemporary Art Jacksonville

Downtown contemporary art museum presenting rotating exhibitions, modern works, and public programs. A top stop for current visual culture in the city.

United States Dollar

Generally moderate for U.S. city travel. Meals and transport are reasonable, while beachfront stays cost more.

Average meal costs

Budget
USD 10-15 for fast food or a casual lunch.
Mid-range
USD 20-40 per person at a standard restaurant.
Fine dining
USD 60+ per person at upscale restaurants.
Coffee
USD 3-6 for drip coffee or a latte.

Tipping culture

Tip 15-20% at restaurants. Bartenders: USD 1-2 per drink. Taxis and rideshares: 10-15% or round up. Hotel staff: USD 2-5 for bags; USD 2-5 nightly for housekeeping.

FAQs: Bus from Anderson, SC to Jacksonville, FL

Find answers to the most common questions about traveling from Anderson, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Anderson, SC to Jacksonville, FL can start from as little as $168 (€135) when you book in advance. The average bus ticket price for Anderson, SC to Jacksonville, FL is $176 (€142) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Anderson, SC to Jacksonville, FL is 11h 15m to travel the 293 miles (473 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Anderson, SC to Jacksonville, FL leaves at 9:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Anderson, SC to Jacksonville, FL leaves at 6:30 PM.
A trip to Jacksonville, FL from Anderson, SC is worth doing but not as a day trip with a journey time of 11h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Anderson, SC to Jacksonville, FL is October.
It's helpful to compare your options as there are 3 ways to travel between Anderson, SC and Jacksonville, FL including taking a bus, train, and flight.
No, the bus from Anderson, SC to Jacksonville, FL has no accessibility options.
No, there are no bathrooms on board the bus from Anderson, SC to Jacksonville, FL.
No, bikes are not allowed on board the bus from Anderson, SC to Jacksonville, FL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Anderson, SC to Jacksonville, FL.
No, luggage for the bus from Anderson, SC to Jacksonville, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from Anderson, SC to Jacksonville, FL.
Unfortunately, pets are not allowed on the bus from Anderson, SC to Jacksonville, FL.
No, there are no USB plugs on board the bus from Anderson, SC to Jacksonville, FL.
No, there is no WiFi on board the bus from Anderson, SC to Jacksonville, FL.
Since neither Anderson, SC nor Jacksonville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Anderson, SC to Jacksonville, FL

Anderson
Jacksonville
The major bus station for departures in Anderson is Anderson, Highway 81 S (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Anderson, Highway 81 S (Greyhound Bus Station) for your trip from Anderson to Jacksonville.
Anderson, Highway 81 S (Greyhound Bus Station)
information

Most popular bus connections from Anderson, SC

More options for your journey from Anderson, SC to Jacksonville, FL

Here are some other resources that might have the information you need

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